A5018771548- Retinal and Optic Conditions
- Multiple Sclerosis Research Studies
- Ophthalmology and Eye Disorders
- Ocular Diseases and Behçet’s Syndrome
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Facial Rejuvenation and Surgery Techniques
- Systemic Lupus Erythematosus Research
- Ocular Infections and Treatments
- Ocular Disorders and Treatments
- COVID-19 and healthcare impacts
- IgG4-Related and Inflammatory Diseases
- Otitis Media and Relapsing Polychondritis
- Dermatologic Treatments and Research
- Pituitary Gland Disorders and Treatments
- Corneal surgery and disorders
- Cerebral Venous Sinus Thrombosis
- Corneal Surgery and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Head and Neck Surgical Oncology
- Reconstructive Facial Surgery Techniques
- Optical Coherence Tomography Applications
- Ophthalmology and Visual Health Research
- Meningioma and schwannoma management
- Cerebrospinal fluid and hydrocephalus
Universidad de Granada
2021-2025
Instituto de Investigación Biosanitaria de Granada
2021-2025
Hospital Universitario Virgen de las Nieves
2020-2025
Universidad de Málaga
2023
University College London
2023
Moorfields Eye Hospital
2023
Weatherford College
2022
Hospital Clínic de Barcelona
2009-2020
Universitat de Barcelona
2009-2019
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2013-2017
Objective We set out to assess the dynamics of retinal injury after acute optic neuritis (ON) and their association with clinical visual outcomes. Methods Thirty‐one consecutive patients ON were prospectively analyzed over a 6‐month follow‐up period. Each month, we used optical coherence tomography (OCT) thickness peripapillary nerve fiber layer (pRNFL) segmented macular layers, as well high‐contrast acuity, low‐contrast acuity (LCVA), color (CVA), fields (VF). Results In this prospective...
Over the years, Meckel's cave pathologies have been judged off-limits because of high rates morbidity. Even though several studies defined various surgical routes with tolerable morbidity and mortality rates, controversies related to optimal avenue treat different categories cavernous sinus neoplasms persist. With unceasing energy cultivate minimally invasive neurosurgical approaches, endoscopic endonasal route has tested, approach effectively performed, provide a valid window these areas....
Background: This study introduces a novel surgical approach, the Marginal Approach for Releasing lid with Closure Handling technique (MARCH technique), single-step sparing tissue technique, reconstruction of medium to large full-thickness lower eyelid defects and its outcomes. Methods: The research considers single-centre case series description MARCH technique. Patients defect underwent this which combines inferior cantholysis, splitting lamellae island or advancement flaps. Demographic...
To assess the association of primary retinal inflammation, namely periphlebitis (RP) and microcystic macular edema, with clinical, brain, imaging biomarkers multiple sclerosis (MS) severity.One hundred patients MS underwent a neurologic ophthalmic examination, MRI, optical coherence tomography. Disability was assessed using Expanded Status Scale at baseline after 1-year follow-up. The normalized brain volume, normal-appearing gray matter T1 lesion volume were as radiologic disease severity....
Background: Colour vision assessment correlates with damage of the visual pathway and might be informative overall brain in multiple sclerosis (MS). Objective: The objective this paper is to investigate association between impaired colour disease severity. Methods: We performed neurological ophthalmic examinations, as well magnetic resonance imaging (MRI) optical coherence tomography (OCT) analyses, on 108 MS patients, both at baseline after a follow-up one year. was evaluated by Hardy, Rand...
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory central nervous system disease that preferentially affects the optic nerve and spinal cord [Wingerchuk et al. 2015]. Up to 70% of patients with NMOSD have antibodies aquaporin-4 (AQP4-IgG). AQP4 expressed in astrocytes Muller cells eye. A subgroup AQP4-IgG-seronegative has myelin oligodendrocyte glycoprotein (MOG-IgG), neuritis (ON) relapses are also frequent these [Hoftberger 2015]. We hypothesize retinal injury may be...
Patients presenting with visual disturbances often require a neuroimaging approach. The spectrum of includes three main categories: vision impairment, ocular motility dysfunction, and abnormal pupillary response. Decreased is usually due to an eye abnormality. However, it can also be related other disorders affecting the pathway, from retina occipital lobe. Ocular dysfunction may follow cranial nerves responsible for movements (ie, oculomotor, trochlear, abducens nerves); any abnormality...
Multiple Sclerosis (MS) is an immune-mediated disease of the Central Nervous System with two major underlying etiopathogenic processes: inflammation and neurodegeneration. The latter determines prognosis this disease. MS main cause non-traumatic disability in middle-aged populations. MS-VisualPath Cohort was set up to study neurodegenerative component using advanced imaging techniques by focusing on analysis visual pathway a population Barcelona, Spain. We started recruitment patients early...
Neuroprotective and remyelinating therapies are required for multiple sclerosis (MS), acute optic neuritis (AON) is a potential condition to evaluate such treatments.To comprehensively assess key biological methodological aspects of AON trials testing neuroprotection remyelination in MS.The AON-VisualPath prospective cohort study was conducted from February 2011 November 2018 at the Hospital Clinic University Barcelona, Spain. Consecutive patients with were prospectively enrolled followed up...
Visual recovery after optic neuritis (ON) used to be defined as good, although patients frequently complain of poor vision.We carried out a prospective study on 38 consecutive with acute ON followed monthly for 6 months and evaluated high- low-contrast visual acuity (HCVA LCVA, respectively), quality vision (National Eye Institute Function Questionnaire-25 (NEI-VFQ-25)), fields, retinal thickness by spectral domain optical coherence tomography (OCT).We found significant impaired LCVA color...
We report the case of a 52-year-old woman with advanced colorectal cancer who was treated oxaliplatin on FOLFOX schedule. After 3 cycles chemotherapy, she started to complain visual loss, altered color vision and neurological symptoms. Due suspicion ocular toxicity, antineoplastic treatment stopped. Her field showed concentric bilateral scotoma electrooculogram test revealed severe impairment retinal pigment epithelium. Visual acuity, recovered completely 8 months later, although remained...
Orbital inflammatory disease (OID) includes all processes affecting the orbit. Although several aetiologies are recognised, a cause may not be elucidated. We describe 2 cases in which drugs (hyaluronidase and zoledronic acid) were of OID. In patients with clinical picture OID simulating an orbital cellulitis, recent drug history should considered as possible aetiology, treatment steroids or without biopsy after infection has been excluded.
<h3>Importance</h3> Patients with benign essential blepharospasm or hemifacial spasm are known to use botulinum toxin injections and alleviating maneuvers help control their symptoms. The clinical correlates between the of not well established. <h3>Objective</h3> To determine whether for disease severity treatment. <h3>Design, Setting, Participants</h3> A prospective cross-sectional observational study (designed in September 2013) 74 patients 56 who were consecutively recruited from adnexal...
Travoprost is a prostaglandin analog used in the treatment of open-angle glaucoma. This drug safe and efficacious has low incidence systemic local side effects. Common effects are conjunctival hyperemia, iris pigmentation, hypertrichosis eyelashes. The authors present case patient who developed marked cheek vellus 3 months after starting with travoprost.
The aims of this article are twofold: (1) to provide the facial plastic surgeon with a comprehensive and up-to-date overview periocular anatomy including brow, midface, temporal region (2) highlight important anatomical relationships that must be appreciated in order achieve best possible functional aesthetic surgical outcomes.
There are currently two authorized vaccines against herpes zoster (HZ) that have been shown to be safe and effective in its prevention: Zostavax, a vaccine live (ZVL), Shingrix, recombinant Vaccine (RZV). Because ophthalmologists work with vision-threatening complications of zoster, such as ophthalmicus (HZO), they good position advocate for vaccination. Our aim was determine the current knowledge among Spanish about effectiveness available HZ. A Google Forms questionnaire created used...
A 57-year-old-man treated with deep brain stimulation (DBS) of both subthalamic nuclei for advanced Parkinson disease developed a hemorrhage near the site one DBS electrodes 9 months after implantation. The caused vertical diplopia from skew deviation. Examination also disclosed evidence ipsiversive binocular torsion and right head tilt, constituting an ocular tilt reaction (OTR). Fourteen later, he was still symptomatic diplopia. An OTR has not previously been reported as delayed complication DBS.
We performed an in-depth study of the neuro-ophthalmologic signs and symptoms a rare but fatal disease known as primary diffuse leptomeningeal gliomatosis (PDLG). Two new cases PDLG are described, 22 published reviewed. Papilledema sixth nerve palsy most common neuro-ophthalmic findings. Other abnormalities include third fourth palsies, nystagmus, vision loss. Involvement visual system may be part initial presentation PDLG.