Edward J. Casswell

ORCID: 0000-0002-8837-9910
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About
Contact & Profiles
Research Areas
  • Intraocular Surgery and Lenses
  • Retinal and Macular Surgery
  • Traumatic Ocular and Foreign Body Injuries
  • Glaucoma and retinal disorders
  • Retinal and Optic Conditions
  • Retinal Diseases and Treatments
  • Intracranial Aneurysms: Treatment and Complications
  • Surgical Simulation and Training
  • Corneal Surgery and Treatments
  • Vascular Malformations Diagnosis and Treatment
  • Facial Trauma and Fracture Management
  • Cerebrovascular and Carotid Artery Diseases
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • ECG Monitoring and Analysis
  • Corneal surgery and disorders
  • Facial Rejuvenation and Surgery Techniques
  • Dermatologic Treatments and Research
  • Ocular Oncology and Treatments
  • Retinal Imaging and Analysis
  • Ocular Diseases and Behçet’s Syndrome
  • Facial Nerve Paralysis Treatment and Research
  • Ocular Surface and Contact Lens
  • Botulinum Toxin and Related Neurological Disorders
  • Ophthalmology and Eye Disorders
  • Telemedicine and Telehealth Implementation

Moorfields Eye Hospital
2014-2024

University College London
2014-2024

Moorfields Eye Hospital NHS Foundation Trust
2015-2024

University Hospitals Sussex NHS Foundation Trust
2023-2024

Sussex Eye Hospital
2023-2024

Ophthalmology Associates (United States)
2023

ViteroRetinal Surgery
2023

Birmingham Accident Hospital
2020

Institute of Ophthalmology
2020

Government of Western Australia Department of Health
2018

Background The COVID-19 crisis forced hospitals in the UK dramatically to reduce outpatient activity. To provide continuity of care and assist patients reluctant or unable leave their homes, video consultations were rapidly implemented across routine emergency ophthalmology services. Objective describe deployment scaling a large volume teleophthalmology using consultation platform ‘Attend Anywhere’ Moorfields Eye Hospital’s accident (A&E) department (London, UK). Method Patient...

10.1136/bmjhci-2020-100179 article EN cc-by-nc BMJ Health & Care Informatics 2020-08-01

<h3>Importance</h3> A lack of consensus exists with regard to the optimal positioning regimen for patients after macula-involving retinal detachment (RD) repair. <h3>Objective</h3> To evaluate effect face-down vs support-the-break on displacement and distortion RD <h3>Design, Setting, Participants</h3> prospective 6-month single-masked randomized clinical trial was conducted at a multicenter tertiary referral setting from May 16, 2016, 1, 2018. Inclusion criteria were fovea-involving...

10.1001/jamaophthalmol.2020.0997 article EN JAMA Ophthalmology 2020-04-16

<h3>Aims</h3> To investigate whether ophthalmology trainees are able to assess their own competence in cataract surgery and this judgement improves as they progress through training. <h3>Methods</h3> A prospective, blinded, single-centre comparative study of trainee surgeons was performed. 16 junior (150–499 operations) senior (&gt;500 were recruited. They performed a single videotaped operation filled the validated Objective Structured Assessment Cataract Surgical Skill (OSACSS) assessment...

10.1136/bjophthalmol-2015-307307 article EN British Journal of Ophthalmology 2015-09-07

<h3>Importance</h3> Patients with benign essential blepharospasm or hemifacial spasm are known to use botulinum toxin injections and alleviating maneuvers help control their symptoms. The clinical correlates between the of not well established. <h3>Objective</h3> To determine whether for disease severity treatment. <h3>Design, Setting, Participants</h3> A prospective cross-sectional observational study (designed in September 2013) 74 patients 56 who were consecutively recruited from adnexal...

10.1001/jamaophthalmol.2016.3277 article EN JAMA Ophthalmology 2016-09-08

Purpose: Long-term study to evaluate the clinical and surgical outcomes of SB surgery for primary rhegmatogenous retinal detachment (RRD) at a large tertiary eye center. Methods: Non-comparative, retrospective case series 589 eyes 569 patients with RRD who underwent between 2004 2022 median follow-up 6 months. Main outcome measures were best-corrected visual acuity (BCVA), outcomes, complications, classification RRD. Results: At baseline, 447/589 (76.1%), round hole-RRD 133/589 (22.7%)...

10.1097/iae.0000000000004082 article EN Retina 2024-03-01

&lt;b&gt;&lt;i&gt;Purpose:&lt;/i&gt;&lt;/b&gt; The reported incidence of postretinal detachment (RD) macular displacement varies markedly (14–72%). This may in part be due to the imaging modalities used. We compared ability 2 types fundus autofluorescence (FAF) detect this phenomenon. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; Prospective study 70 eyes with macula-involving RDs. 8 weeks postoperatively, patients underwent FAF machines: a confocal scanning laser ophthalmoscope (cSLO) and...

10.1159/000504713 article EN Ophthalmologica 2019-12-11

Background/aims To investigate the clinical effectiveness of adjunctive triamcinolone acetonide (TA) given at time vitreoretinal surgery following open globe trauma (OGT). Methods A phase 3, multicentre, double-masked randomised controlled trial patients undergoing vitrectomy OGT comparing TA (intravitreal and subtenons) against standard care (2014–2020). The primary outcome was proportion with least 10 Early Treatment Diabetic Retinopathy Study (ETDRS) letter improvement in corrected visual...

10.1136/bjo-2022-322787 article EN British Journal of Ophthalmology 2023-02-27

Ocriplasmin is a protease which has been approved for the treatment of symptomatic vitreomacular adhesion (VMA). A 63-year-old presented with blurred vision in left eye and best corrected visual acuity 6/18. Optical coherence tomography revealed VMA an underlying macular hole she subsequently underwent intravitreal ocriplasmin injection. One week after injection, had released but enlargement drop her BCVA to 6/60. This persisted at 1 month It important warn patients that may lead their...

10.1155/2014/403461 article EN cc-by Case Reports in Ophthalmological Medicine 2014-01-01

Background Eyes sustaining open globe trauma are at high risk of severe visual impairment. Proliferative vitreoretinopathy is the most common cause retinal detachment and loss in eyes with trauma. There evidence from experimental studies pilot clinical trials that use adjunctive steroid medication triamcinolone acetonide can reduce incidence proliferative improve outcomes surgery for Objective The Adjunctive Steroid Combination Ocular Trauma or ASCOT study aimed to investigate effectiveness...

10.3310/gnbj1387 article EN publisher-specific-oa Health Technology Assessment 2023-07-01

Posterior hyaloid removal during pars plana vitrectomy and lensectomy for ectopia lentis is commonly performed, but may increase the risk of intraoperative retinal breaks postoperative detachment. This study evaluated outcomes after with or without posterior removal.This retrospective observational cohort included cases that underwent (2005-2014), induction a vitreous detachment (PVD). The primary outcome was secondary were incidence iatrogenic breaks, change in visual acuity.Twenty-six...

10.1097/iae.0000000000001534 article EN Retina 2017-02-16

To establish the level of confidence amongst UK ophthalmology specialist registrars (residents) in managing posterior capsule rupture (PCR) during cataract surgery.An online nine-item questionnaire was distributed to all registrars, recruited nationwide via regional representatives. Data collected included stage training, number completed operations, cumulative PCR rate, PCRs independently managed, understanding vitrectomy settings and fluidic parameters access simulation. Respondents...

10.1007/s40123-021-00425-3 article EN cc-by-nc Ophthalmology and Therapy 2021-11-19

Purpose: Paraneoplastic ocular inflammation can be associated with the autoantibody against collapsin response-mediator protein-5 (anti-CRMP-5). We describe clinical and histological features of 2 rare cases small cell lung carcinoma (SCLC) presenting intraocular inflammation: first was anti-CRMP-5 positive second preceded auto-antibody's discovery but remarkably similar features. The previously unreported retinal histology is described.Methods: Case notes review.Results: Both presented...

10.3109/09273948.2015.1012296 article EN Ocular Immunology and Inflammation 2015-07-14

Casswell, Edward J. MBBS; Bowes, Oliver Barsam, Allon FRCOphth; Perry, Henry D. MD Author Information

10.1097/ico.0000000000000835 article EN Cornea 2016-04-19

To describe the widefield spectral-domain optical coherence tomography features of peripheral round retinal holes, with or without associated detachment (RD).Retrospective, observational study 28 eyes and RD. Patients underwent imaging a 50-degree (Heidelberg Engineering, Germany) Optos ultra-widefield systems (Optos, United Kingdom).Vitreous attachment at site hole was detected in 27/28 (96.4%) cases. Cases were split into three groups: RHs RD (n = 12); subretinal fluid 5), flat 11),...

10.1097/iae.0000000000002133 article EN Retina 2018-03-04

Objectives To understand the incidence, causes, management and outcomes of intentional (assault) unintentional severe ocular chemical injuries (SOCI) at an urban tertiary referral centre in UK. Design Retrospective observational study. Setting A London ophthalmic centre, Moorfields Eye Hospital. Participants All cases SOCI presenting between 1 September 2011 31 August 2014 were identified. The definition was grade 3 or 4 on Hughes-Roper-Hall classification system. We identified 25 (6...

10.1136/bmjopen-2020-038109 article EN cc-by BMJ Open 2020-10-01

A 74-year-old man developed sudden onset of painless persistent partial loss vision in the right eye 3 days after total knee replacement. The initial investigation was for amaurosis fugax with a normal CT scan brain but carotid Doppler confirmed &gt;90% stenosis internal artery. Urgent ophthalmological review anterior ischaemic optic neuropathy. Subsequently, he lost his completely eye. He had previous high risk hemispheric transient attack reported as normal.

10.1136/bcr.08.2011.4725 article EN BMJ Case Reports 2011-12-05

Background In the United Kingdom, it is estimated that 5,000 patients sustain eye injuries or ocular trauma requiring hospital admission annually, of which 250 will be permanently blinded. This study explores cost-effectiveness Adjunctive Steroid Combination in Ocular Trauma (ASCOT) given during surgery versus standard treatment vitreoretinal with open globe trauma. Methods economic evaluation was embedded alongside ASCOT RCT (ClinicalTrials.gov Identifier: NCT02873026). We conducted a...

10.1371/journal.pone.0311158 article EN cc-by PLoS ONE 2024-12-16
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