A5021448431- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Diet and metabolism studies
- Organ Donation and Transplantation
- Sodium Intake and Health
- Patient Dignity and Privacy
- Cholesterol and Lipid Metabolism
- Ethics in medical practice
- Medical Malpractice and Liability Issues
- Acute Kidney Injury Research
- Dietetics, Nutrition, and Education
- Kidney Stones and Urolithiasis Treatments
- Palliative Care and End-of-Life Issues
- Hormonal Regulation and Hypertension
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- Potassium and Related Disorders
- Pediatric Urology and Nephrology Studies
- Renal function and acid-base balance
- Blood Pressure and Hypertension Studies
- Healthcare Systems and Technology
- Hospital Admissions and Outcomes
- Renal Transplantation Outcomes and Treatments
- Porphyrin Metabolism and Disorders
- Intestinal and Peritoneal Adhesions
University of Rochester Medical Center
2011-2025
University of Rochester
2008-2024
New York University
2019
Seton Hall University
2019
Wake Forest University
2008
Strong Memorial Hospital
2006
University of Colorado Health
2001-2005
University of Colorado Anschutz Medical Campus
2001-2005
Denver VA Medical Center
2005
Obesity and metabolic syndrome are associated with glomerulosclerosis proteinuria, but the mechanisms not known. The purpose of this study was to determine if there is altered renal lipid metabolism increased expression sterol regulatory element-binding proteins (SREBPs) in a model diet-induced obesity. C57BL/6J mice that were fed high fat, 60 kcal % saturated (lard) fat diet (HFD) developed obesity, hyperglycemia, hyperinsulinemia compared those low 10 (LFD). In contrast, A/J resistant when...
This study investigated the association of intra-abdominal adhesions with risk peritoneal dialysis (PD) catheter complications. Individuals undergoing laparoscopic PD insertion were prospectively enrolled from eight centers in Canada and United States. Patients grouped based on presence observed during insertion. The primary outcome was composite never starting, termination PD, or need for an invasive procedure caused by flow restriction abdominal pain. Seven hundred fifty-eight individuals...
Whole-food plant-based diets (WFPBDs) are beneficial in managing hypertension the general population but have not been well studied chronic kidney disease (CKD), potentially due to concerns about hyperkalemia. We hypothesized that individuals with CKD 3 or 4 attending a 15-day WFPBD education program would achieve lower blood pressure compared those who did not, without an increased risk of This was pilot trial 40 subjects mild-to-moderate and diabetes proteinuria from single academic...
Sterol regulatory element binding proteins (SREBP) are major regulators of fatty acid and cholesterol synthesis. This study found that age-related renal matrix deposition proteinuria were associated with increased expression SREBP-1 SREBP-2 accumulation triglyceride cholesterol. Because calorie restriction (CR) modulates disease, it then was determined whether the effects CR mediated partially by modulation lipid metabolism. Compared ad libitum (AL)-fed 24-month-old (24 m) F344BN rats,...
Late referral of patients with chronic kidney disease (CKD) by primary care physicians (PCPs) is associated poor outcomes. We sought to assess factors influencing PCPs patterns in the general population and geriatric patients, compared their perceptions patterns.We retrospectively reviewed 268 Stage 3 CKD (early referral) 280 4 (appropriate seen renal clinic them randomly selected non-referred from office records. also surveyed 400 regional on for CKD.Non-referred were significantly (p <...
Background: Peritoneal dialysis (PD) is a more cost-effective therapy to treat kidney failure than in-center hemodialysis, but successful requires functioning PD catheter that causes minimal complications. In 2015, the North American Chapter of International Society for Dialysis established Catheter Registry improve practices and patient outcomes following insertion. Aims: The objective this study propose methodology defining insertion-related complications lead significant adverse events...
Background and objectives: Peritoneal dialysis (PD) depends on timely skilled placement of a PD catheter (PDC). Most PDCs are placed surgically, but little is known about the residency training surgeons in this procedure. Inadequate could limit surgical expertise PDCs, resulting high complication rates that discourage use. This study assessed PDC United States to explore issue. Design, setting, participants, & measurements: A survey was sent program directors 248 U.S. surgery programs...
Introduction: Kidney transplantation (KTX) is considered the treatment of choice for most individuals with end-stage kidney disease. The purpose this study was to assess employment status and social participation after successful KTX. Methods: This a retrospective cross-sectional study. Eligible participants were patients who received transplant ≥1 year ago previously on hemodialysis (HD) year. Two hundred participated in Results: A significant number (93.5%) reported they working prior HD...
Interest in nephrology has been declining recent years. Long work hours and a poor work/life balance may be partially responsible, also affect fellowship's educational mission. We surveyed program directors using web-based survey order to define current clinical practice patterns identify areas for improvement. Our explored fellowship demographics, fellows' workload, call structure, education. Program were asked estimate the average maximum number of patients on each their inpatient...
A 69-year-old man with type 2 diabetes, hypertension and stage 3 chronic kidney disease (CKD), hyperphosphataemia borderline hyperkalaemia presented to an office visit interested in changing his diet improve medical conditions. He adopted a strict whole-foods, plant-based diet, without calorie or portion restriction mandated exercise, rapidly reduced insulin requirements by >50%, subsequently saw improvements weight, blood pressure cholesterol. His estimated glomerular filtration rate (eGFR)...