A5004561441- Tracheal and airway disorders
- Intensive Care Unit Cognitive Disorders
- Neonatal Respiratory Health Research
- Central Venous Catheters and Hemodialysis
- Congenital Diaphragmatic Hernia Studies
- Family and Patient Care in Intensive Care Units
- Disaster Response and Management
- Healthcare Decision-Making and Restraints
- Patient Satisfaction in Healthcare
- Dysphagia Assessment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Immune cells in cancer
- Healthcare Policy and Management
- Tissue Engineering and Regenerative Medicine
- Global Health Care Issues
- Alcoholism and Thiamine Deficiency
- Palliative Care and End-of-Life Issues
- Urinary Tract Infections Management
- Esophageal and GI Pathology
- Anesthesia and Sedative Agents
- Streptococcal Infections and Treatments
- COVID-19 and healthcare impacts
- Emergency and Acute Care Studies
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
Oregon Medical Research Center
2024
New York Proton Center
2024
University of Pittsburgh
2024
Communities In Schools of Orange County
2024
Lindsay Unified School District
2024
University of Iowa Hospitals and Clinics
2023
Murphy Oil Corporation (United States)
2022
Brigham and Women's Hospital
2022
Thrombolysis in Myocardial Infarction Study Group
2022
Harvard University
2022
To further examine the half-life of alveolar macrophages, chimeric CD 45.2 mice were generated through bone marrow transplantation donor 45.1 cells. Before administration cells, recipient divided into two cohorts: first cohort received total body irradiation; second also irradiation-however, thorax, head, and upper extremities shielded with lead. Flow cytometric analysis was then performed on blood, peritoneal, bronchoalveolar lavage cells over time to quantify engraftment. The data for...
The efficacy and safety of prophylactic full-dose anticoagulation antiplatelet therapy in critically ill COVID-19 patients remain uncertain.COVID-PACT (Prevention Arteriovenous Thrombotic Events Critically-ill Patients Trial) was a multicenter, 2×2 factorial, open-label, randomized-controlled trial with blinded end point adjudication intensive care unit-level COVID-19. were randomly assigned to strategy or standard-dose anticoagulation. Absent an indication for therapy, additionally either...
Contained within the adult lung are differentiated mesenchymal cell types (cartilage, smooth muscle, and myofibrobasts) that provide structural support for airways vessels. Alterations in number phenotype of these cells figure prominently pathogenesis a variety diseases. While thought to arise locally, progenitors have yet be purified. In previous work, we developed method isolating from tissue: this technique takes advantage unique ability populations enriched somatic stem progenitor...
Catheter-associated urinary tract infections (CAUTIs) represent approximately 9% of all hospital acquired infections, and 65%–70% CAUTIs are believed to be preventable. In the spring 2013, Boston Medical Center (BMC) began an initiative decrease CAUTI rates within its intensive care units (ICUs). A taskforce convened reviewed process maps gap analyses. Based on Centers for Disease Control Prevention (CDC) Institute Healthcare Improvement (IHI) guidelines, delineated by Infection Practices...
Rationale: Several institutions have implemented phenobarbital-based pathways for the treatment of alcohol withdrawal syndrome (AWS). However, little is known about care processes, effectiveness, and safety intensive unit (ICU) patients. Objectives: To examine clinician acceptability feasibility patient outcomes after implementation a pathway medical ICU (MICU) patients with severe AWS. Methods: We conducted mixed-method study quality-improvement intervention designed to improve workflow...
This quality improvement initiative sought to develop a sedation vacation (SV) protocol increase SV performance and ensure sustainability. A standardized, nurse-driven within the electronic medical record was implemented in adult intensive care units (ICUs) at Boston Medical Center. For 6 months, data were collected on number of assessments performed, completion, eligibility, reason for exclusion. Secondary outcomes included ICU length stay (LOS) ventilator LOS. Of 1730 patient-days during...
The coronavirus disease 2019 pandemic has overwhelmed healthcare resources even in wealthy nations, necessitating rationing of limited without previously established crisis standards care protocols. In Massachusetts, triage guidelines were designed based on acute illness and chronic life-limiting conditions. this study, we sought to retrospectively validate protocol cohorts critically ill patients from our hospital.We applied hospital-adopted guidelines, which defined severe major conditions...
Introduction: A multidisciplinary, quality improvement (QI) group was established to develop a standardized process for the administration of daily interruptions sedation (DIS). The purpose this study compare effects intervention historical cohort. Methods: multidisciplinary QI developed protocol, consolidated continuous sedative orders into an order set, and created task in electronic medical record prompt nurse conduct DIS eligible patients. initiative piloted single adult MICU from...