- Head and Neck Surgical Oncology
- Meningioma and schwannoma management
- Pituitary Gland Disorders and Treatments
- Cerebrospinal fluid and hydrocephalus
- Sinusitis and nasal conditions
- Surgical Simulation and Training
- Anatomy and Medical Technology
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Facial Trauma and Fracture Management
- Craniofacial Disorders and Treatments
- Augmented Reality Applications
- Neurofibromatosis and Schwannoma Cases
- Neurosurgical Procedures and Complications
- Spinal Dysraphism and Malformations
- Ophthalmology and Eye Disorders
- Spinal Fractures and Fixation Techniques
- Glioma Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Soft tissue tumor case studies
- Cerebral Venous Sinus Thrombosis
European Biomedical Research Institute of Salerno
2022-2025
Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona
2023-2025
University of Salerno
2023-2025
University of Naples Federico II
2008-2024
Tokuda Hospital
2024
Acıbadem Adana Hospital
2024
Italian Society of Physiotherapy
2024
Azienda Ospedaliera Universitaria Pisana
2017-2024
University of Pisa
2024
Universitat de Barcelona
2009-2023
OBJECTIVE The superior eyelid endoscopic transorbital approach (SETOA) provides a direct and short minimally invasive route to the anterior middle skull base. Nevertheless, it uses narrow corridor that limits its angles of attack. aim this study was evaluate feasibility potential benefits an "extended" conservative variant "standard" approach—termed "open-door"—to enhance exposure lesions affecting paramedian aspect cranial fossae. METHODS First, authors described technical nuances open-door...
Endoscopic skull base surgery is now the preferred treatment option to remove tumors.To evaluate patient's sense of smell and mucociliary clearance time (MCT) after surgery.Patients with pituitary adenoma underwent a transnasal transsphenoidal endoscopic approach (TTEA group, n = 36), whereas patients other benign parasellar tumors an expanded endonasal (EEA 14) vascularized septal flap. Assessment symptoms (Visual Analogue Scale), olfactometry (Barcelona Smell Test, BAST-24), MCT (saccharin...
OBJECTIVE Exposure of the cavernous sinus is technically challenging. The most common surgical approaches use well-known variations standard frontotemporal craniotomy. In this paper authors describe a novel ventral route that enters lateral wall through an interdural corridor includes removal greater sphenoid wing via purely endoscopic transorbital pathway. METHODS Five human cadaveric heads (10 sides) were dissected at Laboratory Surgical NeuroAnatomy University Barcelona. To expose sinus,...
OBJECTIVERecent studies have proposed the superior eyelid endoscopic transorbital approach as a new minimally invasive route to access orbital lesions, mostly in otolaryngology and maxillofacial surgeries. The authors undertook this anatomical study order contribute neurosurgical perspective, exploring anterior middle cranial fossa areas through purely trajectory.METHODSAnatomical dissections were performed 10 human cadaveric heads (20 sides) using 0° 30° endoscopes. A step-by-step...
The recent development of the superior eyelid endoscopic transorbital approach (SETOA) offered a new route for management cavernous sinus and middle cranial fossa tumors. As result, constant anatomic landmark surgical pathway after drilling medial edge greater sphenoid wing (GSW) is represented by triangular-shaped bone ridge appearing as "crest."To perform an study to define this landmark, named "sagittal crest" (SC) seen from view.Four adult cadaveric specimens (8 sides) were dissected...
Abstract BACKGROUND Feasibility and safety of spheno-orbital meningioma resection by means endoscopic-assisted transorbital route. OBJECTIVE To evaluate the feasibility outcomes endoscopic management selected meningiomas. As secondary aims, symptom improvement tumor volume removed were evaluated. METHODS Retrospective chart evaluation patients with meningiomas treated superior eyelid approach in 3 referral centers over last 4 yr. RESULTS Fourteen cases included this study. In patients, was...
Neurosurgical indications for the superior eyelid transorbital endoscopic approach (SETOA) are rapidly expanding over last years. Nevertheless, as any new technique, a detailed knowledge of anatomy surgical target area, operative corridor, and specific landmark from this different perspective is required safest successful surgery. Therefore, aim study to provide, through anatomical dissections, investigation revealed by SETOA via anterolateral triangle middle cranial fossa. We also sought...
BACKGROUND AND OBJECTIVES: McCarty keyhole (MCK) is the most important entry point during orbitocranial and cranio-orbital approaches; nevertheless, its anatomic coordinates have never been detailedly described from transorbital perspective. To provide spatial for intraorbital projection of “mirror” MCK by using well-established main anatomic-surgical bony landmarks met along corridor. METHODS: was identified in 15 adult dry skulls (30 sides) on exocranial surface pterional region based...
Virtual reality-based learning of neuroanatomy is a new feasible method to explore, visualize, and dissect interactively complex anatomic regions. We provide interactive photorealistic three-dimensional (3D) model sellar region microsurgical anatomy that allows side-by-side views exocranial endocranial surfaces be explored, with the aim assisting young neurosurgery residents in this region.
The removal of clival lesions, mainly those located intradurally and with a limited lateral extension, may be challenging because the lack surgical corridor that would allow exposure entire lesion surface. In this anatomic study, we explored clival/petroclival area cerebellopontine angle via both endonasal retrosigmoid endoscopic routes, aiming to describe respective degree visual limitations.Twelve fresh cadaver heads were positioned simulate semisitting position, thus enabling use which...
OBJECTIVE Different surgical routes have been used over the years to achieve adequate decompression of optic nerve in its canal including, more recently, endoscopic approaches performed either through endonasal corridor or transorbital one. The present study aimed detail and quantify amount bone removal around canal, achievable via medial-to-lateral lateral-to-medial trajectories. METHODS Five human cadaveric heads (10 sides) were dissected at Laboratory Surgical Neuroanatomy University...
Endoscopic transsphenoidal surgery is currently the optimal treatment for skull base tumors. This study was designed to assess patient's sinonasal symptoms and quality of life (QoL) after resection pituitary adenoma or tumors using vascularized septal flap (VSF) reconstruction.Patients with underwent transnasal endoscopic approach (TTEA; n = 38), patients other benign parasellar expanded endonasal (EEA; 17) VSF. Assessment QoL by 36-item Short-Form (SF-36) 31-item Rhinosinusitis Outcome...
Over the years, Meckel's cave pathologies have been judged off-limits because of high rates morbidity. Even though several studies defined various surgical routes with tolerable morbidity and mortality rates, controversies related to optimal avenue treat different categories cavernous sinus neoplasms persist. With unceasing energy cultivate minimally invasive neurosurgical approaches, endoscopic endonasal route has tested, approach effectively performed, provide a valid window these areas....
Background: The cavernous sinus (CS) is a highly vulnerable anatomical space, mainly due to the neurovascular structures that it contains; therefore, detailed knowledge of its anatomy mandatory for surgical unlocking. In this study, we compared region from different endoscopic and microsurgical operative corridors, further focusing on corresponding anatomic landmarks encountered along these routes. Furthermore, tried define safe entry zones venous space three provide indications regarding...
To scrutinize and compare the accuracy of measurements obtained from photogrammetric models against direct taken on dry skulls, with aim to verify feasibility photogrammetry for quantitative analysis in microsurgical neuroanatomy.
Introduction: Endoscopic endonasal approaches are a crucial part of the armamentarium modern skull base surgeon as they afford direct access to deep-seated structures and with excellent visualization maneuverability. Nonetheless, there is steep learning curve for these approaches, comprehensive understanding bony drilling dissection required perform various EEAs what expose has traditionally hours dedicated practice in cadaveric labs. Thus we aim create an endoscopic photogrammetry atlas...