- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Genetic Associations and Epidemiology
- Lung Cancer Treatments and Mutations
- Sex and Gender in Healthcare
- Cancer survivorship and care
- Infant Health and Development
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Physical Activity and Health
- Infective Endocarditis Diagnosis and Management
- Cancer Immunotherapy and Biomarkers
- Breastfeeding Practices and Influences
- Child Nutrition and Feeding Issues
- Cardiovascular Effects of Exercise
- Lymphatic System and Diseases
- Cancer Genomics and Diagnostics
- Diet and metabolism studies
- Growth Hormone and Insulin-like Growth Factors
- Birth, Development, and Health
Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025
Université Laval
2010-2024
Institut Universitaire de Cardiologie et de Pneumologie de Québec
2010-2024
Lung Institute
2019
Abstract Background and Aims Physical activity has proven effective in preventing atherosclerotic cardiovascular disease, but its role degenerative valvular heart disease (VHD) remains uncertain. This study aimed to explore the dose–response association between moderate vigorous physical (MVPA) volume risk of VHD among middle-aged adults. Methods A full week accelerometer-derived MVPA data from 87 248 UK Biobank participants (median age 63.3, female: 56.9%) 2013 2015 were used for primary...
Objective To explore the association of wearable device-measured moderate-to-vigorous intensity physical activity (MVPA) with cardiovascular disease (CVD) risk in long-term cancer survivors. Methods This retrospective analysis involved a prospective cohort 6109 survivors without CVD from UK Biobank accelerometry subsample. The MVPA volume is categorised into four groups based on guideline recommendations (0–75 min/week, 75–150 150–300 ≥300 min/week). Cox proportional hazard models are used...
The insulin/IGF-1 signaling pathway is a determinant of aging and age-related diseases. IGF-binding protein 2 (IGFBP2) secreted by white adipocytes contributes to the prevention diet-induced obesity insulin resistance in mice. However, expression levels IGFBP2 disorders have not been evaluated. present study was aimed at determining mRNA adipose tissue conditions such as obesity. In visceral (WAT), but subcutaneous WAT, were significantly lower obese ob/ob, db/db high fat-fed mice compared...