A5027912960- Pregnancy and Medication Impact
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- COVID-19 Clinical Research Studies
- Eosinophilic Esophagitis
- Long-Term Effects of COVID-19
- Hematological disorders and diagnostics
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Drug-Induced Hepatotoxicity and Protection
- Vitamin C and Antioxidants Research
- Inflammasome and immune disorders
- Pregnancy and preeclampsia studies
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Pharmacological Receptor Mechanisms and Effects
- Neonatal Respiratory Health Research
- Contact Dermatitis and Allergies
Hvidovre Hospital
2020-2023
Copenhagen University Hospital
2021-2023
University of Copenhagen
2020-2021
Combining the antibiotic azithromycin and hydroxychloroquine induces airway immunomodulatory effects, with latter also having
Asthma has been linked with prolonged time to pregnancy compared healthy controls, also asthma a higher need for fertility treatment. However, knowledge of the possible association between allergy and treatment is limited. Our aim was explore difference in having had women live births those perennial (animals, fungi dust mites) no allergy/seasonal allergy. The primary outcome interest treatment.Women enrolled Management during Pregnancy (MAP) program at Hvidovre Hospital, DK, were included...
Asthma is associated with prolonged time to pregnancy and a higher need for fertility treatment. However, the mechanism underlying this association remains incompletely understood. Previous research points asthma-driven systemic inflammation also affecting reproductive organs thereby fertility. The aim of study was determine if treatment omalizumab prior will increase rate among women asthma by decreasing asthma-related and, that, provide insight into mechanisms.This an ongoing prospective...
<b>Background:</b> Women with asthma have an increased risk of spontaneous abortion compared to non-asthmatic women, but, a possible association between and recurrent pregnancy loss (RPL), defined as ≥3 abortions, has, so far, not been investigated. Since inflammation is involved in both RPL, we hypothesized that the would be stronger women RPL. <b>Objective:</b> To investigate if associated loss. <b>Methods:</b> Using Danish national registers, identified all born from 1957 1997 diagnosis...
Objective We investigate symptoms of anxiety and depression among women with asthma prior to fertility treatment.Methods This is a cross-sectional study screened for eligibility the PRO-ART (RCT omalizumab versus placebo in asthmatic undergoing treatment (NCT03727971)). All participants were scheduled vitro fertilization (IVF) at four public clinics Denmark. Data on demographics control (ACQ-5) obtained. Symptoms assessed using Hospital Anxiety Depression Scale (HADS-A D, respectively)...
<b>Background:</b> Women with asthma require fertility treatment more frequently and have longer time to pregnancy, together a higher risk of pregnancy loss. Type 2 inflammatory cells (eosinophils, mast cells) undergo cyclic changes in the uterus. It is, however, unknown whether this contributes impaired among women asthma. <b>Aim:</b> To explore if endometrium compared non-asthmatic women. <b>Method:</b> Thirty without (1:1) receiving were studied. Asthma was defined as respiratory symptoms...
<b>Background:</b> A combination of azithromycin and hydroxychloroquine (HCQ) with airway immunomodulatory effects the latter also <i>in vitro</i> antiviral properties may improve outcomes in patients hospitalized for COVID-19. <b>Methods:</b> Placebo-controlled randomized multicenter trial. Patients ≥18 years old, admitted to hospital ≤ 48 hours, not an ICU, having a positive SARS-CoV-2 PCR-test, fulfilling no exclusion criteria, were recruited. The intervention was 500 mg daily three days...
<b>Background:</b> Hydroxychloroquine has been proposed as a primary prophylactic agent against COVID-19. We aimed to investigate if patients treated with hydroxychloroquine for non-COVID-19 indication had lower risk of PCR-verified infection SARS-CoV-2, compared matched controls. <b>Methods:</b> A cohort comprising all persons in Denmark before Jan 1st 2020 (i.e. SARS-CoV-2 was confirmed Denmark) by age and sex Data were collected using the Danish national registries containing complete...