A5034802181- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Ocular Diseases and Behçet’s Syndrome
- Retinal Development and Disorders
- Neurological Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Ophthalmology and Visual Impairment Studies
- Neuropeptides and Animal Physiology
- Vascular Malformations Diagnosis and Treatment
- Corneal surgery and disorders
- Optical Coherence Tomography Applications
- Ocular Oncology and Treatments
- melanin and skin pigmentation
- Metabolomics and Mass Spectrometry Studies
- Acute Ischemic Stroke Management
- Ocular and Laser Science Research
- Child Abuse and Related Trauma
- Advanced Glycation End Products research
- Saffron Plant Research Studies
- Cardiac Health and Mental Health
- Digital Imaging for Blood Diseases
Kyung Hee University
2016-2025
Kyung Hee University Dental Hospital
2013-2023
Kyung Hee University Medical Center
2006-2023
Duke-NUS Medical School
2020
Singapore National Eye Center
2020
Singapore Eye Research Institute
2020
Kangwon National University Hospital
2014-2015
Novartis (South Korea)
2015
Inje University Seoul Paik Hospital
2013
Kangwon National University
2012
To investigate diurnal variations in choroidal thickness (CT) relation to various factors healthy Korean subjects using spectral-domain optical coherence tomography.A prospective study was conducted on 100 volunteers who each underwent measurements of CT the same subfoveal area an enhanced depth imaging technique with tomography at 8 AM, 11 2 PM, and 5 PM. Possible correlations between variation other factors, such as sex, axial length (AL), baseline (8 AM), blood pressure, intraocular were...
To evaluate the correlation between inner retinal layer thinning and foveal microvasculature in type 2 diabetes using optical coherence tomography angiography (OCTA).A cross-sectional study involved 155 diabetic eyes. All patients were divided into two groups based on retinopathy (DR) grade: no DR (NDR, n=80) mild-to-moderate non-proliferative (NPDR, n=75). Foveal avascular zone (FAZ) area, FAZ circularity index, perimeter, vessel density perfusion index of parafoveal perifoveal area...
Diabetic patients with a long disease duration usually accompanied complication such as diabetic retinopathy, but in some had no complication.We analyzed differences plasma metabolites according to the presence or absence of retinopathy (DR) type 2 (T2D) ≥ 15 years.A cohort 183 T2D was established. Their biospecimens and clinical information were collected accordance guidelines National Biobank Korea, Korean Diabetes Association. DR phenotypes subjects verified by ophthalmologic specialists....
In Brief Purpose: To evaluate the visual and morphologic outcomes of intravitreal ranibizumab (IVR) in eyes with diabetic macular edema (DME) based on pattern optical coherence tomography. Methods: A prospective consecutive series 55 DME was classified according to OCT features: diffuse retinal thickening (DRT), cystoid (CME), serous detachment (SRD). Patients received three monthly injections IVR as needed thereafter. The primary outcome number treatments undertaken by type over 12 months....
<i>Aim:</i> To compare the effects of intravitreal bevacizumab on different morphologic patterns diabetic macular edema (DME) classified using optical coherence tomography (OCT). <i>Materials and Methods:</i> Medical records for 65 eyes 48 patients were retrospectively reviewed, each subject was as one three DME types according to OCT features: diffuse retinal thickening (DRT), cystoid (CME), serous detachment (SRD). Subjects given monthly injections (1.25 mg/0.05...
Objective: With the scenario of limited labeled dataset, this paper introduces a deep learning-based approach that leverages Diabetic Retinopathy (DR) severity recognition performance using fundus images combined with wide-field swept-source optical coherence tomography angiography (SS-OCTA). Methods: The proposed architecture comprises backbone convolutional network associated Twofold Feature Augmentation mechanism, namely TFA-Net. former includes multiple convolution blocks extracting...
We evaluated the incidence and risk factors for recurrence in patients with neovascular age-related macular degeneration (nAMD) who discontinued anti-vascular endothelial growth factor (VEGF) therapy under a modified treat-and-extend (TAE) protocol. A retrospective analysis of 68 was conducted. Therapy after extending treatment interval to ≥ 5 months maintaining disease stability 6 months. The TAE protocol included three phases: loading, observation, TAE, initial intervals determined by...
Purpose: To investigate the patterns of fundus autofluorescence (FAF) abnormalities in patients with central serous chorioretinopathy (CSC). Methods: This cross-sectional observational study included 126 eyes 118 who were diagnosed from December 2006 to April 2012 at Kyung Hee University Hospital, Seoul, Korea. Fundus analyzed spectral domain optical coherence tomography and visual acuity. Results: grouped as blocked (38.9%), mottled (8.7%), hyper (31.0%), hyper/hypo (13.5%), or descending...
To evaluate changes in ocular wavefront aberrations and retinal image quality with objective accommodation normal human eyes.Department of Ophthalmology Visual Science, Seoul St. Mary's Hospital, College Medicine, The Catholic University Korea, Seoul, Korea.Cohort study.Healthy emmetropic eyes were measured an iTrace aberrometer while the subjects fixated at far (6.0 m) near (40 cm). Wavefront data analyzed 3.0 mm 5.0 pupil diameters. influence higher-order (HOAs) on was simulated by...
Purpose: Swept-source optical coherence tomography angiography was used to investigate choroidal changes and their association with pigment epithelial detachments (PEDs) in eyes polypoidal vasculopathy (PCV) after treatment vascular endothelial growth factor (VEGF) inhibitors. Methods: Patients treatment-naïve PCV were included underwent anti-VEGF therapy. Mean thickness (MCT), vascularity index (CVI), PED volume measurements obtained before treatment. Results: Thirty-four from 33 patients...
To investigate the pathophysiologic characteristics of diabetic complications, we identified differences in plasma metabolites subjects with type 2 diabetes (T2DM) or without macular edema (DME) and a disease duration > 15 years. An cohort older T2DM patients prolonged was established, clinical information biospecimens were collected following guidelines National Biobank Korea. DME phenotypes by ophthalmologic specialists. For metabolomics studies, propensity matched case control samples...
To evaluate the 2-year efficacy of photodynamic therapy (PDT) combined with intravitreal injection anti-vascular endothelial growth factor (anti-VEGF) in patients polypoidal choroidal vasculopathy (PCV).Twenty-two eyes 22 PCV followed up for ≥24 months after PDT and anti-VEGF combination were retrospectively reviewed. The received (1.25 mg bevacizumab or 0.5 ranibizumab) within 7 days PDT. Eyes retreated injection, only when indicated. Main outcome measures best-corrected visual acuity...
To use spectral-domain optical coherence tomography to evaluate the postoperative retinal nerve fiber layer (RNFL) thickness changes in eyes undergoing vitrectomy.This is a retrospective study of 44 patients (44 eyes) who underwent monocular vitrectomy for an epiretinal membrane (19 eyes), macular hole (12 or vitreous hemorrhage (13 eyes). Quantitative analysis peripapillary RNFL by was performed before surgery and 6 months postoperatively on both eyes.Mean patient age 62.72 ± 9.11 years....
In Brief Purpose: To evaluate the topographic changes in macular ganglion cell–inner plexiform layer (GCIPL) thickness after vitrectomy with indocyanine green–guided internal limiting membrane (ILM) peeling eyes idiopathic hole. Methods: This is a retrospective analysis of 58 consecutive surgically closed hole ILM peeling. Further, 31 that had undergone without were used as control group. The GCIPL was measured spectral domain optical coherence tomography before and at 1 month 6 months...
Purpose: To investigate longitudinal changes and associated factors for microvascular parameters in macula-off rhegmatogenous retinal detachment (RRD) after repair surgery. Methods: This is a retrospective study of 34 eyes with RRD. The foveal avascular zone (FAZ) area parafoveal vessel density were recorded every 3 months 1 year We analyzed × mm 6 swept-source optical coherence tomographic (OCT) angiography images to quantify parameters. Individual clinical pre- postoperative OCT find the...
This study assessed the role of potassium (K + ), magnesium (Mg 2+ and calcium (Ca ) ions in enhanced biological phosphorus removal (EBPR) from wastewaters using a membrane bioreactor (MBR). A linear relationship anaerobic aerobic/anoxic phases for P uptake versus release was obtained known equation Δ = × b, where constants “a” “b” were found to be 0.44 8.40, respectively. Both soluble with phosphate phase, but they accumulated again during successive phase. The correlation coefficients ( R...