A5084906201- Health disparities and outcomes
- Cardiovascular Health and Risk Factors
- Obesity, Physical Activity, Diet
- Climate Change and Health Impacts
- Acute Ischemic Stroke Management
- Obstructive Sleep Apnea Research
- Nutritional Studies and Diet
- Heart Failure Treatment and Management
- Urban, Neighborhood, and Segregation Studies
- Blood Pressure and Hypertension Studies
- Physical Activity and Health
- Neuroscience of respiration and sleep
- Cardiac Health and Mental Health
- Birth, Development, and Health
- Consumer Attitudes and Food Labeling
- Cardiovascular Disease and Adiposity
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Effects of Exercise
- Employment and Welfare Studies
- Colorectal Cancer Surgical Treatments
- Dental Research and COVID-19
- Sepsis Diagnosis and Treatment
- Potassium and Related Disorders
- Health Policy Implementation Science
- Nutrition and Health in Aging
University of Alabama at Birmingham
2016-2025
Harvard University
2024
Chulalongkorn University
2024
Massachusetts General Hospital
2024
University of Alabama
2023
Cabrini Hospital
2020
Komfo Anokye Teaching Hospital
2017
University of Ibadan
2017
Alabama Department of Public Health
2016
Ultra-processed foods (UPFs) are linked to cardiometabolic diseases and neurologic outcomes, such as cognitive decline stroke. However, it is unclear whether food processing confers risk independent of dietary pattern information. We aimed (1) investigate associations between UPFs incident impairment stroke (2) compare these with other commonly recommended patterns in the REasons for Geographic Racial Differences Stroke study. This prospective, observational cohort study enrolled Black White...
Background and Purpose— The relative contributions of racial geographic factors to higher risk stroke in people African ancestry have not been unraveled. We compared type vascular among indigenous Africans (IA), Americans (AA), European (EA). Methods— SIREN (Stroke Investigative Research Educational Network) is a large multinational case–control study West Africa—the ancestral home 71% AA—whereas REGARDS (Reasons for Geographic Racial Differences Stroke) cohort including AA EA the United...
Recent studies have suggested that the natriuretic peptide system may be endogenously suppressed in black individuals who are free of prevalent cardiovascular disease. Whether levels contribute to racial disparities clinical outcomes is unknown.To examine differences N-terminal pro-B-type (NTproBNP) and their association with all-cause mortality cause-specific Reasons for Geographic Racial Differences Stroke (REGARDS) study.Baseline NTproBNP were measured a randomly selected sample 4415...
There have been mixed findings regarding the relationship between walkability and level of physical activity in adults.Participants from The REasons for Geographic Racial Differences Stroke (REGARDS) national cohort (N=7561) were used to examine association Walk Score measured via accelerometry. subsample included geographically diverse adults, who identified as black or white, over age 45. Linear regression was direct effects, well interaction, by sex, race.The majority participants lived a...
Introduction: Cerebral microbleeds (CMB) are subclinical markers of cerebral small vessel disease (CSVD) denoting increased risk stroke, cognitive impairment and dementia. The influence race region residence on the prevalence, burden brain location CMB is understudied. Aim: Determine impact geographic racial differences in prevalence among participants REGARDS cohort study. Methods: Among 30,239 followed since 2003-7 study, ratings was performed MRI from those with stroke or TIA. CMBs were...
Abstract Background Many older adults take at least one prescription medication with anticholinergic (ACH) activity, which can impact the central nervous system and lead to cognitive decline impairment especially in an aging population susceptible changes. We examined this relationship between ACH burden function middle‐aged adults. further determined if increased activity levels mitigated relationships cognition. Methods Data from The Reasons for Geographic Racial Differences Stroke project...
To examine the cross-sectional association between obstructive sleep apnea (OSA) risk and atrial fibrillation (AF) in REasons for Geographic And Racial Differences Stroke (REGARDS), a cohort of black white adults.Using REGARDS data from subjects recruited 2003-2007, we assessed 20,351 participants OSA status. High was determined if participant met at least two criteria Berlin Sleep Questionnaire (persistent snoring, frequent sleepiness, high blood pressure, or obesity). AF defined as...
ABSTRACT Purpose Sedentary behavior is associated with poor physical function in older adults, which can lead to accelerated skeletal muscle aging (sarcopenia) and premature mortality. We examined the independent joint effects of sedentary moderate vigorous intensity activity (MVPA) measures functioning. Methods studied 5408 participants REasons for Geographic Racial Differences Stroke study who wore a hip-mounted accelerometer over seven consecutive days (2009–2013) had self-reported...
Socioeconomic status (SES) is a well-established determinant of health. Disparities in stress are thought to partially account for SES-health disparities. We tested whether multiple indicators SES show similar associations with psychological and race, sex, geographic region moderate associations. Participants (n = 26,451) from well-characterized national cohort Black White US adults aged 45 years or older. Psychological was measured using the 4-item perceived scale. Income assessed as annual...
Epidemiological studies utilize residential histories to assess environmental exposure risk. The validity from using commercially-sourced within national longitudinal remains unclear. Our study assessed predictors of non-agreement between baseline addresses the LexisNexis database and participants in study, REasons for Geographic Racial Differences Stroke (REGARDS). Additionally, we differences stroke risk by neighborhood socioeconomic score (nSES) based on participant reported address...
Historically, double data entry (DDE) has been considered the criterion standard for minimizing errors. However, previous studies alternatives through limited lens of accuracy. This study supplies information regarding accuracy, operational efficiency, and cost DDE Optical Mark Recognition (OMR) processing Consumer Assessment Healthcare Providers Systems 5.0 survey.To assess we compared error rates OMR by dividing number surveys that were arbitrated total processed each method. To tallied...
A health disparity is a difference that adversely affects disadvantaged populations, and thus could plausibly be due to social factors. Biopsychosocial processes contribute disparities are not well-understood. Establishing whether candidate biomarkers similarly associated with biologically relevant psychosocial constructs across groups current gap in our understanding.
Abstract Background Postoperative mortality after colorectal cancer surgery varies across hospitals and countries. The aim of this study was to test the Association Coloproctologists Great Britain Ireland (ACPGBI) models as predictors 30-day in an Australian cohort. Methods Data from patients who underwent six between 1996 2015 (CRC data set) were reviewed ACPGBI models, 79 Bi-National Colorectal Cancer Audit 2007 2016 (BCCA analysed validate model performance. Recalibrated based on risk...
The study objective was to investigate the effects of childhood residential mobility on older adult physical and mental health. In REasons for Geographic Racial Differences in Stroke (REGARDS) Study, we used linear regression models if number moves during predicted health (SF-12 MCS, PCS), adjusting demographic covariates, socioeconomic status (SES), social support, adverse experiences (ACEs). We investigated interaction by age, race, SES, ACEs. People who moved more had poorer MCS scores, β...
Background: Poor cardiorespiratory fitness (CRF) is an independent predictor of cardiovascular disease (CVD). However, wide utilization CRF in CVD risk assessment limited due to its cost, and the need for exercise equipment skilled personnel. Estimated (e-CRF) based on readily available clinical self-reported data a promising alternative though role as incident atrial fibrillation (AF) remains unclear. Methods: This study included 10,126 participants (54.5% women, 35% African American, mean...
Abstract Falls can have life-altering consequences for older adults, including extended recovery periods and compromised independence. Higher household income may mitigate the risk of falls by providing financial resources mobility tools, remediation environmental hazards, needed supports, or it buffer impact an initial fall on subsequent through improved assistance care. Household has not had a consistently observed association with in adults; however, segmented exist such that associations...