A5012329439- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Organ and Tissue Transplantation Research
- Viral Infections and Immunology Research
- Organ Transplantation Techniques and Outcomes
- Cardiac Arrest and Resuscitation
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Issues in Pregnancy
- Renal Transplantation Outcomes and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Oral microbiology and periodontitis research
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Dental Erosion and Treatment
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Dental Health and Care Utilization
- Cardiac electrophysiology and arrhythmias
- Orthopedic Surgery and Rehabilitation
- Contact Dermatitis and Allergies
- Cardiac Ischemia and Reperfusion
Zhejiang Chinese Medical University
2025
Queen's University
2023-2024
University of Washington
2020-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
University of California, San Francisco
2020-2023
Cedars-Sinai Smidt Heart Institute
2015-2020
Cedars-Sinai Medical Center
2012-2020
Procter & Gamble (United States)
2015-2017
Richard Wolf (Germany)
2015
Dartmouth College
2014
The endomyocardial biopsy (EMB) is considered the gold standard in rejection surveillance post cardiac transplant, but invasive, with risk of complications. A previous trial suggested that gene expression profiling (GEP) blood test was noninferior to EMB between 6 and 60 months transplant. As most rejections occur first months, we conducted a single-center randomized GEP versus starting at 55 days transplant (when valid).Sixty heart patients meeting inclusion criteria were beginning either...
Objective Fractional flow (FF) reserve has been developed as a gold standard for coronary intervention. Intracranial FF is also valuable hemodynamic index to assess the severity of narrowing in intracranial atherosclerotic stenosis (ICAS). This study aims investigate predictive value assessing restenosis following endovascular treatment patients with symptomatic ICAS. Methods retrospective recruited 67 ICAS who received stenting between March 2019 and January 2024. was measured by dedicated...
Huntington's disease (HD) is a fatal inherited neurodegenerative disorder. HD caused by polyglutamine expansions in the huntingtin (htt) protein that result neuronal loss and contribute to pathology. The mechanisms of are elusive, there no therapy alleviate HD. To find small molecules slow HD, we screened 1,040 biologically active identify suppressors cell death culture model We found inhibitors mitochondrial function or glycolysis rescued this vivo models. These prevented activating...
Abstract For Interagency Registry for Mechanically Assisted Circulatory Support profiles 1 and 2 cardiogenic shock patients initially placed on extracorporeal membrane oxygenation (ECMO), whether crossover to more durable devices is associated with increased survival, its optimal timing, are not established. Profiles mechanical support were prospectively registered. Survival successful hospital discharge compared between ECMO only, early crossover, delayed crossover. of directly implanted...
Antithymocyte globulin (ATG) is used as induction therapy after cardiac transplant for enhancing immunosuppression and delaying the initiation of nephrotoxic drugs. It unknown if ATG associated with decreased coronary plaque progression by intravascular ultrasound (IVUS).Patients transplanted between March 2010 December 2012 baseline 1-year IVUS were included. All patients included in a secondary analysis. Change was measured blinded fashion on matched segments contrasted induced those who...
Temporary mechanical circulatory support (MCS) can be a bridge to decision for patients in severe cardiogenic shock who may eligible durable or transplantation. Outcomes with Impella microaxial devices salvage of the end-stage heart failure population are not well described. Patients underwent placement as decision, MCS, transplantation were included. Eighty (2.5 [1.3%], CP [53.8%], and 5.0 [45.0%]) placed 64 patients. Implant age was 56.2 ± 12.5 years. Mean duration assisted 13.2 15.1 days,...
Background Percutaneous coronary intervention (PCI) with bare‐metal and first‐generation drug‐eluting stents (DES) for cardiac allograft vasculopathy (CAV) is associated unexpectedly high restenosis rates target lesion revascularization (TLR). Long‐term outcomes of stenting CAV using second‐generation everolimus‐eluting (EES) are not established. Objective To evaluate clinical angiographic EES. Methods Patients who underwent PCI EES were studied. Surveillance angiography was performed at...
Mitral annular calcification (MAC) negatively influences outcomes in surgical mitral valve (MV) repair for regurgitation (MR). However, there are no data on whether MAC impacts of MitraClip percutaneous MV edge-to-edge repair. This study sought to investigate the presence procedural success and durability transcatheter MR using MitraClip.One hundred seventy-three patients undergoing significant were studied. Patients with moderate-or-severe (n=28) compared those no-or-mild MAC....
The purpose of this study was to develop a three-dimensional (3D) motion analysis based anatomical wrist joint coordinate system for measurement in-vivo kinematics. convergent validity and reliability the 3D implementation quantified compared with manual electrogoniometry techniques on 10 cadaveric specimens. Fluoroscopic measurements were used as reference. (mean absolute difference [MAD] = 3.6°) significantly less different (P < .005) than goniometry (MAD 5.7°) but not .066, power 0.45)...