A5103164872- Dementia and Cognitive Impairment Research
- Health disparities and outcomes
- Older Adults Driving Studies
- Aging and Gerontology Research
- Retirement, Disability, and Employment
- Employment and Welfare Studies
- Urban Transport and Accessibility
- Geriatric Care and Nursing Homes
- Acute Ischemic Stroke Management
- Frailty in Older Adults
- Health Systems, Economic Evaluations, Quality of Life
- Cognitive Abilities and Testing
- Blood Pressure and Hypertension Studies
- Health, Environment, Cognitive Aging
- Diabetes Management and Education
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Workplace Health and Well-being
- Musculoskeletal pain and rehabilitation
- Traumatic Brain Injury Research
- Cardiovascular Health and Risk Factors
- Botulinum Toxin and Related Neurological Disorders
- Neurological disorders and treatments
- Chronic Disease Management Strategies
- Urban, Neighborhood, and Segregation Studies
University of Alabama at Birmingham
2016-2025
Crowell & Moring (United States)
2012-2020
Indiana University Bloomington
2007
Medical College of Wisconsin
2006
University of Southern California
2000-2006
Milwaukee VA Medical Center
2006
Maudsley Hospital
1994
There are currently no proven treatments to reduce the risk of mild cognitive impairment and dementia.To evaluate effect intensive blood pressure control on dementia.Randomized clinical trial conducted at 102 sites in United States Puerto Rico among adults aged 50 years or older with hypertension but without diabetes history stroke. Randomization began November 8, 2010. The was stopped early for benefit its primary outcome (a composite cardiovascular events) all-cause mortality August 20,...
The effect of intensive blood pressure lowering on brain health remains uncertain.To evaluate the association treatment with cerebral white matter lesion and volumes.A substudy a multicenter randomized clinical trial hypertensive adults 50 years or older without history diabetes stroke at 27 sites in United States. Randomization began November 8, 2010. overall was stopped early because benefit for its primary outcome (a composite cardiovascular events) all-cause mortality August 20, 2015....
Background. With the number of people with dementia increasing, identifying potential protective factors has become more important. We explored association between physical exercise at midlife and subsequent risk among members HARMONY study.
This study examined whether participation in leisure activities during early and middle adulthood was associated with reduced risk of Alzheimer's disease. The sample consisted 107 same-sex twin pairs discordant for dementia whom information on self-reported more than 20 years prior to clinical evaluation. A factor analysis these yielded three activity factors: intellectual–cultural, self-improvement, domestic activity. Matched-pair analyses compared within the while controlling level...
The Useful Field of View test (UFOV) is increasingly used in clinical and rehabilitation settings. To date there have been no normative data for adjusted performance comparisons across demographically-similar, elderly peers. This study examined demographic cognitive influences on the UFOV a sample 2759 participants (65-94 years age). Performance was found to differ by age education. Regression analyses relative contributions age, education, mental status, vision, health performance. All...
Mild Cognitive Impairment (MCI) involves subtle functional losses that may include decrements in driving skills. We compared 46 participants with MCI to 59 cognitively normal controls on a evaluation conducted by rehabilitation specialist who was blinded participants' classification. Participants demonstrated significantly lower performance than ratings of global and discrete maneuvers, but these differences were not at the level frank impairments. Rather, simply less optimal, which lesser...
Background The study aimed to identify, classify and measure the relative frequency of events preceding violent incidents in psychiatric hospitals. Method Possible antecedents for 1000 three associated hospitals over 13 months were investigated with an ‘untoward incident database’. Results From eyewitness accounts, 921 (92%) could be related one 15 categories antecedent involving characteristics patient, or hospital regime, interactions other individuals. Overall, most common involved...
OBJECTIVES: To examine trajectories of change in everyday function for individuals with cognitive deficits suggestive mild impairment (MCI). DESIGN: Using data from the longitudinal, multisite Advanced Cognitive Training Independent and Vital Elderly Study allowed post hoc classification MCI status at baseline using psychometric definitions amnestic MCI, nonamnestic multidomain no MCI. SETTING: Six U.S. cities. PARTICIPANTS: Two thousand eight hundred thirty‐two volunteers (mean age 74; 26%...
Objectives To examine job control, demands, social support at work, and strain (ratio of demands to control) in relation risk any dementia, A lzheimer's disease ( AD ), vascular dementia VaD ). Design Cohort study. Setting The population‐based Study Dementia S wedish Twins. Participants Two hundred fifty‐seven people with (167 , 46 ) 9,849 without. Measurements diagnoses were based on telephone screening for cognitive impairment followed by in‐person clinical examination. An established...
We examined indicators of job strain in relation to level and change episodic memory the years leading up as well following retirement.Our analyses centre on 3779 individuals from nationally representative Health Retirement Study (baseline age 57.3 years) who reported gainful employment an occupation for 10+ prior retirement, were assessed performance over 20 (median 8 waves 16 years). used ratings Occupational Information Network (O*Net) score occupations control demands, measure (job...
Objective: To examine whether cognitive reserve (CR) attenuates the initial impact of traumatic brain injury (TBI) on performance (neural reserve) and results in faster recovery rates first year postinjury compensation), advantage CR differs basis severity TBI. Setting: Inpatient/outpatient clinics at an academic medical center. Participants: Adults with mild TBI (mTBI; n = 28), complicated (cmTBI; 24), moderate to severe (msevTBI; 57), demographically matched controls ( 66). Design:...
How to Obtain Contact Hours by Reading This Article Instructions 1.2 contact hours will be awarded Villanova University College of Nursing upon successful completion this activity. A hour is a unit measurement that denotes 60 minutes an organized learning learner-based does not require submission your answers the quiz. certificate once you register, pay registration fee, and complete evaluation form online at http://goo.gl/gMfXaf . To obtain must: 1. Read article, “Associations Social...
The authors examined the relationship between personality and cognitive impairment in 4,039 members of Swedish Twin Registry. Neuroticism extraversion scores were collected 1973 at midlife, was assessed same group 25 years later. Data analyzed with case-control co-twin control designs. Greater neuroticism associated higher risk results from case-control, but not co-twin, analyses. Compared both introversion, moderate lower designs, as combination high low extraversion. Findings are discussed...
We used data from SWEOLD, a Swedish nationally representative study of individuals aged 77 years or older, to examine midlife indicators job strain in relation cognitive performance and impairment. In all, 827 participants completed an abridged 11-point version the Mini-Mental State Examination in-person 1992 and/or 2002 had self-reported occupation-based scores for control demands collected 1968. Seventeen percent scored below cutoff Controlling age, sex, education, self-rated health, year...
To determine whether incidence of impaired cognitive screening status is higher in the southern Stroke Belt region United States than remaining States.A national cohort adults age ≥45 years was recruited by Reasons for Geographic and Racial Differences (REGARDS) study from 2003 to 2007. Participants' global assessed annually telephone with Six-Item Screener (SIS) every 2 fluency recall tasks. Participants who reported no stroke history were cognitively intact at enrollment (SIS >4 6)...
Positive associations between education and late-life cognition have been widely reported. This study examines whether occupational complexity mediates the relationship cognition, magnitude of mediation differs by race, gender, or level.Data were from a population-based cohort non-Hispanic Blacks Whites aged ≥45 years (n = 7,357). Education was categorized as less than high school, some college, college higher. Using linear regression, we estimated direct effect each successive increase in...
Abstract Background Dementia shows sex difference in its epidemiology. Childbirth, a distinctive experience of women, is associated with the risk for various diseases. However, association dementia women has rarely been studied. Methods We harmonized and pooled baseline data from 11 population-based cohorts countries over 3 continents, including 14,792 aged 60 years or older. investigated between parity using logistic regression models that adjusted age, educational level, hypertension,...