A5070622110- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Aortic Disease and Treatment Approaches
- Traumatic Brain Injury and Neurovascular Disturbances
- Coronary Interventions and Diagnostics
- Vascular Malformations Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Acute Ischemic Stroke Management
- Metamaterials and Metasurfaces Applications
- Acoustic Wave Phenomena Research
- Lipoproteins and Cardiovascular Health
- Electromagnetic Scattering and Analysis
- Aortic aneurysm repair treatments
- Advanced MRI Techniques and Applications
- Moyamoya disease diagnosis and treatment
- Neurosurgical Procedures and Complications
- Advanced Materials and Mechanics
- Protease and Inhibitor Mechanisms
Washington University in St. Louis
2020
Objective Fractional flow (FF) reserve has been developed as a gold standard for coronary intervention. Intracranial FF is also valuable hemodynamic index to assess the severity of narrowing in intracranial atherosclerotic stenosis (ICAS). This study aims investigate predictive value assessing restenosis following endovascular treatment patients with symptomatic ICAS. Methods retrospective recruited 67 ICAS who received stenting between March 2019 and January 2024. was measured by dedicated...
Fractional flow reserve is widely used for the functional evaluation of coronary artery stenosis. Some studies have similarly translesional pressure ratio measurements intracranial atherosclerotic In this paper, we aimed to investigate relationship between and cerebral tissue perfusion by MR imaging provided a non-invasive method evaluating significance stenosis.A total 18 consecutive patients with stenosis including 19 stenotic vessels were recruited. The was measured using guidewire,...
Background: To date, PCSK9 inhibitors are well known for eliminating cardiac and cerebral artery ischemia events by lowering the serum lipid level. However, pathophysiological value of in-plaque expression is still unclear. Methods: Advanced plaques removed carotid endarterectomy were sectioned stained to identify pattern its co-expression with rupture-relevant markers. investigate correlation regional blood shear flow, hemodynamic characteristics analyzed using computational fluid dynamics,...
High-resolution magnetic resonance imaging (HR-MRI) can provide valuable insights into the evaluation of vascular pathological conditions, and 3D digital subtraction angiography (3D-DSA) offers clear visualization morphology hemodynamics. This study aimed to investigate potential a multimodal method treat unruptured vertebral artery dissection aneurysms (u-VADAs) by fusing image data from HR-MRI 3D-DSA. observational enrolled 5 patients diagnosed with u-VADAs, who were scheduled for...
This study comparatively analyzed the hemodynamic changes resulting from various simulated stent-assisted embolization treatments to explore an optimal treatment strategy for intracranial vertebral artery fusiform aneurysms. An actual aneurysm case treated by large coil post-stenting (PLCS) was used as a control. A single of underwent preoperative and eight postoperative finite element simulations: PLCS [single dual Low-profile Visualized Intraluminal Support (LVIS)], Jailing technique...
Silent MR angiography (silent MRA) is a new generation of non-contrast enhanced with outstanding advantages in visualizing cerebrovascular lesions and the follow-up after endovascular treatment for intracranial aneurysms (IAs). This study aims to investigate reliability silent MRA-based three-dimensional (3D) geometric description hemodynamic calculation IAs.19 patients 23 unruptured IAs, who underwent both MRA 3D rotational (3DRA), were included this study. Computational fluid dynamics...
To analyze how wall enhancement affects hemodynamics and cerebral ischemic risk factors in vertebrobasilar non-saccular intracranial aneurysms (VBNIAs).Ten consecutive were collected, including three transitional dolichoectasia (TVBD). A model was quantitatively constructed to interacts with factors.Enhanced area revealed low shear stress (WSS) gradient (WSSG), high oscillatory index (OSI), relative residence time (RRT), number (GON) while the vortex slow flow region fusiform are similar...
Background and purpose A notable prevalence of subarachnoid hemorrhage is evident among patients with anterior choroidal artery aneurysms in clinical practice. To evaluate the risk rupture unruptured aneurysms, we conducted a comprehensive analysis factors subsequently developed two nomograms. Methods total 120 cases (66 54 ruptured) from 4 medical institutions were assessed utilizing computational fluid dynamics (CFD) digital subtraction angiography (DSA). The training set, consisting 98 3...
Background The aim of this study is to assess the feasibility identifying hemodynamic status intracranial atherosclerotic stenosis (ICAS) using angio-based fractional flow (FF) calculated from a single angiographic view, with wire-based FF as reference standard. Method retrospectively recruited 100 ICAS patients who underwent pressure wire measurement and digital subtraction angiography. AccuICAD software was used calculate FF, wire-measured value serving standard for evaluating accuracy,...
This study compared 2 representative cases with ruptured aneurysms to explore the role of hemodynamic and morphological parameters in evaluating rupture risk intracranial (IAs).
Abstract Background It is still a challenge to choose the most appropriate endovascular treatment strategy for intracranial aneurysms. In this study, we aimed investigate application of AneuPlan™, based on computational fluid dynamics analysis, in surgical planning Methods: 9 patients with aneurysm were enrolled, whose was made according Surgical Planning Program before treatment. Clinical characteristics, procedural details, stimulated hemodynamics analysis after surgery, site effect and...
Introduction Posterior communicating artery (Pcom) aneurysm has unique morphological characteristics and a high recurrence risk after coil embolization. This study aimed to evaluate the relationship between recurrence-related morphology hemodynamics. Method A total of 20 patients with 22 Pcom aneurysms from 2019 2022 were retrospectively enrolled. The parameters measured. hemodynamic simulated based on finite element analysis computational fluid dynamics. differences before treatment caused...
The goal of this paper is to introduce and evaluate the potential a hydrodynamic metamaterial cloak for drag reduction objects in viscous flow. In paper, cloaks 2D complex shapes such as airfoil are created by coordinate transformation using Stokes equations low Reynolds number flows. First, viscosity tensor circular cylinder derived based on equations. Then tensors an elliptic-cylinder obtained stretching cloak. effect simulated commercially available software ANSYS FLUENT 2019R2. By...