A5102950115- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Veterinary medicine and infectious diseases
- Clostridium difficile and Clostridium perfringens research
- Catalytic Processes in Materials Science
- Pain Mechanisms and Treatments
- Parasite Biology and Host Interactions
- Anesthesia and Pain Management
- Rheumatoid Arthritis Research and Therapies
- Microscopic Colitis
- Parasites and Host Interactions
- Healthcare and Venom Research
- Metal-Organic Frameworks: Synthesis and Applications
- Anesthesia and Sedative Agents
- Immune Response and Inflammation
- Catalysis and Hydrodesulfurization Studies
- Intensive Care Unit Cognitive Disorders
- Acupuncture Treatment Research Studies
- Helminth infection and control
- Nausea and vomiting management
- Phosphorus and nutrient management
- Salivary Gland Disorders and Functions
Northeast Petroleum University
2025
Zhejiang Hospital
2024
Peking University
2012-2023
Peking University Third Hospital
2010-2023
Zhangzhou Normal University
2023
Guangdong Academy of Medical Sciences
2020-2022
Guangdong Provincial People's Hospital
2020-2022
Shanghai Jiao Tong University
2016-2021
Renji Hospital
2021
Linyi City Chinese Medicine Hospital
2021
Abstract Background With markedly increased antibiotic resistance and unsatisfactory efficacies of common empiric eradication regimens in the mainland China, tailored therapy may be best choice to achieve good efficacy. This study compared rates, safety, compliance those triple plus bismuth concomitant naïve patients with Helicobacter pylori infection. Materials Methods Between September 2013 April 2014, 1050 H. infection at three tertiary hospitals were randomly assigned 10‐day treatment...
Favorable outcomes in treating H pylori infection using "dual therapy (proton pump inhibitor and amoxicillin four times daily)" have attracted widespread attention. However, there are few reports, the study results lack agreement. This aimed to compare eradication rate, safety, compliance of naïve-treatment patients with on therapy" those "triple plus bismuth (TPB) therapy."This is a non-inferior randomized controlled trial conducted 760 infection. The participants were randomly assigned two...
Abstract Background The impact of probiotics on non‐ Helicobacter pylori gastric microbiota and its role in microbial restoration after eradication were relatively unknown. We aimed to explore the effect H. probiotic intervention young adults. Methods Fifty‐six ‐negative 95 ‐positive subjects aged 19–30 included this study. ‐infected individuals randomly assigned quadruple therapy, supplemented or monotherapy group. Gastric mucosa juice samples collected before 2 months treatment for 16SrRNA...
Helicobacter pylori (H. pylori) eradication has been widely used. The recurrence rate of H. after and its related factors are gaining more attention. Our study aimed to determine the infection successful eradication, analyze influential factors.We prospectively studied 1050 patients with upper gastrointestinal symptoms who were diagnosed as by gastroscopy underwent therapies from April 2013 January 2014. C-urea breath test (UBT) or Warthin-Starry (WS) staining was done at 8 12 weeks therapy....
The capture of CO2 with chemical looping combustion (CLC) offers a novel approach to significantly reduce carbon emissions while simultaneously utilizing captured as valuable resource by leveraging its inherent separation capability. in CLC technology achieves low-cost through the utilization highly efficient oxygen carriers (OC), enabling coupling subsequent hydrogenation reactions for high-value-added production. This review comprehensively summarizes principle technology, current status...
Background Helicobacter pylori (Hp) is a common and potentially curable cause of gastric mucosa lesion. This study investigated the relationship Hp infection with histological changes in cancer Hp-positive patients compared Hp-eradication followed up for ten years. Methods From an initial group 1 006 adults, 552 subjects were randomly assigned to treatment (T; n =276) or placebo (P; =276). In randomized, double-blind, placebo-controlled, parallel trial, T received oral doses omeprazole,...
To assess the performance of self-assessment gastroesophageal reflux disease questionnaire (GerdQ), 24-h impedance monitoring, proton pump inhibitor (PPI) test and intercellular space esophageal mucosal epithelial cells in diagnosis (GERD).Patients with symptoms suspected GERD were administered GerdQ underwent endoscopy (measurement biopsy specimen sampling at 2 cm above Z-line) pH together a 2-week experimental treatment esomeprazole.A total 636 patients included for final analysis,...
Abstract Background Hybrid therapy has recently attracted widespread attention. However, many issues require further exploration. For example, research in regions with high antibiotic resistance rates is limited, and the correlation between eradication efficacy remains unclear. The aim of this study was to determine efficacy, compliance, safety, risk factors hybrid as first‐line regimen a region rates. Materials Methods This prospective conducted tertiary hospital January 2014 June 2015. A...
Background: It has not been fully confirmed whether the detection of Helicobacter pylori resistance gene mutation can replace antibiotic drug sensitivity test to guide clinical individualized treatment. Therefore, we have studied this aspect and discussed application value test. Materials Methods: The biopsy specimen gastric mucosa from patients examined by endoscopy positive for rapid urease were collected continuously histopathological analysis, H. culture, (E-test test), (high-throughput...
Objective Recurrence of Helicobacter pylori ( H. ) infection weakens the protective effect and long‐term prognosis eradication. With widespread therapies, decreasing prevalence improvement in living conditions, recurrence may present with new features. We conducted this prospective, large‐scale, multicenter follow‐up study to determine rate its affecting factors. Methods A total 827 patients receiving successful eradication our previous randomized controlled trial were enrolled. 13 C‐urea...
In this paper, we report the design, synthesis and biological evaluation of a novel S-allyl-l-cysteine (SAC) gallic acid conjugate S-(4-fluorobenzyl)-N-(3,4,5-trimethoxybenzoyl)-l-cysteinate (MTC). We evaluate effects on ischemia-reperfusion-induced PC12 cells, primary neurons in neonatal rats, cerebral ischemic neuronal damage results showed that MTC increased SOD, CAT, GPx activity decreased LDH release. PI3K p-AKT protein levels were significantly by activating PI3K/AKT pathway....
Background: Helicobacter pylori (H. pylori) frequently colonizes the stomach. Gastroesophageal reflux disease (GERD) is a common and costly disease. But relationship of H. GERD still unclear. This study aimed to explore effect its eradication on esophagitis therapy. Methods: Patients diagnosed with by endoscopy were enrolled; based rapid urease test Warth–Starry stain, they divided into positive negative groups. patients randomly given treatment for 10 days, then esomeprazole 20 mg bid 46...
Background Gastroesophageal reflux disease (GERD) is a common disorder. Dilation of intercellular spaces esophageal epithelium has been revealed at transmission electron microscopy both in the rabbit acid-perfused esophagus and biopsies from GERD patients. This study aimed to observe changes squamous lower patients with erosive esophagitis (EE) before after omeprazole treatment. Methods Outpatients having symptoms for more than 3 months volunteers were collected. All them underwent...
The study aims to determine whether light microscopy can be used accurately measure the diameters of intercellular spaces between squamous epithelial cells in lower esophagus, and changes this outcome as a diagnostic marker for gastroesophageal reflux disease (GERD). has two parts. Part 1 involves 42 asymptomatic controls 119 patients with typical symptoms GERD, including 58 erosive esophagitis (EE), 61 nonerosive (NERD). All biopsies were taken from esophagus. samples observed using an...
The aim of this paper is to investigate the diagnostic value histopathologic score and dilated intercellular space (DIS) in patients with gastroesophageal reflux disease (GERD) functional heartburn (FH). Participants GERD symptoms including esophagitis, non-erosive (NERD), Barrett's esophagus (BE), (FH), along a control group atypical GERD-like symptom (Sym-C), asymptomatic healthy volunteers (H-C) were administered questionnaire, subjected endoscopy biopsies, as well 24-hour pH-impedance...