A5015348873- Temporomandibular Joint Disorders
- Periodontal Regeneration and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Orthodontics and Dentofacial Orthopedics
- Bone Metabolism and Diseases
- dental development and anomalies
- Facial Nerve Paralysis Treatment and Research
- Cardiac Structural Anomalies and Repair
- Cytokine Signaling Pathways and Interactions
- Ferroptosis and cancer prognosis
- Proteoglycans and glycosaminoglycans research
- Facial Rejuvenation and Surgery Techniques
- Surface Modification and Superhydrophobicity
- Credit Risk and Financial Regulations
- Antimicrobial Peptides and Activities
- Botulinum Toxin and Related Neurological Disorders
- Photonic and Optical Devices
- Osteoarthritis Treatment and Mechanisms
- Extracellular vesicles in disease
- Peptidase Inhibition and Analysis
- Bone and Dental Protein Studies
- Cancer-related molecular mechanisms research
- Analytical Chemistry and Sensors
- Oral microbiology and periodontitis research
- Nonlinear Optical Materials Research
Stomatology Hospital
2022-2024
Sun Yat-sen University
2022-2024
China Three Gorges University
2023
Sichuan University
2019-2022
State Key Laboratory of Oral Diseases
2019-2022
The applications of hydrogels have expanded significantly due to their versatile, highly tunable properties and breakthroughs in biomaterial technologies. In this review, we cover the major achievements potential therapeutic applications, focusing primarily on two areas: emerging cell-based therapies promising non-cell modalities. Within context cell therapy, discuss capacity overcome existing translational challenges faced by mainstream therapy paradigms, provide a detailed discussion...
Periodontitis is admittedly a microbe-driven intractable infectious disease, in which Porphyromonas gingivalis (Pg) plays keystone role. Pg can selectively impair the antimicrobial responses of periodontal resident macrophages including their phagocytic and bactericidal activity without interfering proinflammatory activity, leads to microflora disturbance, destructive inflammation alveolar bone loss eventually. Here, an injectable ROS-sensitive hydrogel developed for releasing active...
Financial stability plays an important role in the economic and social development of any economy. This study selects daily frequency data 20 indicators from money market, stock bond market foreign exchange China as research foundation. Firstly, construct Index China's Stability (ICFS) by Dynamic Weighting Method based on time-varying correlation coefficient, divide ICFS into three categorical variables (high medium low) Markov Regime Switching Model, results demonstrate that high risk...
Abstract The relationship of obesity and osteoporosis has been widely studied over the past years. However, implications for bone health remain controversial, underlying molecular mechanism is not yet fully understood. This study demonstrated that high‐fat diet‐induced leads to significantly decreased volume/tissue volume (BV/TV), trabecular number (Tb.N), cortical thickness (Ct.Th) male rat femur after mechanical loading effects body weight were controlled. HFD‐induced obese rats exhibited...
Strontium ranelate (SR) is a pharmaceutical agent used for the prevention and treatment of osteoporosis fragility fracture. However, little attention has been paid to effect SR on alveolar bone remodeling during orthodontic tooth movement its underlying mechanism. Here, we investigated influence resorption in Sprague-Dawley rats relationship between nuclear factor-kappa B (NF-κB) pathway, autophagy, osteoclastogenesis after administration vitro vivo. In this study, it was found that reduced...
Osteosarcoma, a predominant malignant tumor among adolescents, exhibits high mortality and suboptimal immunotherapy efficacy due to collagen-dense extracellular matrix (ECM) that hinders cytotoxic T lymphocyte (CTL) infiltration. Herein, we developed mesoporous polydopamine (MPDA) nanoparticles encapsulating bromelain the immune adjuvant R848 (M@B/R), aimed at enhancing photothermal immunotherapy. These efficiently accumulate site following injection. Upon near-infrared (NIR) light...
Mechanical force-mediated bone remodeling is crucial for various physiological and pathological processes involving multiple factors, including stem cells the immune response. However, it remains unclear how respond to mechanical stimuli modulate microenvironment subsequent remodeling. Here, we found that force induced increased expression of CD109 on periodontal ligament (PDLSCs) in vitro tissues from force-induced tooth movement rat model vivo, accompanied by activated alveolar Under...
Rheumatoid arthritis (RA) is a chronic immune disease involving the small joints, which often causes irreversible damage. In recent years, elevated interleukin 20 (IL-20) has been observed in synovial fluid, while IL-20 receptor overexpression cells. pleiotropic cytokine that participates various diseases. Further understanding of relationship between and RA can help to identify potential clinical treatment for RA. This study demonstrated regulate osteoclast differentiation function...
Clear aligners have been widely used to treat malocclusions from crowding, extraction cases orthodontic-orthognathic cases, and practitioners are exploring the border of it. For first time, clear were early intervene anterior cross-bite facial asymmetry.This case report described a four-year-old child presented with asymmetry associated functional mandibular shift, who had undergone failed treatment conventional appliances. The total time was 18 weeks, stable outcome obtained.The increasing...
Temporomandibular disorder (TMD) remained a huge clinical challenge, with high prevalence but limited, unstable, and only palliative therapeutic methods available. As one of the most vulnerable sites implicated in TMD, temporomandibular joint disc (TMJD) displayed complicated microstructure, region-specific fibrocartilaginous distribution, poor regenerative property, which all further hindered its functional regeneration. To address problem, versatile relatively simple electrospinning (ELS)...
Recently, organic photodetectors (OPDs) have occupied a crucial position in the photoelectric industry due to their low cost and convenient production. For its potential applications near-infrared (NIR) wavelengths, NIR-OPDs with high responsivity detectivity attracted lot of research interest. In this manuscript, we designed synthesized new n-type semiconductor, TPBT-OR, by introducing alkoxythiophene into Y5. TPBT-OR exhibits small optical bandgap 1.20 eV red-shifted absorption peaks 882...