A5058879862- Multiple Sclerosis Research Studies
- Polyomavirus and related diseases
- Amyotrophic Lateral Sclerosis Research
- Cerebral Venous Sinus Thrombosis
- Stroke Rehabilitation and Recovery
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neurogenetic and Muscular Disorders Research
- Peripheral Neuropathies and Disorders
- Psoriasis: Treatment and Pathogenesis
- Pituitary Gland Disorders and Treatments
- Synthetic Organic Chemistry Methods
- PI3K/AKT/mTOR signaling in cancer
- Hereditary Neurological Disorders
- Acute Ischemic Stroke Management
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Prosthetics and Rehabilitation Robotics
- Traumatic Brain Injury Research
- Mathematical Biology Tumor Growth
- Whipple's Disease and Interleukins
- Therapeutic Uses of Natural Elements
- Trauma and Emergency Care Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular and exercise physiology
- Exercise and Physiological Responses
- Genomics, phytochemicals, and oxidative stress
Cairo University
2007-2024
Modern University for Information and Technology
2021-2024
Royal Hallamshire Hospital
2009-2023
Sheffield Teaching Hospitals NHS Foundation Trust
2010-2023
University of Oslo
2021
Alexandria University
2020-2021
Diakonhjemmet Hospital
2021
University of Nottingham
2021
King Abdulaziz University
2021
Neurosciences Institute
2020
Gene expression profiling has been used previously with spinal cord homogenates and laser capture microdissected motor neurons to determine the mechanisms involved in neurodegeneration amyotrophic lateral sclerosis. However, while cellular animal model work focused on superoxide dismutase 1-related sclerosis, transcriptional profile of human mutant 1 remained undiscovered. The aim this study was apply gene captured from sclerosis neurologically normal control cases, order those pathways...
<h3>Background</h3> Crossover in the pathogenic mechanisms of amyotrophic lateral sclerosis (ALS) and multiple (MS) has been described but is poorly understood. A GGGGCC hexanucleotide repeat expansion <i>C9ORF72</i> recently identified a significant proportion patients with ALS. <h3>Methods</h3> In approximately 650 diagnosed ALS from North England we seven who initially presented MS. DNA obtained five MS-ALS 215 MS alone was screened for expansion. Post-mortem material examined two MS-ALS....
Abstract PTEN (phosphatase and tensin homologue deleted in chromosome 10) was first identified as a candidate tumour suppressor gene located on 10q23. It is considered one of the most frequently mutated genes human malignancies. Emerging evidence shows that biological function extends beyond its activity. In central nervous system crucial regulator neuronal development, survival, axonal regeneration synaptic plasticity. Furthermore, has been linked to pathogenesis neurodegenerative disorders...
Remote ischaemic preconditioning (RIPC) is the exposure of body parts to brief periods circulatory occlusion and reperfusion. Recent studies have also shown that RIPC can improve exercise performance in healthy individuals.This study aimed assess effect on walking people with multiple sclerosis (MS).This was a double-blind randomised controlled clinical trial. We used three cycles delivered by occluding upper arm blood pressure (BP) cuff inflated 30 mm Hg above systolic BP. In patients sham...
Background. Type 2 diabetes mellitus (T2DM) is a chronic disease with many dramatic complications. It has also been suggested that altered intestinal microbiota leads to increased permeability and mucosal immune response, contributing the development of diabetes. We aimed investigate effect introduction probiotic products on glycemic control inflammatory markers among patients T2DM. Methods. The present work was carried 150 studied were subjected full history taking, clinical examination...
Background. The aim of this study is to evaluate the metabolic effects Ramadan fasting on patients with type 2 diabetes, and their relation glycemic control, risk hypoglycemia, as well any possible diabetic complications. Methods. 300 subjects diabetes were assessed regarding hypoglycemia examination included measurement body mass index (BMI), blood pressure, foot for sensory loss peripheral vascular disease (PVD) by assessing vibration sense calculating ankle-brachial (ABI) respectively....
INTRODUCTION. Post-stroke dysphagia is reported in 30–50 % of stroke population. It increases mortality rate and leads to serious complications such as expiratory muscle affection which a major cause defective swallowing ineffective airway protection. Expiratory strength training (EMST) functional electrical stimulation (FES) are recommended techniques improve muscles performance.
 AIM. To compare the effect EMST that FES on pulmonary functions acute patients.
 MATERIAL AND...
Background. The incidence of type 2 diabetes mellitus (T2DM) has increased over the past years and early identification management its complications especially diabetic kidney disease (DKD) is great importance. T2DM DKD are multifactorial etiology with contribution genetic environmental factors. We aimed to study expression ABCC8 Notch genes in patients find their association DKD. Methods. present work was carried on 80 (40 40 without DKD) healthy subjects as a control group. Real time...
Background: Unloading the diaphragm by mechanical ventilation results in diaphragmatic dysfunction and atrophy, a condition recognized critical care settings as ventilator-induced (VIDD).This contributes to prolonged ventilation, extubation failure higher risk of mortality. The aim Study:The current study aimed investigate effectiveness inspiratory muscle training preventing or reversing atrophy mechanically ventilated COVID-19 patients.Materials Methods: 55 intubated, patients with hypoxic...
Psychological stressors have been reported to precede the onset of psoriasis in 44% patients, initiate recurrent skin flares 88% psoriatic and may worsen severity even lengthen time disease clearance.This study aimed to: 1. Identifying types stressors, which are related forms clinical profile psoriasis, 2. psychosocial factors Egyptian sample.Methods: One hundred fifty patients randamised samples were collected from dermatological out-patient clinic affiliated ministry health universities...