Shan Xiao

ORCID: 0000-0002-2872-9835
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About
Contact & Profiles
Research Areas
  • Meat and Animal Product Quality
  • Ovarian function and disorders
  • Protein Hydrolysis and Bioactive Peptides
  • Probiotics and Fermented Foods
  • Reproductive Biology and Fertility
  • Assisted Reproductive Technology and Twin Pregnancy
  • Animal Nutrition and Physiology
  • Multiple Sclerosis Research Studies
  • Food Quality and Safety Studies
  • Fatty Acid Research and Health
  • Phytochemicals and Antioxidant Activities
  • Aquatic life and conservation
  • Echinoderm biology and ecology
  • Gut microbiota and health
  • Biochemical effects in animals
  • GABA and Rice Research
  • Nanoplatforms for cancer theranostics
  • Reproductive System and Pregnancy
  • Biochemical Analysis and Sensing Techniques
  • Aquaculture disease management and microbiota
  • Microbial Metabolic Engineering and Bioproduction
  • Polyomavirus and related diseases
  • Bee Products Chemical Analysis
  • Ectopic Pregnancy Diagnosis and Management
  • Proteins in Food Systems

Hunan Provincial Center for Disease Control and Prevention
2012-2025

Takeda (United States)
2022-2024

Dongguan University of Technology
2019-2024

Innovation Team (China)
2023-2024

Shenzhen Zhongshan Urological Hospital
2015-2024

Southern Medical University
2024

Qilu Hospital of Shandong University
2017-2024

Dalian Polytechnic University
2012-2024

Shenzhen Second People's Hospital
2021-2024

Guangxi Academy of Fishery Sciences
2024

John Foley Gilles Defer Lana Zhovtis Ryerson Jeffrey A. Cohen Douglas L. Arnold and 95 more Helmut Butzkueven Gary Cutter Gavin Giovannoni Joep Killestein Heinz Wiendl Karen Smirnakis Shan Xiao George Kong Robert Kuhelj Nolan Campbell Anneke van der Walt Chris Dwyer Katherine Buzzard Judith Spies Nevin John Vincent Van Pesch Barbara Willekens Gaetano Perrotta E Bartholomé François Grand’Maison François Jacques Paul S Giacomini Reza Vosoughi Jean-Marc Girard de Sèze Christine Lebrun‐Frénay Aurélie Ruet David Laplaud Gerd Reifschneider Bert Wagner Sebastian Rauer Refik Pul Maria Seipelt Achim Berthele Luisa Klotz Boris-Alexander Kallmann Friedemann Paul Anat Achiron Giacomo Lus Diego Centonze Francesco Patti Luigi Maria Grimaldi Raymond Hupperts S. T. F. M. Frequin Jiske Fermont Sara Eichau Madueño Ana Alonso Lucienne Costa‐Frossard José Meca-Lallana Luís Brieva Owen Pearson David Rog Nikos Evangelou Azza Ismail Ellen Lathi Edward Fox Thomas Leist Jacob A. Sloane Gregory F. Wu Bhupendra Khatri Brian Steingo Ben Thrower Mark Gudesblatt Jonathan Calkwood Daniel S. Bandari John Scagnelli Christopher LaGanke Derrick Robertson Lucas Kipp Martin Belkin Stanley Cohan Lawrence Goldstick Ardith Courtney Wendy Vargas Andrew Sylvester Jayshri Srinivasan Meena Kannan Maryann Picone Jeffrey English Salvatore Napoli Roumen Balabanov Islam Zaydan Jacqueline Nicholas Jeffrey Kaplan Fred Lublin Emily Riser Tamara Miller Enrique Álvarez Sibyl Wray Jeffrey B. Gross Siddharama Pawate Carrie M. Hersh Lucas McCarthy Heidi Crayton Jennifer Graves

10.1016/s1474-4422(22)00143-0 article EN The Lancet Neurology 2022-04-25

A total of 120 4-week-old broiler chickens were allotted to 12 pens and fed one three diets including control, oxidized diet (5% oil), or antioxidant-added (500 IU vitamin E) for 2 weeks. Blood samples collected at the end feeding trial, breast muscles sampled immediately after slaughter. Breast meats also 24 h slaughter used meat quality measurements. Oxidative stress in blood, lipid protein oxidation, sarcoplasmic reticulum Ca2+-ATPase (SERCA) activity muscle determined. The increased...

10.1021/jf102918z article EN Journal of Agricultural and Food Chemistry 2010-12-30

This study was designed to evaluate the effects of dietary treatment, packaging, and irradiation singly or in combination on oxidative stability broiler chicken thigh meat. A total 120 four-week-old chickens were divided into 12 pens (10 birds/pen), 4 broilers randomly assigned a control oxidized diet (5% oil) an antioxidant-added [500 IU vitamin E + 200 mg/kg butylated hydroxyanisole (BHA)] fed for 2 wk. After slaughter, meats separated, ground, packaged either oxygen-permeable...

10.3382/ps.2010-01244 article EN cc-by-nc-nd Poultry Science 2011-05-19

Abstract Temozolomide (TMZ)-resistance hampers the therapeutic efficacy of this drug for glioblastoma (GBM) treatment in clinic, and emerging evidences suggested that exosomes from GBM-derived stem cells (GSCs) contributed to process, but detailed mechanisms are still largely unknown. In present study, we reported GSCs derived programmed death-ligand 1 (PD-L1) containing activated AMPK/ULK1 pathway mediated protective autophagy enhanced TMZ-resistance GBM vitro vivo. Specifically, noticed...

10.1186/s13578-021-00575-8 article EN cc-by Cell & Bioscience 2021-03-31

Thus far, little is known about whether jackfruit flake, a byproduct of jackfruit, can be used as fermentation substrate to obtain value-added products through microbial fermentation. Here, flake puree was fermented by three different ways: spontaneous (JF), inoculated with LAB (JFL), co-fermentation and yeast (JFC). In contrast JF, the total polyphenol flavonoid content syndrome-associated enzyme inhibition are significantly increased in JFC at end Electronic tongue analysis revealed that...

10.1016/j.fochx.2024.101164 article EN cc-by-nc-nd Food Chemistry X 2024-01-30

In this study, a new fermented food was developed using pineapple by-products and whey protein (2.6%) as raw materials through the co-fermentation of autochthonous lactic acid bacteria yeast. To better understand fermentation mechanism impact microorganisms on entire system, we tracked changes in carbohydrate amino profiles, organoleptic quality microbial community during process. Compared with unfermented samples, dietary fiber free acids increased significantly proceeded. The samples were...

10.1016/j.fochx.2024.101254 article EN cc-by-nc-nd Food Chemistry X 2024-02-28

Astaxanthin is an important antioxidant with many biological activities such as anti-tumor, anti-obesity, cardioprotective, and immuno-modulatory activities. Most of these are derived from (3S,3'S)-astaxanthin, while the (3R,3'R)-astaxanthin rarely reported. The purpose this study was to investigate effect on lipid metabolism gut microbiota in mice fed a high-fat diet. In work, 40 male C57BL/6 were divided into 8 groups diet supplemented or not Xanthophyllomyces dendrorhous for weeks. weight...

10.3390/md17060337 article EN cc-by Marine Drugs 2019-06-05

Background: The risk of adverse pregnancy outcomes is increased by having a polycystic ovary syndrome (PCOS) diagnosis. However, the confounders in previous studies preclude firm conclusions, and further are warranted. Objectives: To investigate whether PCOS affects complications infertile women undergoing their first vitro fertilization (IVF) treatment, taking into account important confounders. Methods: We performed retrospective cohort study 7678 women, including 666 with 7012 controls...

10.3389/fendo.2020.575337 article EN cc-by Frontiers in Endocrinology 2020-09-25

The inhibition of autophagy is a feasible clinical strategy in tumor therapy. Traditional inhibitors are limited therapy due to nonspecific biodistribution, systemic toxicity and antitumor effect. Herein, the inhibitor hydroxychloroquine (HCQ)-loaded nanodroplets (NDs) synthesized overcome these drawbacks. HCQ-NDs endowed with endogenous pH- exogenous ultrasound-responsive drug release contrast enhanced ultrasound imaging performance. combined application ultrasound-targeted microbubble...

10.1016/j.jconrel.2022.01.009 article EN cc-by-nc-nd Journal of Controlled Release 2022-01-24

Value-added utilization of pineapple waste is very import for the food industry and environmental protection. In this study, whey protein (2.6%, w/w) was added to in order make up deficiency raw material give final products better flavor characteristics. Autochthonous Lactococcus lactis LA5 Hanseniaspora opuntiae SA2 were used co-inoculation by-products; during fermentation, metabolite profiling microbial community dynamics investigated. Results showed that contents organic acids, total...

10.3390/fermentation9020079 article EN cc-by Fermentation 2023-01-17

Multiple drug resistance (MDR) exists in divergent cancers including triple negative breast cancer (TNBC) and partly results the to many first-line anti-cancer agents, bringing a big challenge TNBC management. To develop novel therapeutics, our study, hyaluronic acid (HA)–carboxymethyl chitosan (CMC) conjugate linked via disulfide-bond (HA-SS-CMC, HSC) was synthesized fabricate nanodroplets (NDs). The NDs encapsulating doxorubicin (DOX) perfluorohexane (DOX-HSC-NDs) were prepared...

10.1021/acsami.2c20478 article EN ACS Applied Materials & Interfaces 2023-02-09

Casein-derived peptides are recognized as promising candidates for improving zinc bioavailability through the form of a peptide-zinc chelate. In present work, novel 11-residue peptide TEDELQDKIHP identified from casein hydrolysate in our previous study was synthesized to investigate chelation characteristics. Meanwhile, digestion stability and transepithelial transport TEDELQDKIHP-Zn were also investigated. The obtained results indicated that carboxyl groups (from Asp Glu), amino Lys His),...

10.1021/acs.jafc.3c00001 article EN Journal of Agricultural and Food Chemistry 2023-05-02

Compound K (CK; 20-O-D-glucopyranosyl-20(S)-protopanaxadiol), a major metabolite of ginsenoside, has been shown to possess several biological activities such as potent antitumor properties. However, the effect CK on apoptosis bladder cancer cells and its underlying mechanisms remain poorly understood. Therefore, we examined T 24 cells. Cell counts showed that treatment T24 with decreased cell number in dose- time-dependent manner. Flow cytometric analysis revealed could significantly induce...

10.1089/cbr.2012.1468 article EN Cancer Biotherapy and Radiopharmaceuticals 2013-07-30
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