- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Infrared Thermography in Medicine
- Advanced Image Fusion Techniques
- Advanced MRI Techniques and Applications
- Image and Signal Denoising Methods
- Thermography and Photoacoustic Techniques
- Surgical Simulation and Training
- Brain Tumor Detection and Classification
- Animal Nutrition and Physiology
- Radiation Dose and Imaging
- Intraoperative Neuromonitoring and Anesthetic Effects
- Machine Learning in Materials Science
- Neuroscience and Neural Engineering
- Livestock and Poultry Management
- Animal Genetics and Reproduction
- Meningioma and schwannoma management
University Hospital Carl Gustav Carus
2020-2025
TU Dresden
2012-2025
Abstract The in ovo sexing of chicken eggs is a current task and prerequisite to overcome the mass killing male day-old chicks from laying lines. Although various methods have been developed tested recent years, practicable for sex determination are still missing which can be applicated poultry hatcheries before embryo capable nociception pain sensation. Optical spectroscopic enable an early sex. In this study, novel method based on two-wavelength fluorescence excitation described. More than...
The precise identification and preservation of functional brain areas during neurosurgery are crucial for optimizing surgical outcomes minimizing postoperative deficits. Intraoperative imaging plays a vital role in this context, offering insights that guide surgeons protecting critical cortical regions. We aim to evaluate compare the efficacy intraoperative thermal (ITI) optical (IOI) detecting primary somatosensory cortex, providing detailed assessment their potential integration into...
Intraoperative optical imaging (IOI) is a localization method for functional areas of the human brain cortex during neurosurgical procedures. The aim current work was to develop new analysis technique computation two-dimensional IOI activity maps that suited especially use in clinical routine. includes stimulation scheme comprises 30-s rest and conditions, connection with pixelwise spectral power map calculation. A software phantom used verification implemented algorithms as well comparison...
Intraoperative optical imaging (IOI) is a marker-free, contactless, and noninvasive technique that able to visualize metabolic changes of the brain surface following neuronal activation. Although it has been used in past mainly for identification functional areas under general anesthesia, authors investigated potential method during awake surgery. Measurements were performed 10 patients who underwent resection lesions within or adjacent cortical language motor sites. IOI was applied 3...
Abstract Alterations within cerebral hemodynamics are the intrinsic signal source for a wide variety of neuroimaging techniques. Stimulation specific functions leads due to neurovascular coupling, changes in regional blood flow, oxygenation and volume. In this study, we investigated temporal characteristics cortical hemodynamic responses following electrical, tactile, visual, speech activation different stimulation paradigms using Intraoperative Optical Imaging (IOI). Image datasets from...
Abstract Brain tumor resection is even today one of the most challenging disciplines in neurosurgery. The current state art for identification tissue during surgical procedure comprises a wide variety different tools, each with its own limitations and drawbacks. In this paper, we present novel approach, use optical imaging connection direct electrical cortical stimulation (DCS), impaired functional intact normal brain under intraoperative conditions. Measurements an setup were performed as...
Abstract The determination of exact tumor boundaries within eloquent brain regions is essential to maximize the extent resection. Recent studies showed that intraoperative optical imaging (IOI) combined with median nerve stimulation a helpful tool for visualization primary sensory cortex (PSC). In this technical note, we describe novel approach using IOI painless tactile irritation demonstrate feasibility topographic mapping different body PSC. addition, compared results preoperative...
Abstract Intraoperative Optical Imaging (IOI) is a neuro-imaging technique that allows the visualization of changes in optical properties brain cortex. Recent developments enhanced method regarding robustness under intraoperative conditions. However, necessity additional hardware still limits use operating room (OR). Since modern surgical microscopes are potentially equipped with all required for imaging, we investigated possible such standard RGB camera IOI. Measurements were performed on...
Multimodal medical image fusion helps in combining contrasting features from two or more input imaging modalities to represent fused information a single image. One of the pivotal clinical applications is merging anatomical and functional for fast diagnosis malignant tissues. In this paper, we present novel end-to-end unsupervised learning-based Convolutional Neural Network (CNN) fusing high low frequency components MRI-PET grayscale pairs, publicly available at ADNI, by exploiting...
The success of brain surgery depends on the exact and effective treatment pathological alterations while preserving functional tissue essential vessels. Varying intraoperative imaging methods have been developed to achieve this goal. For cortical perfusion imaging, application time-resolved thermography in combination with an intravenously applied cold bolus became a promising approach. This work provides regularized semiparametric regression framework that detects signal response function...
In this paper, a method is presented to estimate and correct pulse breathing motion artifacts of infrared (IR) brain images while preserving all-important image information. First, complex steerable pyramid carried out decompose the sequence separate amplitude from their phase. Second, finite impulse response (FIR) filter employed selected frequency bands at each scale orientation followed by reconstructing with corresponding amplitudes. Third, optical flow applied only. Fourth, bicubic...
In this paper, we propose a novel method for image registration and fusion of Infrared Thermography (IRT) visible light brain images. Firstly, introduce by employing preprocessing to bring both images similar level followed similarity transformation which consists translations, rotation, isometric scaling. To address the curved shape human within image, multiresolution Demons is carried out. Furthermore, method, Multiscale Decomposition (MSD) based on Rolling Guidance Filter (RGF) with...