Carmen Llena

ORCID: 0000-0002-3942-2820
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About
Contact & Profiles
Research Areas
  • Endodontics and Root Canal Treatments
  • Dental materials and restorations
  • Dental Radiography and Imaging
  • Irish and British Studies
  • Dental Erosion and Treatment
  • Oral microbiology and periodontitis research
  • Dental Health and Care Utilization
  • Dental Anxiety and Anesthesia Techniques
  • Bone Tissue Engineering Materials
  • Dental Trauma and Treatments
  • Dental Research and COVID-19
  • Dental Implant Techniques and Outcomes
  • Postcolonial and Cultural Literary Studies
  • Occupational health in dentistry
  • Bone and Dental Protein Studies
  • Contemporary Literature and Criticism
  • Health and Medical Education
  • Infective Endocarditis Diagnosis and Management
  • Poetry Analysis and Criticism
  • Salivary Gland Disorders and Functions
  • Oral and Maxillofacial Pathology
  • Aging, Health, and Disability
  • dental development and anomalies
  • Laser Applications in Dentistry and Medicine
  • Diaspora, migration, transnational identity

Universitat de València
2016-2025

Hospital General Universitario De Valencia
2023

Dalarna University
2014-2020

Hospital Lluis Alcanyis
2020

Hospital de Sant Pau
2013

Madrid Health Service
2011

Generalitat Valenciana
2004-2011

American Association of Endodontists
2010

Primary Health Care
2008

Universidad Cardenal Herrera CEU
2004-2007

Abstract Aims To investigate the cytotoxicity and bioactivity of several pulpotomy materials: Biodentine (Septodont, Saint‐Maur‐des‐Fosses, France) MTA (Angelus, Londrina, PR , Brazil), Theracal LC (Bisco Inc., Schamburg, IL USA ) IRM (Dentsply DeTrey GmbH, Konstanz, Germany), after contact with stem cells isolated from human exfoliated primary teeth ( SHED s). Methodology s were cultured in presence eluates various materials for 24, 48 72 h. Cell viability was determined by mitochondrial...

10.1111/iej.12751 article EN International Endodontic Journal 2017-02-07

Abstract Aim To evaluate the biological effects in vitro of MTA‐Angelus (MTA‐Ang; Angelus, Londrina, PR, Brazil), MTA Repair HP (MTA‐HP; Angelus) and NeoMTA Plus (NeoMTA‐P; Avalon Biomed Inc, Bradenton, FL, USA) on human dental pulp stem cells ( h DPSCs). Methodology Cell viability cell migration assays were performed using eluates each material. morphology attachment to different materials, hDPSCs directly seeded onto material surfaces analysed by immunocytofluorescence scanning electron...

10.1111/iej.12859 article EN International Endodontic Journal 2017-09-11

The aim of this study was to investigate the cytocompatibility and mineralization potential two premixed hydraulic endodontic sealers compared with an epoxy resin-based root canal sealer. cellular responses capacity were studied in human periodontal ligament stem cells (hPDLSCs) that exposed sealers, Bio-C Sealer (Angelus, Londrína, PR, Brazil), TotalFill BC (FKG Dentaire SA, La-Chaux-de-fonds, Switzerland) material, AH Plus (Dentsply De Trey, Konstanz, Germany). Non-exposed cultures served...

10.3390/ma12193087 article EN Materials 2019-09-22

The aim of this study was to assess the biological properties and mineralization potential new Theracal PT (Bisco Inc, Schaumburg, IL) compared with its predecessor LC Inc) hydraulic silicate-based cement Biodentine (Septodont, Saint-Maur-des-Fossés, France) on human dental pulp stem cells (hDPSCs) in vitro.Standardized sample discs were obtained for each material (n = 30) together 1:1, 1:2, 1:4 eluates. Previously characterized hDPSCs cultured different materials standardized conditions,...

10.1016/j.joen.2021.08.001 article EN cc-by-nc-nd Journal of Endodontics 2021-08-21

To assess the cytocompatibility and bioactive potential of new calcium silicate cement-based sealer AH Plus Bioceramic Sealer (AHPbcs) on human periodontal ligament stem cells (hPDLSCs) compared with epoxy resin-based (AHP) Endosequence BC (ESbcs).Standardized sample discs 1:1, 1:2 1:4 eluates tested materials were prepared. The following assays performed: surface element distribution via SEM-EDX, cell attachment morphology SEM, viability a MTT assay, migration/proliferation wound-healing...

10.1111/iej.13805 article EN cc-by International Endodontic Journal 2022-07-30

Abstract A few studies indicate that nitrate can reduce dysbiosis from a periodontitis point of view. However, these experiments were performed on samples healthy individuals, and it is unknown if will be effective in periodontal patients, where the presence nitrate-reducing bacteria clearly reduced. The aim this study was to test effect R. aeria (Ra9) subgingival biofilms patients with periodontitis. For this, plaque incubated 5 mM for 7 h ( n = 20) or 50 12 10), achieving ~50% reduction...

10.1038/s41522-023-00406-3 article EN cc-by npj Biofilms and Microbiomes 2023-06-17

To evaluate the biocompatibility of three calcium silicate-based endodontic sealers, Bioroot BC Sealer (Septodont, Saint-Maur-des-Fosses, France), Endoseal MTA (EndoSeal, Maruchi, Seoul, Korea) and Nano-ceramic (B&L Biotech, Fairfax, VA, USA) (NCS), on human periodontal ligament stem cells (hPDLSCs).Human were cultured in presence various sealer eluates for 24 h. Cell viability was determined using MTT assay. death changes phenotype induced by set evaluated through flow cytometry. Also, an...

10.1111/iej.12703 article EN International Endodontic Journal 2016-09-26

To evaluate the efficacy of augmented reality (AR) in gaining knowledge and skills amongst dental students design cavity preparations analyse their degree satisfaction.AR models were prepared for use with computers mobile devices. Forty-one divided into two groups (traditional teaching methods vs AR). Questionnaires designed to skills, administration a satisfaction questionnaire those using AR. The compliance standards was assessed. Mann-Whitney U-test used compare between groups, Wilcoxon...

10.1111/eje.12269 article EN European Journal Of Dental Education 2017-03-31

To evaluate in a laboratory setting the effects of Endosequence BC Sealer HiFlow (Brasseler USA, Savannah, GA, USA), novel calcium silicate-based sealer developed for use warm canal filling techniques, on human periodontal ligament stem cells (hPDLSCs).Eluates EndoSequence (BCHiF) (BCS) USA) and AH Plus (AHP) (Dentsply DeTrey GmbH, Konstanz, Germany) were placed contact with hPDLSCs. The characterization chemical elements root sealers was assessed using scanning electron microscopy...

10.1111/iej.13327 article EN International Endodontic Journal 2020-05-16

Biocompatibility is an essential property for any vital pulp material that may interact with the dental tissues. Accordingly, this study aimed to compare chemical composition and ultrastructural morphology of Biodentine (Septodont, Saint Maur-des-Fosses, France), ProRoot MTA (Dentsply Tulsa Dental Specialties, Johnson City, TN, USA), Bio-C Repair (Angelus, Londrina, PR, Brazil), as well their biological effects on human cells. Chemical element characterization materials was undertaken using...

10.3390/ma13092189 article EN Materials 2020-05-10

Abstract Objectives The aim of the present in vitro study is to determine cytocompatibility recently introduced NeoPutty contact with human dental pulp cells compared its precursor NeoMTA Plus and classic gold standard MTA Angelus. Materials methods Sample disks were obtained for each tested materials (5 mm diameter; 2 thickness; n = 30), along 1:1, 1:2, 1:4 material eluents. HDPCs extracted cultured (test groups) or unconditioned medium (control group), following biocompatibility assays...

10.1007/s00784-022-04682-9 article EN cc-by Clinical Oral Investigations 2022-09-02

Purpose: This study aimed to investigate the clinical anatomy of lower premolar roots in a Spanish population by using cone-beam computed tomography (CBCT), correlating findings with patient gender and tooth type.Materials Methods: Using 70 CBCT images, we evaluated 126 healthy, untreated, well-developed premolars.The number morphology root canals, foramina were assessed.Results for type compared chi-squared ANOVA tests. Results:The average length teeth was significantly higher men (p=...

10.5624/isd.2014.44.3.221 article EN cc-by-nc Imaging Science in Dentistry 2014-01-01

Streptococcus dentisani 7746, isolated from dental plaque of caries-free individuals, has been shown to have several beneficial effects in vitro which could contribute promote oral health, including an antimicrobial activity against pathogens by the production bacteriocins and a pH buffering capacity through ammonia production. Previous work that S. was able colonize cavity for 2-4 weeks after application. The aim present evaluate its clinical efficacy randomized, double-blind,...

10.3389/fcimb.2020.00465 article EN cc-by Frontiers in Cellular and Infection Microbiology 2020-08-31

Background/Objectives: Pulp stones (PSs) are calcified masses, with rounded or oval shapes, ranging from small particles to masses larger than the chamber and/or canals. There limited data regarding prevalence of pulp in Iberian population. Our aim was determine PSs, using CBCT, an population, and its association gender, age, tooth location (arch hemiarch), dental group, presence caries, restorations, alveolar bone loss, a history orthodontic treatment. Methods: In total, 300 CBCTs were...

10.3390/jcm14041373 article EN Journal of Clinical Medicine 2025-02-19
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