Wen Yao

ORCID: 0000-0002-3726-7716
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About
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Research Areas
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Animal Nutrition and Physiology
  • Phytoestrogen effects and research
  • Systemic Lupus Erythematosus Research
  • Ruminant Nutrition and Digestive Physiology
  • Effects and risks of endocrine disrupting chemicals
  • Adipose Tissue and Metabolism
  • Meat and Animal Product Quality
  • Hydrogen's biological and therapeutic effects
  • Reproductive System and Pregnancy
  • Effects of Environmental Stressors on Livestock
  • Biochemical effects in animals
  • Complement system in diseases
  • Protein Hydrolysis and Bioactive Peptides
  • Animal Behavior and Welfare Studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Antibiotic Resistance in Bacteria
  • Reproductive Health and Technologies
  • Clostridium difficile and Clostridium perfringens research
  • Ovarian function and disorders
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Birth, Development, and Health
  • Biopolymer Synthesis and Applications
  • Food composition and properties

Nanjing Agricultural University
2016-2025

Henan Agricultural University
2025

First People's Hospital of Chongqing
2025

Chinese People's Liberation Army
2023-2024

Chongqing Medical and Pharmaceutical College
2024

Ministry of Agriculture and Rural Affairs
2019-2024

Shanghai Institute of Technology
2024

Tongji Hospital
2019-2024

Huazhong University of Science and Technology
2019-2024

Central Hospital of Wuhan
2024

Abstract Objectives To develop and validate the performance of CT-based radiomics models for predicting prognosis acute pancreatitis. Methods All 344 patients (51 ± 15 years, 171 men) in a first episode pancreatitis (AP) were retrospectively enrolled randomly divided into training ( n = 206), validation 69), test 69) sets with ratio 6:2:2. The dichotomized good poor subgroups based on follow-up CT clinical data. features extracted from contrast-enhanced CT. Logistic regression analysis was...

10.1186/s13244-024-01887-2 article EN cc-by Insights into Imaging 2025-01-09

Heat stress (HS) jeopardizes intestinal barrier functions and augments permeability in pigs. However, whether HS-induced maternal microbial metabolic changes primiparous sows during late gestation remains elusive. We present here, a study investigating the fecal responses gestational when exposed to HS.Twelve first-parity Landrace × Large White F1 were randomly assigned into two environmental treatments including thermoneutral (TN) (18-22 °C; n = 6) HS (28-32 conditions. Both applied from 85...

10.1186/s40104-019-0391-0 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2019-11-04

This present study investigated the changes in bacterial community composition, with an emphasis on Lactobacillus spp. and Streptococcus suis populations as potentially beneficial harmful groups, stomach, jejunum ileum of piglets after weaning (21 days postpartum) by 16S rRNA gene-based methods. Denaturing gradient gel electrophoresis analysis showed that, weaning, predominant bands related to disappeared were replaced potential pathogenic species, such Peptostreptococcus anaerobius,...

10.1111/j.1574-6941.2008.00529.x article EN FEMS Microbiology Ecology 2008-06-12

Short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate, are the main products of microbial fermentation in gut might mediate some effects microbiota nutrition on development, metabolism, pathogenesis obesity other diseases.The objective this study was to determine SCFAs adipocyte differentiation underlying mechanism.The stromal vascular fraction (SVF) porcine subcutaneous fat used as preadipocyte model. Adipocyte assessed by Oil Red O staining gene expression analysis...

10.3945/jn.114.198531 article EN publisher-specific-oa Journal of Nutrition 2014-10-16

Unabsorbed copper accumulates in the hindgut of pigs that consume high levels dietary copper, which enhances coselection antibiotic-resistant bacteria and is considered detrimental to environment porcine health. In our study, a combination 16S rRNA pyrosequencing nontargeted metabolomics was used investigate microbiome-metabolome responses suckling piglets. The results showed level affected abundance several Clostridia genera relative butyrate-producing bacteria, such as Coprococcus,...

10.1007/s00253-018-9533-0 article EN cc-by Applied Microbiology and Biotechnology 2018-12-07

Di(2-ethylhexyl) phthalate (DEHP) is a widely recognized environmental endocrine disruptor that potentially impacts female reproductive function, although the specific mechanisms leading to such impairment remain unclear. A growing body of research has revealed endoplasmic reticulum and mitochondrial function significantly influence oocyte quality. The structure mitochondria-associated membranes (MAMs) crucial for facilitating exchange Ca

10.1016/j.ecoenv.2024.116679 article EN cc-by Ecotoxicology and Environmental Safety 2024-07-08

The resting postures of piglets are crucial indicators for assessing their health status and environmental comfort. This study proposes a posture recognition method during lactation based on the PPR-YOLO model, aiming to enhance detection accuracy classification capability different piglet postures. Firstly, address issue numerous sows in farrowing house that easily occlude each other, an image edge algorithm is employed precisely locate sow’s bed area. By cropping images, irrelevant...

10.3390/agriculture15030230 article EN cc-by Agriculture 2025-01-21

Abstract Cold damage poses a significant challenge to the cultivation of soft-seeded pomegranate varieties, hindering growth industry. The genetic basis cold tolerance in pomegranates has remained elusive, largely due lack high-quality genome assemblies for cold-tolerant varieties and comprehensive population-scale genomic studies. In this study, we addressed these challenges by assembling chromosome-level reference 'Sanbai', variety renowned its freezing resistance, achieving an impressive...

10.1093/hr/uhaf022 article EN cc-by Horticulture Research 2025-01-21

Background Several studies have suggested that a healthy diet is associated with improved male fertility outcomes. However, the joint and individual associations between status of multiple vitamins sperm quality remain unclear. Objectives This study aimed to investigate serum vitamin levels parameters in adult men. Methods A cross-sectional was conducted among 156 men seeking care at reproductive center from December 2023 June 2024. Blood semen were collected on same day determine...

10.3389/fnut.2025.1534309 article EN cc-by Frontiers in Nutrition 2025-03-28

Transformation of daidzein to equol was compared during fermentation three growth media inoculated with faeces from Erhualian piglets, but produced only one medium, M1. Two equol-producing strains (D1 and D2) were subsequently isolated using medium Both identified as Eubacterium sp., on the basis morphological physiological characteristics, 16S rRNA gene sequence analysis showed that D1 D2 most closely related previously characterized daidzein-metabolizing bacteria human faecal rumen...

10.1111/j.1574-6968.2008.01108.x article EN FEMS Microbiology Letters 2008-03-05

Short-chain fatty acids (SCFAs) are not only an important energy source, but they also play a regulatory role in various physiological processes humans and rodents. Current studies, mostly rodents, have revealed that SCFAs acted as endogenous ligands for G protein-coupled receptor GPR41 GPR43. Whether proteins similar to human GPR43 mediate the effects of swine remains unclear date. The aims this study were determine whether genes expressed porcine different tissues; expression is...

10.1371/journal.pone.0097342 article EN cc-by PLoS ONE 2014-05-19

Cephalosporin-resistant Vibrio alginolyticus was first isolated from food products, with β-lactamases encoded by blaPER-1, blaVEB-1, and blaCMY-2 being the major mechanisms mediating their cephalosporin resistance. The complete sequence of a multidrug resistance plasmid, pVAS3-1, harboring qnrVC4 genes decoded in this study. Its backbone exhibited genetic homology to known IncA/C plasmids recoverable members family Enterobacteriaceae, suggesting its possible origin Enterobacteriaceae.

10.1128/aac.00300-16 article EN Antimicrobial Agents and Chemotherapy 2016-03-15

Abstract Objectives To characterize the clinical features and outcomes of childhood-onset primary Sjögren’s syndrome (pSS). Methods Patients less than 18 years old who were diagnosed with pSS by paediatric rheumatologists included, all patients applied 2002 American-European Consensus Group (ACEG) criteria, 2016 American College Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria for pSS, or 1999 proposed juvenile criteria. The electronic medical records from 2013 to 2020...

10.1186/s12969-022-00779-3 article EN cc-by Pediatric Rheumatology 2023-01-27

Phthalates have been reported to impair fertility in various studies. However, evidence exploring the associations between phthalate metabolites follicular fluid (FF) and reproductive outcomes is lacking.

10.1289/ehp11998 article EN public-domain Environmental Health Perspectives 2023-12-01

Heat stress (HS) disrupts intestinal microbiota, glycolipid metabolism, and hepatic mitochondrial function in late gestational mice. Baicalin (BAI), a Chinese herbal medicine known for its heat-clearing anti-inflammatory properties, has shown promise modulating microecology mitigating inflammation various organs. This study investigates whether baicalin attenuates HS-induced microbial dysbiosis liver damage pregnant mice during gestation. Twenty-four were randomly assigned to four groups,...

10.1016/j.ecoenv.2024.116832 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2024-08-12

The objective of the current experiment was to explore intestinal microbiota ecological response oral administrations hydrogen-rich water (HRW) and lactulose (LAC) in female piglets fed a Fusarium mycotoxin-contaminated diet. A total 24 individually-housed (Landrace × large white; initial average body weight, 7.25 ± 1.02 kg) were randomly assigned receive four treatments (six pigs/treatment): uncontaminated basal diet (negative control, NC), (MC), MC + HRW (MC HRW), LAC LAC) for 25...

10.3390/toxins10060246 article EN cc-by Toxins 2018-06-16

The effect of concentrate mixtures with crude protein (CP) levels 10%, 13%, 16%, and 19% diets roughage to ratios 80:20, 60:40, 40:60, 20:80 (w/w) were determined on dry matter (DM) organic (OM) digestibility, fermentation metabolites using an in vitro technique. In fermented attributes measured after 4, 24, 48 h incubation respectively. digestibility DM OM, total volatile fatty acid (VFA) increased whereas pH decreased the amount diet (p<0.001), however CP did not have any influence these...

10.5713/ajas.2013.13560 article EN cc-by Asian-Australasian Journal of Animal Sciences 2014-04-24
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