A5054402380- Catalytic Processes in Materials Science
- Catalysis and Oxidation Reactions
- Diamond and Carbon-based Materials Research
- dental development and anomalies
- Catalysis and Hydrodesulfurization Studies
- Orthodontics and Dentofacial Orthopedics
- Bone Metabolism and Diseases
- Force Microscopy Techniques and Applications
- CAR-T cell therapy research
- High-pressure geophysics and materials
- Immunotherapy and Immune Responses
- interferon and immune responses
- Advanced Fiber Laser Technologies
- Immune Cell Function and Interaction
- Extraction and Separation Processes
- Cytokine Signaling Pathways and Interactions
- Atomic and Subatomic Physics Research
- Radioactive element chemistry and processing
- NF-κB Signaling Pathways
- Ferroptosis and cancer prognosis
- Bauxite Residue and Utilization
- Cancer-related molecular mechanisms research
- Electrocatalysts for Energy Conversion
- Immune cells in cancer
- Dental materials and restorations
University of Toyama
2025
Southern Medical University
2014-2024
Zhejiang Normal University
2021-2023
Chengdu Jincheng College
2023
Chengdu Medical College
2023
Dalian University of Technology
2023
Shaanxi Polytechnic Institute
2023
Guangdong University of Petrochemical Technology
2023
First Hospital of Jilin University
2023
Jilin University
2023
Periodontitis is admittedly a microbe-driven intractable infectious disease, in which Porphyromonas gingivalis (Pg) plays keystone role. Pg can selectively impair the antimicrobial responses of periodontal resident macrophages including their phagocytic and bactericidal activity without interfering proinflammatory activity, leads to microflora disturbance, destructive inflammation alveolar bone loss eventually. Here, an injectable ROS-sensitive hydrogel developed for releasing active...
Energy transfer (ET) is an important route to manage the population density of excited states, giving rise spectrally tunable emission that valuable for multicolor imaging and biological tracking. In this paper, a case study GdF3 nanoparticles (NPs) codoped with Yb3+ Er3+ was used experimentally theoretically investigate ET mechanisms under near-infrared violet excitation. Red-to-green ratio (RGR) as primary evaluating protocol, power-dependent luminescence 4I13/2 behavior are identify...
Abstract The relationship of obesity and osteoporosis has been widely studied over the past years. However, implications for bone health remain controversial, underlying molecular mechanism is not yet fully understood. This study demonstrated that high‐fat diet‐induced leads to significantly decreased volume/tissue volume (BV/TV), trabecular number (Tb.N), cortical thickness (Ct.Th) male rat femur after mechanical loading effects body weight were controlled. HFD‐induced obese rats exhibited...
Diamond nitrogen-vacancy (NV) center-based magnetometry provides a unique opportunity for quantum bio-sensing. However, NV centers are not sensitive to parameters such as temperature and pressure, immune many biochemical pH non-magnetic biomolecules. Here, we propose scheme that can potentially enable the measurement of various using diamond sensing, by employing stimulus-responsive hydrogels spacing transducer in-between nanodiamond (ND, with centers) magnetic nanoparticles (MNPs). The...
Osteoarthritis (OA) is a degenerative disease characterised by articular cartilage destruction, and its complex aetiology contributes to suboptimal clinical treatment outcomes. A close association exists between glucose metabolism dysregulation OA pathogenesis. Owing the unique environment of low oxygen concentrations, chondrocytes rely heavily on their glycolytic capacity, exhibiting distinct spatiotemporal differences. However, under pathological stimulation, undergo excessive activity...
In recent years, the immune-potentiating effects of some widely used chemotherapeutic agents have been increasingly appreciated. This provides a rationale for combining conventional chemotherapy with immunotherapy strategies to achieve durable therapeutic benefits. Previous studies implicated immunomodulatory melphalan, an alkylating agent commonly treat multiple myeloma, but underlying mechanisms remain obscure. present study, we investigated impact melphalan on endogenous immune cells as...
Abstract Nitrogen-vacancy (NV) centers in diamond are promising quantum sensors because of their long spin coherence time under ambient conditions. However, resonances relatively insensitive to non-magnetic parameters such as temperature. A magnetic-nanoparticle-nanodiamond hybrid thermometer, where the temperature change is converted magnetic field variation near Curie temperature, were demonstrated have enhanced sensitivity ($11{\rm{\,\,mK\,\,H}}{{\rm{z}}^{ - 1/2}}$) (Wang N, Liu G-Q and...
Pt/CeO2 and Pt/Nb2O5 catalysts were employed to catalyze CO propane oxidation. It was found that the catalyst more active than for oxidation, while it less in The different behaviors closely related nature of support, which affected properties Pt species as well reaction pathways. For took place at Pt–CeO2 interface catalyst. facile activation oxygen on CeO2 with abundant vacancies accounted its high activity, competitive adsorption O2 surface atoms led a strong inhibiting role reactivity,...
Correlated translation-orientation tracking of single particles can provide important information for understanding the dynamics live systems and their interaction with probes. However, full six-dimensional (6D) motion has yet to be achieved. Here, we developed synchronized 3D translation rotation diamond based on nitrogen-vacancy center sensing. We first performed 6D attached a giant plasma membrane vesicle demonstrate method. Quantitative analysis particles' allowed elimination geometric...
Abstract The immune and skeletal systems share common mechanisms, the crosstalk between two has been termed osteoimmunology. Osteoimmunology mainly focuses on diseases bone including loss diseases, imbalances in osteoimmune regulation affect homeostasis osteoclasts osteoblasts. mediator interleukin‐20 (IL‐20), a member of IL‐10 family, enhances inflammation, chemotaxis angiogenesis related to loss. However, it is unclear how IL‐20 regulates balance osteoclastogenesis osteoblastogenesis;...
Shallow nitrogen-vacancy (NV) centers in diamond are promising for nanomagnetometry, they can be placed proximate to targets. To study the intrinsic magnetic properties, zero-field magnetometry is desirable. However, shallow NV under zero field, strain near surfaces would cause level anticrossing between spin states, leading clock transitions whose frequencies insensitive signals. Furthermore, charge noises from induce extra decoherence and hence reduce sensitivity. Here, we demonstrate that...
The characterization and leaching mechanism of REEs from phosphogypsum (PG) in HCl was studied in-depth. contained the PG were 208 ppm, which Y, La, Ce, Nd four most abundant elements. modes occurrence rare earth elements (REEs) quantified using sequential chemical extraction (SCE) method. Among five REE species, metal oxide form accounted for largest proportion, followed by residual, organic matter, ion-exchangeable fractions, bound to carbonates least. From comparison distributions calcium...
Abstract Increased availability of homeostatic cytokines is considered a major mechanism by which lymphodepletion enhances the efficacy adoptive T cell therapy (ACT). IL-7 one such cytokine capable augmenting function tumor-reactive CD8+ cells. However, whether host-derived plays role in driving proper CD4+ cells an ACT setting remains unclear. Here we report that lymphodepleting chemotherapy cyclophosphamide (CTX) does not lead to increased endogenous mice. Despite paucity immune milieu,...
The functional status of CD4+ T cells is a critical determinant antitumor immunity. Polyfunctional possess the ability to concomitantly produce multiple Th1-type cytokines, exhibiting attribute desirable for cancer immunotherapy. However, mechanisms by which these are induced neither defined nor it clear if can be used therapeutically treat cancer. Here, we report that exposed exogenous IL-7 during antigenic stimulation acquire polyfunctional phenotype, characterized their simultaneously...