A5084081074- Dialysis and Renal Disease Management
- Electrolyte and hormonal disorders
- Renal function and acid-base balance
- Potassium and Related Disorders
- Acute Kidney Injury Research
- Renal Diseases and Glomerulopathies
- Diet and metabolism studies
- Chronic Kidney Disease and Diabetes
- Central Venous Catheters and Hemodialysis
- Hormonal Regulation and Hypertension
- Neurological and metabolic disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- SARS-CoV-2 and COVID-19 Research
- Muscle and Compartmental Disorders
- COVID-19 Clinical Research Studies
- Ion Transport and Channel Regulation
- Renal and Vascular Pathologies
- Bipolar Disorder and Treatment
- Parathyroid Disorders and Treatments
- Erythropoietin and Anemia Treatment
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Renal cell carcinoma treatment
- Organ Donation and Transplantation
- Pharmacological Effects and Toxicity Studies
San Francisco General Hospital
2011-2025
University of California, San Francisco
2009-2023
John H. Stroger, Jr. Hospital of Cook County
2001-2010
Hektoen Institute
2006-2010
University of Illinois Chicago
1994-2006
Rush University Medical Center
2006
Institute for Medical Research
2006
Loyola University Chicago
2000-2002
Alice Ho Miu Ling Nethersole Hospital
2001
University of Colorado Denver
2000
In hyperglycemia, the serum sodium concentration ([Na]S) receives influences from (a) fluid exit intracellular compartment and thirst, which cause [Na]S decreases; (b) osmotic diuresis with sums of urinary plus potassium lower than baseline euglycemic [Na]S, results in a increase; (c), some cases, gains or losses fluid, sodium, through gastrointestinal tract, respiratory skin. Hyperglycemic patients hypernatremia have large deficits body water usually hypovolemia develop severe clinical...
Previously, two reports proposed a four-stream dialysis fluid delivery system consisting of an acid concentrate, base sodium chloride and product water for correcting dysnatremias metabolic acid-base disorders separately, by hemodialysis. This report describes new method the clinical use previously reported to treat concurrently disturbances Pumps attached each concentrate are designed control its flow rate. Formulas were derived determine rate pumps controlling flows (W), (B), (S) any...
Insulin-like growth factor-binding protein-1 (IGFBP-1) is produced by the liver and regulated glucocorticoids insulin at level of gene transcription. To identify DNA sequences mediating effects on IGFBP-1 promoter activity we created luciferase reporter constructs performed transfection studies in H4IIE hepatoma cells. Initial confirmed that functional when inserted correct orientation, but not reverse orientation. Dexamethasone (DEX) increased 10-fold, reversed this effect DEX 85% 8 h. The...
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus anticoagulants, and very high titers antineutrophil cytoplasmic antibodies. Two recent case reports suggest that may also lead renal disease in the form pauci-immune glomerulonephritis. To explore this possibility, we reviewed cases...
A thorough knowledge and understanding of the principles underlying preparation clinical application hemodialysates can help us provide exemplary patient care to individuals having end-stage renal disease. It is prudent be conversant with following: (a) how each ingredient in a dialysate works, (b) circumstances under which concentration an altered, (c) special situations unconventional ingredients introduced into dialysate. The potential enrich dialysates appropriate (such as iron...
Vaccinating patients receiving dialysis may prevent morbidity and mortality in this vulnerable population. The National Forum of End-Stage Renal Disease Networks (the Forum) published a revised vaccination toolkit 2021 to update evidence recommendations on for dialysis. Significant changes the last 10 years include more data supporting use high-dose influenza vaccine, introduction Heplisav-B vaccine hepatitis B, pneumococcal vaccines, including approval PCV15 PCV20 replace PCV13 PPSV23...
Abstract: Expeditious diagnosis of peritonitis remains a significant goal in the management patients maintained on peritoneal dialysis. Several attempts to use leukocyte esterase reagent strips diagnose have been described. In this study we examined usefulness new strip, PeriScreen Test Strip, peritonitis. A series 72 effluent samples obtained from 22 maintenance dialysis is reported. study, test had sensitivity 100% and specificity 98.3% as compared an abnormal count. Thus, believe that...
AA amyloidosis due to subcutaneous injection of drugs abuse has been described in the USA, but all existing literature is from more than 20 years ago. There recent Europe. We have observed a high incidence county hospital San Francisco.Here, we describe 24 patients who had kidney biopsy-proven our 1998 2013. All were thought skin popping illicit after having exhausted intravenous route. These with analysed further.All found hepatitis C infection, hypertension was not common, most advanced...
The relationship between sodium, blood pressure and extracellular volume could not be more pronounced or complex than in a dialysis patient. We review the patients’ sources of sodium exposure form dietary salt intake, medication administration, treatment itself. In addition, roles modalities, hemodialysis types, fluid concentration have on pressure, intradialytic symptoms, interdialytic weight gain affect patient outcomes are discussed. whether restriction (reduced intake), alteration...
Although patients with burns are known to develop hypocalcemia, the development of hypercalcemia has also been reported in a few burn intensive care unit. Here, incidence unit single institution is reviewed. The records all admitted over period 4 years were When looking at select group who have hospitalized for more than weeks, an unusually high was found, especially renal failure (because decreased clearance, prone if another inciting factor present). As previously reported, our consistent...
A patient with three episodes of chest wall abscesses as a result 6 years round-the-clock, uninterrupted (except during bathing) application silicone gel sheets to keloid is described. Two the occurred hot weather. It suggested that, in space beneath sheet, higher humidity and temperature, both generated prolonged sheeting, especially weather, might have caused its neighbouring skin become soggy. This sogginess facilitated bacterial invasion. that some sheeting-free time 24 h period be...