A5065130900- Hearing Loss and Rehabilitation
- Neuroscience and Music Perception
- Hearing, Cochlea, Tinnitus, Genetics
- Multisensory perception and integration
- Visual perception and processing mechanisms
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 detection and testing
- Otolaryngology and Infectious Diseases
- Infection Control and Ventilation
- COVID-19 and Mental Health
- Tracheal and airway disorders
- Respiratory viral infections research
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 and COVID-19 Research
- Acoustic Wave Phenomena Research
- Trauma Management and Diagnosis
- Foreign Body Medical Cases
- Infectious Diseases and Tuberculosis
- Ear Surgery and Otitis Media
- Noise Effects and Management
- Axon Guidance and Neuronal Signaling
- COVID-19 and healthcare impacts
- Angiogenesis and VEGF in Cancer
- Streptococcal Infections and Treatments
Helsinki University Hospital
2021-2024
University of Helsinki
2021-2024
University of Colorado Boulder
2020-2023
University of Colorado System
2020
Aalto University
2012-2014
Sigrid Jusélius Foundation
2000
Abstract We report the first long-term follow-up of a randomized trial (NCT04978259) addressing effects remdesivir on recovery (primary outcome) and other patient-important outcomes one year after hospitalization resulting from COVID-19. Of 208 patients recruited 11 Finnish hospitals, 198 survived, whom 181 (92%) completed follow-up. At year, self-reported occurred in 85% 86% standard care (SoC) (RR 0.94, 95% CI 0.47-1.90). infer no convincing difference between SoC quality life or symptom (...
ported increased ICG uptake in surrounding tissues, such as the thyroid, thymus, and lymph nodes, 5 making findings of 2 ectopic parathyroid glands thymus tissue by Kennedy et al 1 promising for this technique.The advancements made authors identification may be a result incremental improvements NIR imaging devices or experience team with optimal dosing window.Various groups have shown that these components influence performance across various tumor types intraoperative agents. 6 While...
In rodents, the Robo1 gene regulates midline crossing of major nerve tracts, a fundamental property mammalian CNS. However, neurodevelopmental function human ROBO1 remains unknown, apart from suggested role in dyslexia. We therefore studied axonal with functional approach, based on magnetoencephalography, 10 dyslexic individuals who all share same rare, weakly expressing haplotype gene. Auditory-cortex responses were recorded separately to left- and right-ear sounds that amplitude modulated...
Auditory steady-state responses that can be elicited by various periodic sounds inform about subcortical and early cortical auditory processing. Steady-state to amplitude-modulated pure tones have been used scrutinize binaural interaction frequency-tagging the two ears' inputs at different frequencies. Unlike tones, speech music are physically very complex, as they include many frequency components, pauses, large temporal variations. To examine utility of magnetoencephalographic (MEG) fields...
Abstract In patients with acute epiglottitis, the possibility of COVID‐19 should be ruled out. Repeated nasofiberoscopy examinations or a tracheostomy, which may produce infectious aerosols, required.
Most right-handers perceive an octave illusion when they are presented with a 400 Hz tone to one ear and 800 the other simultaneously, tones continuously reverse between ears: instead of correct sound sequence, subjects typically report high in right alternating low left. To study neural basis illusion, we recorded neuromagnetic responses binaural different combinations. In auditory cortex each hemisphere, 100 ms response (N100m) was stronger pairs where contralateral ipsilateral than vice...
Background/Objectives: This register study elucidates the national trends in otolaryngologic surgery volume Finland over a ten-year period. In particular, we investigated whether pandemic, which had marked effect on communicable diseases, an impact infection-related ear, nose, and throat (ENT) procedures. For reference, used noninfectious ENT Methods: The data of this consisted volumes different otolaryngological surgical procedures from 2012 to 2022. A linear regression model was applied...
The auditory octave illusion arises when dichotically presented tones, one apart, alternate rapidly between the ears. Most subjects perceive an illusory sequence of monaural tones: A high tone in right ear (RE) alternates with a low tone, incorrectly localized to left (LE). Behavioral studies suggest that perceived pitch follows RE input, and location higher-frequency sound. To explore link pitches brain-level interactions dichotic magnetoencephalographic responses were recorded 4 binaural...
Bilateral cochlear implantation is increasing worldwide. In adults, bilateral implants (BICI) are often performed sequentially with a time delay between the first (CI1) and second (CI2) implant. The benefits of BICI have been reported for well over decade. This study aimed at investigating these consecutive sample adult patients. Improvements in speech-in-noise recognition after CI2 were followed up longitudinally 12 months internationally comparable Finnish matrix sentence test. test scores...
A significant portion of hearing-impaired children have additional disabilities, but data about the maturation their auditory cortex are scarce. In these children, behavioral tests often unreliable, and objective needed for diagnostics follow-up. This study aimed to explore cortical language development, usability an electroencephalogram-based biomarker in with multiple disabilities. 65 hearing aid cochlear implant users (36 females; 36 disabilities; 44.3 ± 18.5 months age, mean SD),...
A narrow bony cochlear nerve canal (BCNC), as well a hypoplastic and aplastic (CN) have been associated with increased electrically-evoked compound action potential (eCAP) thresholds in some studies, suggesting poorer neural excitability implantation. Also, large cochleae the extent of activated spiral ganglion neurons electrical stimulation is less than smaller ones. However, detailed description relationship between eCAP for lateral-wall electrode array dimensions inner-ear structures...
To assess the extent of staff exposure to aerosol generation in common pediatric otorhinolaryngological procedures (tonsillotomies, adenoidectomies, and tympanostomies) determine surgical phases responsible for most these procedures.
Isolation precautions are essential prevent spread of COVID-19 infection but may have a negative impact on inpatient care. The these measures non-COVID-19 patients remains largely unexplored. This study aimed to investigate diagnostic and treatment delays related isolation precautions, the associated patient outcome, predisposing risk factors for delays. observational was conducted in seven Helsinki region hospitals during first wave pandemic Finland. used data all inpatients, who were...
Foreign bodies cause a remarkable number of otolaryngological emergency visits and occasionally result in life-threatening conditions later-emerging complications. Patient recovery depends on the detection proper extraction all foreign materials. Despite various obtainable diagnostic tools, adequate anamnesis forms basis clinical reasoning should direct later examinations radiological imaging. This case report describes challenging patient with unique trauma mechanism: many pieces fragmented...