- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Tracheal and airway disorders
- SARS-CoV-2 and COVID-19 Research
- Airway Management and Intubation Techniques
- COVID-19 and Mental Health
- Palliative Care and End-of-Life Issues
- Intraperitoneal and Appendiceal Malignancies
- Appendicitis Diagnosis and Management
- Antifungal resistance and susceptibility
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Sepsis Diagnosis and Treatment
- Parasitic Diseases Research and Treatment
- Pain Management and Opioid Use
- Hemodynamic Monitoring and Therapy
- Pancreatitis Pathology and Treatment
- Thermal Regulation in Medicine
- Antibiotic Use and Resistance
- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Parasites and Host Interactions
- Neurogenetic and Muscular Disorders Research
All India Institute of Medical Sciences
2016-2024
Cancer Institute (WIA)
2020-2023
DR. B.R.A. Institute Rotary Cancer Hospital
2019-2022
All India Institute of Medical Sciences Raipur
2019-2022
All India Institute of Medical Sciences Bhopal
2019-2022
Voluntary Health Association Of India
2022
Wythenshawe Hospital
1992
In December 2019, a novel coronavirus (SARS-CoV-2) emerged in China and rapidly spread globally including India. The characteristic clinical observations outcomes of this disease (COVID-19) have been reported from different countries. present study was aimed to describe the clinico-demographic characteristics in-hospital group COVID-19 patients north India.This prospective, single-centre collection data regarding epidemiological, demographic, laboratory parameters, management outcome...
To evaluate the efficacy and safety of pegylated interferon alfa-2b (PEG IFN-α2b) along with standard care (SOC) in subjects moderate COVID-19.In this phase 2, randomized, open-label study, adult aged ≥18 years RT-PCR confirmed COVID-19 symptoms were randomized a 1:1 to receive PEG IFN-α2b plus SOC, or SOC alone. The primary endpoint was improvement clinical status on day 15, measured by WHO 7-point ordinal scale.Forty (n = 20) 20). Overall, 19 (95.00%) had achieved 15 compared 13 (68.42%)...
To determine the efficacy of probiotic Bifidobacterium longum CECT 7347 (ES1) and postbiotic heat-treated (HT-ES1) in improving symptom severity adults with diarrhea-predominant irritable bowel syndrome (IBS-D), a randomised, double-blind, placebo-controlled trial 200 participants split into three groups was carried out. Two capsules either ES1, HT-ES1 or placebo were administered orally, once daily, for 84 days (12 weeks). The primary outcome change total IBS-Symptom Severity Scale...
Abstract Introduction: Till date, no drug has shown definite benefit in non-severe COVID-19. Ivermectin is an antiparasitic which in-vitro efficacy reducing coronavirus-2 (SARS-CoV-2) load severe disease. Objectives: To determine if a single oral administration of to patients with mild and moderate COVID-19 effective converting SARS-CoV-2 RT-PCR negative result viral load. Methods: In this double-blind trial, were randomized elixir formulation 24 mg, 12 mg or placebo 1:1:1 ratio. The...
Hypoxia in patients with COVID-19 is one of the strongest predictors mortality. Silent hypoxia characterised by presence without dyspnoea. has been shown to affect outcome previous studies.
The corona virus disease-19 (COVID-19) pandemic has affected every domain of human health be it physical or mental. uncertainty disease progression in patients with SARS-CoV-2 infection can lead to major psychological and psychiatric concerns that should not overlooked. interventions directed the vulnerable population help them mitigate stress anxiety caused by isolation. We evaluated effect meditation breathing exercises on well-being under institutional isolation.We conducted a randomized...
Background: While long-term studies on the correlates of protection, vaccine effectiveness, and enhanced surveillance are awaited for SARS-CoV-2 vaccine, breakthrough infections help understand nature course this illness among vaccinated individuals guide in public health preparedness. This study aims to compare differences hospitalization outcomes infection fully with those unvaccinated partially individuals. Materials Methods: Single institution observational cohort study. compared...
Abstract Background- The sharp uptick in the cases of mucormycosis background COVID19 pandemic is a cause concern and reasons it’s impact remains to be seen. We studied clinical characteristics patients with co-infection performed literature review. Methods- This retrospective study was conducted at tertiary centre India. All admitted were included, details obtained from hospital records. did review literatures using terms “SARS-CoV2” OR “COVID19” AND “Mucormycosis” “co-infection” on Pubmed...
Health-care professionals (HCPs) are the frontline warriors in time of this uncertain and unpredictable crisis COVID. They face many challenges while caring for these patients, yet they expected to cope with it deliver their duties betterment humankind. Our primary aim was identify assess concerns HCPs working COVID area a tertiary institutional isolation center.An online Google-based questionnaire survey distributed through various social media platforms after approval review board total...
Background and objective It has been observed that peripheral oxygen saturation (SpO2) measured by pulse oximeter is consistently lower than arterial (SaO2) directly blood gas analysis. In this study, we aimed to evaluate the correlation between SpO2 SaO2, partial pressure of (PaO2), compare SpO2/FiO2 (SF) PaO2/FiO2 (PF) ratios in patients with coronavirus disease 2019 (COVID-19). Methods observational was recorded analysis performed among 70 COVID-19 presenting on room air (FiO2 = 0.21)....
Background: Year 2020 started with global health crisis known as COVID-19. In lack of established tools and management protocols, COVID-19 had become breeding ground for fear confusion, leading to stigma toward affected individuals. Method: A cross-sectional study was conducted estimate prevalence in discharged patients from a COVID hospital India. Participants were approached telephonically using semistructured questionnaire record their experiences. Questions asked regarding at six major...
The "second wave" of the COVID-19 pandemic hit India from early April 2021 to June 2021. We describe clinical features, treatment trends, and baseline laboratory parameters a cohort patients with SARS-CoV-2 infection their association outcome.
Acute loss of smell or anosmia is a common and sometimes the only symptom observed in patients with coronavirus disease-2019 (COVID-19). The objective study was to determine prevalence, time onset, duration COVID-19 infection association other symptoms eosinophil count.Two hundred laboratory-confirmed infection, who were asymptomatic mildly symptomatic assessed for olfaction nonirritant odor. presence recorded, questionnaire integrating reporting tool filled. Patients anosmia/hyposmia...
In a patient who had sudden onset of bilateral diaphragmatic paralysis after forceful neck manipulation complete, though gradual, recovery in lung function and transdiaphragmatic pressures was seen over three years. This is previously unrecognised risk osteopathy.
Abstract Background Due to the unprecedented speed of SARS-CoV-2 vaccine development, their efficacy trials and issuance emergency use approvals marketing authorizations, additional scientific questions remain that need be answered regarding effectiveness, vaccination regimens for booster doses. While long-term studies on correlates protection, enhanced surveillance are awaited, breakthrough infections help us understand nature course this illness among vaccinated individuals guide in public...
Pulmonary alveolar proteinosis (PAP) is an uncommon lung disease characterized by excessive accumulation of pulmonary surfactant that usually requires treatment with whole-lung lavage. A 47-year-old female presented history dry cough and breathlessness for past 6months. Chest radiograph demonstrated bilateral shadows highresolution computerized tomography thorax showed crazy paving pattern. Broncho-alveolar lavage (BAL) transbronchial biopsy confirmed a diagnosis PAP. Due to worsening...
Background COVID-19 has spread as two distinct surges of cases in many countries. Several countries have reported differences disease severity and mortality the waves. Objective Compare in-hospital waves at a tertiary care hospital India. Methods We conducted retrospective data collection. Distinct periods admissions were defined first wave spanning from March 2020 to December second April 2021 June 21, 2021. The primary outcome this study was compare rates terms total rate (TMR) case...
Abstract Background The second wave of the COVID-19 pandemic hit India from early April 2021 to June and more than 400,000 cases per day were reported in country. We describe clinical features, demography, treatment trends, baseline laboratory parameters a cohort patients admitted at All Institute Medical Sciences, New Delhi with SARS-CoV-2 infection their association outcome. Methods This was retrospective study describing clinical, patterns consecutive infection. Multivariate logistic...
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is associated increased morbidity and mortality. We retrospectively analysed the perioperative anesthetic management in patients undergoing HIPEC surgery.After ethics approval, we reviewed records of who underwent CRS/HIPEC from 2015 until 2020. noted peritoneal carcinomatosis index (PCI), blood loss, anastomoses done, total amount fluid given, delta temperature duration surgery. These were correlated need for...
Background Cancer-associated depression is a multifaceted condition that arises from the interplay of biological, psychological, and social factors in individuals diagnosed with cancer. Understanding background this involves exploring how cancer its treatments can precipitate depressive symptoms mechanisms behind association. Objective To describe synthesize information on complicated interactions between chronic stress, inflammation, immunological responses, development. review existing...