Object Intraoperative optical imaging (IOI) is an experimental technique used for visualizing functional brain areas after surgical exposure of the cerebral cortex. This identifies local changes in blood volume and oxygenation caused by stimulation specific functions. The authors describe a new IOI method, including innovative data analysis, that can facilitate intraoperative on routine basis. To evaluate reliability validity this approach, they method to demonstrate visualization median...

Multi-touch surfaces are predestined to be used by many users at the same time. However, most systems not able distinguish touches of different users. This paper presents ongoing work on using wristbands, equipped with infrared LEDs, provide identities. The LEDs transmit coded light pulses as an identifier. We a specific blinking-pattern determine orientation wristband in order reliably associate corresponding touches.

Intraoperative optical imaging of intrinsic signals can improve the localization functional areas cortex. On basis a review current state technology, setup was developed and evaluated. The aim to implement an easy-to-use robust that be used in clinical routine with standard hardware equipment (surgical microscope, high-resolution camera, stimulator for peripheral nerve stimulation) custom-made software intraoperative postoperative data analysis. Evaluation different light sources (halogen,...

Intraoperative optical imaging (IOI) is a localization method for functional areas of the human brain cortex during neurosurgical procedures. The aim current work was to develop new analysis technique computation two-dimensional IOI activity maps that suited especially use in clinical routine. includes stimulation scheme comprises 30-s rest and conditions, connection with pixelwise spectral power map calculation. A software phantom used verification implemented algorithms as well comparison...

Multimodal medical image fusion combines information of one or more images in order to improve the diagnostic value. While previous applications mainly focus on merging from computed tomography, magnetic resonance imaging (MRI), ultrasonic and single-photon emission we propose a novel approach for registration preoperative 3D MRI with intraoperative 2D infrared thermography. Image-guided neurosurgeries are based neuronavigation systems, which further allow us track position orientation...

Intraoperative optical imaging (IOI) is a method to visualize functional activated brain areas during surgery using camera system connected standard operating microscope. Three different high-resolution systems (Hamamatsu EB-CCD C7190-13W, Hamamatsu C4742-96-12G04, and Zeiss AxioCam MRm) have been evaluated for suitability detect by detecting stimulation-dependent blood volume changes in the somatosensory cerebral cortex after median nerve stimulation. The image quality of was 14 patients...

Intraoperative optical imaging (IOI) is a marker-free, contactless, and noninvasive technique that able to visualize metabolic changes of the brain surface following neuronal activation. Although it has been used in past mainly for identification functional areas under general anesthesia, authors investigated potential method during awake surgery. Measurements were performed 10 patients who underwent resection lesions within or adjacent cortical language motor sites. IOI was applied 3...

Several functional brain imaging and mapping techniques have been used for the intraoperative identification preservation of sensory, motor, speech areas brain. However, monitoring visual function is less frequently performed in clinical routine. To our knowledge, here we demonstrate first time that individual cortex can be mapped to surface using a contact-free optical camera system during surgery. Intraoperative (IOI) was by stimulation both eyes stobe-light flashes. Images were acquired...

Ultrasound can visualize and update the vessel status in real time during cerebral vascular surgery. We studied depiction of parent vessels aneurysms with a high-resolution 3D intraoperative ultrasound imaging system aneurysm clipping using rotational digital subtraction angiography as reference.We analyzed 39 patients to intraoperatively nearby tree before after clipping. Simultaneous coregistration preoperative data was performed verify anatomical assignment.Intraoperative detected 35 43...

Recently, endoscopic high-speed laryngoscopy has been established for commercial use as a state-of-the-art technique to examine vocal fold kinematics. Since modern cameras provide sampling rates of several thousand frames per second, high volume data be considered visual and objective analysis. A method visualizing speed videos in three-dimensional cycle-based graphs combining extending the approaches phonovibrograms electroglottographic wavegrams is presented. To build phonovibrographic...

Present methods for quantitative measurement of cerebral perfusion during neurosurgical operations require additional technology measurement, data acquisition, and processing. This study used conventional fluorescence video angiography – as an established method to visualize blood flow in brain vessels enhanced by a quantifying software tool. For these purposes, the dye indocyanine green is given intravenously, after activation near-infrared light source signal recorded. Video are analyzed...

Abstract Brain tumor resection is even today one of the most challenging disciplines in neurosurgery. The current state art for identification tissue during surgical procedure comprises a wide variety different tools, each with its own limitations and drawbacks. In this paper, we present novel approach, use optical imaging connection direct electrical cortical stimulation (DCS), impaired functional intact normal brain under intraoperative conditions. Measurements an setup were performed as...

Non-linear multi-contrast microscopy or how it is often called multimodal imaging features molecular contrast, because the combination of coherent anti-Stokes Raman scattering (CARS), second harmonic generation (SHG) and two-photon-excited fluorescence (TPEF). The application this techniques for biological tissue straight forward, which reason to investigate diagnostics based on imaging. To do so, needs be combined with image analysis methods. perform such an images in a reliable robust...

Mechanical stimulation has been shown to impact the properties of engineered hyaline cartilage constructs and is relevant for engineering osteochondral tissues. Most mechanical stimulators developed date emphasize precision over adaptability standard tissue culture equipment protocols. The realization characteristics in approaching native requires optimization complex variables (type stimulus, regimen, bimolecular signals). We have proposed validated a stimulator design that focuses on high...

Radiopharmaceuticals have been used for the treatment of various forms cancer since 1940s. In recent years, advantages alpha emitting radionuclides emerged as a favourable option. However, most long decay chains with long-lived daughter radionuclides. This leads to uncertainties in dosimetry normal organs and tissues, when established models are employed. The aim this project is assign each progeny its own biokinetic behaviour. novel model was applied 223Ra-dichloride, frequently patients...

Early identification of frailty by clinical instruments or accumulation deficit indexes can contribute to improve healthcare for older adults, including the prevention negative outcomes in acute care. However, conflicting evidence exists on how best capture this setting. Simultaneously, increasing utilisation electronic health records (EHRs) opens up new possibilities research and patient care, frailty.The Swiss Frailty Network Repository (SFNR) primarily aims develop an Index (eFI) from...

A demonstrator system for planning neurosurgical procedures was developed based on commercial hardware and software. The combines an easy-to-use environment surgical with high-end visualization the opportunity to analyze data sets research purposes. is software AMIRA. Specific algorithms segmentation, elastic registration, have been implemented adapted clinical workflow. Modules from AMIRA image processing library Insight Segmentation Registration Toolkit (ITK) can be combined solve various...

Smart insoles, often based on printed electronics, are today state of the art diagnosis tools for gait analysis. In this work, we present potential use smart insoles in field diabetes diagnostics. We compare two shoe foot temperature, one fully printed, other built using discrete NTC foil, both capable achieving a temperature accuracy below 0.5°C. Temperature profiles measured, achievable and applicability ulcers prevention discussed. Beside manufacturing concept, calibration in-situ insole...

Abstract Introduction Nasal alar defects pose significant challenges due to the nose's central role in facial aesthetics and function. Various causes, including skin cancer resection, necessitate effective reconstruction techniques. Despite several available methods, identifying an ideal approach remains elusive. Methods This study introduces a single‐stage technique employing nasolabial‐folded‐flap (NFL) with conchal cartilage support. A structured patient questionnaire evaluated functional...