A5035020241- Fungal Biology and Applications
- Microbial Natural Products and Biosynthesis
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Genomics and Phylogenetic Studies
- Cancer-related molecular mechanisms research
- Mycorrhizal Fungi and Plant Interactions
- Plant-Microbe Interactions and Immunity
- Plant Gene Expression Analysis
- Microbial Metabolism and Applications
- Pharmacological Effects of Natural Compounds
- Natural product bioactivities and synthesis
- Phytochemistry and Bioactivity Studies
- Plant Stress Responses and Tolerance
- Plant Pathogens and Fungal Diseases
- Phytochemical compounds biological activities
- Circular RNAs in diseases
- Herbal Medicine Research Studies
- Plant biochemistry and biosynthesis
- Phytochemistry and Biological Activities
- Autophagy in Disease and Therapy
- Ginseng Biological Effects and Applications
- Biochemical and Structural Characterization
- Medicinal Plants and Bioactive Compounds
- Fungal and yeast genetics research
Binzhou University
2024-2025
Binzhou Medical University
2024-2025
Shenyang Pharmaceutical University
2013-2025
Fuling Center Hospital of Chongqing
2025
Chongqing University
2025
Chongqing Medical University
2023-2025
Anhui Agricultural University
2025
Shanghai Academy of Agricultural Sciences
2016-2024
Jimei University
2024
Shanghai Jiao Tong University
2020-2023
The nuclear ribosomal DNA internal transcribed spacer (ITS) has been widely used to assess the fungal composition in different environments by deep sequencing. To evaluate ITS analysis of diversity, comparisons clustering and taxonomy generated sequencing with portions whole fragment were conducted this study. For a total 83,120 full-length sequences obtained from UNITE database, it was found that, on average, ITS1 varied more than ITS2 within kingdom Fungi; variation included length GC...
Kiwifruit (Actinidia spp.) is a climacteric fruit with high sensitivity to ethylene, influenced by multiple ethylene-responsive structural genes and transcription factors. However, the roles of other post-transcriptional regulators (e.g. miRNAs) necessary for ripening remain elusive. High-throughput sequencing sRNAome, degradome transcriptome methods were used identify further contributors control in kiwifruit (A. deliciosa cv 'Hayward'). Two NAM/ATAF/CUC domain factors (AdNAC6 AdNAC7), both...
Progression to castration resistance is the leading cause of death in prostate cancer patients. Long non-coding RNAs (lncRNAs) have recently become a focal point regulation development. However, few lncRNAs associated with castration-resistant (CRPC) been reported. Firstly, we explore CRPC by RNA sequencing and validated using quantitative polymerase chain reaction (qRT-PCR) fluorescence situ hybridization (RNA-FISH). The clinical significance FLJ was evaluated collected cohort. Functional...
Changes in skin colour, as a visual cue for fruit ripeness, are important physiological markers many crops including tomato, banana and grape. In kiwifruit, the remains brown during ripening, but de-greening of pericarp occurs to reveal accumulated carotenoids anthocyanins gold- red-fleshed cultivars. this study, analysis inner outer Actinidia chinensis 'Hongyang' revealed faster chlorophyll degradation pericarp, compared with pericarp. Based on transcriptome analysis, two...
Cross-talk between various hormones is important in regulating many aspects of plant growth, development, and senescence, including fruit ripening. Here, exogenous ethylene (ETH, 100 μL/L, 12 h) rapidly accelerated 'Hayward' kiwifruit (Actinidia deliciosa) softening production was enhanced by supplementing with continuous treatment methyl jasmonate (MeJA, μM/L, (ETH+MeJA). ETH+MeJA ACC synthase (ACS) activities 1-aminocyclopropane-1-carboxylic acid (ACC) accumulation but not oxidase (ACO)...
Streptomycetes from the rhizospheric soils are a rich resource of novel secondary metabolites with various biological activities. However, there is still little information related to isolation, antimicrobial activity and biosynthetic potential for polyketide non-ribosomal peptide discovery associated streptomycetes Panax notoginseng. Thus, aims present study (i) identify culturable soil P. notoginseng by 16S rRNA gene, (ii) evaluate activities isolates analyze gene encoding synthases (PKSs)...
CRISPR-Cas immunity systems safeguard prokaryotic genomes by inhibiting the invasion of mobile genetic elements. Here, we screened genomic sequences and identified multiple natural transpositions insertion (ISs) into cas genes, thus inactivating defenses. We then generated an IS-trapping system, using Escherichia coli strains with various ISs inducible nuclease, to monitor IS insertions genes following induction double-strand DNA breakage as a physiological host stress. events mediated...
Prostate cancer (PCa) is a common malignant in elderly males Western countries. Whole-genome sequencing confirmed that long non-coding RNAs (lncRNAs) are frequently altered castration-resistant prostate (CRPC) and promote drug resistance to therapy. Therefore, elucidating the prospective role of lncRNAs PCa oncogenesis progression remarkable clinical significance. In this study, gene expression tissues was determined using RNA-sequencing datasets, diagnostic prognostic values CRPC were...
Secondary metabolites with cytotoxic activity, antiviral activity and antimicrobial from the endophytic fungi of <italic>Panax notoginseng</italic>.
Estrogen-related receptor α (ERRα) is dysregulated in many types of cancer and exhibits oncogenic activity by promoting tumorigenesis metastasis cells. However, its defined role renal cell carcinoma (RCC) has not been fully elucidated. To reveal the biological function ERRα determine underlying regulatory mechanism RCC, quantitative proteomics analysis investigation were conducted. The results demonstrated that promoted proliferation RCC cells maintaining lysosome-dependent autophagy flux....
Toxicogenomics, the genome-wide analysis of gene expression to study effect toxicants, has great potential for use in environmental toxicology. Applied standard test organisms, it possible applications aquatic toxicology as a sensitive monitoring tool detect presence contaminants while providing information on mechanisms action these pollutants. We describe complementary DNA (cDNA) microarray fathead minnow (Pimephales promelas) sentinel organism toxicology, better understand toxicity...
Volvariella volvacea (V. volvacea), commonly referred to as Chinese (paddy straw) mushroom, is a basidiomycete with protein-rich volva and pileus. Selecting appropriate reference genes crucial step in the normalization of quantitative real-time PCR data. Therefore, 12 candidate were selected from V. transcriptome based on previous studies then BestKeeper, geNorm, NormFinder used identify stably expressed during different developmental stages conditions. Of genes, SPRY domain protein (SPRYp),...
Two new compounds chetoseminudin F (1) and G (2) together with eleven known were isolated from the solid fermentation products of endophytic fungus Chaetomium sp. SYP-F7950. The structures elucidated by extensive spectroscopic analyses, including 1D 2D NMR, HRFABMS experiments. absolute configurations determined comparing electronic circular dichroism (ECD) spectrum those reported references. A plausible biogenetic pathway for 1-6 9-13 was proposed. These isolates also evaluated their...
Abstract The degradation of chlorophyll during fruit development is essential to reveal a more ‘ripe’ color that signals readiness wild dispersers seeds and the human consumer. Here, comparative biochemical analysis developing Actinidia deliciosa cv. Xuxiang (‘XX’, green-fleshed) chinensis Jinshi No.1 (‘JS’, yellow-fleshed) indicated variation in content major contributor differences flesh color. Four differentially expressed candidate genes were identified: down-regulated AcCRD1 AcPOR1...