Adelina Mavrea

ORCID: 0000-0002-4032-0899
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About
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Research Areas
  • Infective Endocarditis Diagnosis and Management
  • Cardiovascular Function and Risk Factors
  • Antimicrobial Resistance in Staphylococcus
  • Cardiac Valve Diseases and Treatments
  • Streptococcal Infections and Treatments
  • Cardiac Imaging and Diagnostics
  • Cardiac Structural Anomalies and Repair
  • Lung Cancer Diagnosis and Treatment
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Inflammatory Biomarkers in Disease Prognosis
  • Cardiac, Anesthesia and Surgical Outcomes
  • Heart Failure Treatment and Management
  • Tryptophan and brain disorders
  • Cancer Immunotherapy and Biomarkers
  • Radiomics and Machine Learning in Medical Imaging
  • Cardiac Health and Mental Health
  • Cardiac pacing and defibrillation studies
  • COVID-19 Clinical Research Studies
  • Antifungal resistance and susceptibility
  • Dysphagia Assessment and Management
  • Acute Myocardial Infarction Research
  • COVID-19 and healthcare impacts
  • Antibiotic Use and Resistance
  • Long-Term Effects of COVID-19
  • Cancer survivorship and care

Victor Babeș University of Medicine and Pharmacy Timișoara
2013-2024

City Hospital
2008

Data on bacterial or fungal pathogens and their impact the mortality rates of Western Romanian COVID-19 patients are scarce. As a result, purpose this research was to determine prevalence co- superinfections in adults with COVID-19, hospitalized in-ward settings during second half pandemic, its distribution according sociodemographic clinical conditions. The unicentric retrospective observational study conducted 407 eligible patients. Expectorate sputum selected as sampling technique...

10.3390/pathogens12040620 article EN cc-by Pathogens 2023-04-19

The aim of this study was to assess whether nebivolol treatment could have beneficial effects in the prevention anthracyclines-induced cardiotoxicity.Our prospective included 60 women, mean age 52.6±13 years, with HER2 negative breast cancer, scheduled undergo doxorubicin. patients were randomly divided into two groups: group (n=30) which received 5 mg once daily for duration chemotherapy and control without nebivolol. Cytostatic performed doxorubicin 70 mg/m2 administered intravenously...

10.2147/cmar.s166481 article EN cc-by-nc Cancer Management and Research 2018-07-01

This multicenter, cross-sectional study investigates the potential correlation between development of bronchiectasis after lung resection surgery and health-related quality life (HRQoL) patients. The aims to provide new insights into long-term outcomes patients post-lung surgery. includes adult who underwent for suspicious nodules developed within a follow-up period six months. Bronchiectasis was confirmed by high-resolution computed tomography scans. patient’s (HRQoL), anxiety, depression,...

10.3390/jpm13091310 article EN Journal of Personalized Medicine 2023-08-26

Background and Objectives: Multidrug-resistant microorganisms have made treating bacterial infections challenging. Resistance to antibiotics is expected overcome efforts produce new, effective antibacterial medication that lifesaving in many situations. Infective endocarditis (IE) a life-threatening infection affects 5-15 per 100,000 patients annually requires rapid antibiotic therapy prevent morbidity mortality. Materials Methods: The present research assessed IE cases over five years, from...

10.3390/medicina59030457 article EN cc-by Medicina 2023-02-24

The purpose of this retrospective study was to evaluate the prognostic impact systolic blood pressure (SBP) and heart rate (HR) on in-hospital mortality in ST-segment elevation acute myocardial infarction (STEMI) patients, after primary percutaneous intervention (PCI).The included 294 patients admitted for STEMI. They were divided into five groups according SBP at admission: group I, <105 mmHg; II, 105-125 III, 126-140 IV, 141-158 V, ≥159 mmHg. Increased HR defined as ≥80 beats per minute...

10.2147/tcrm.s141312 article EN cc-by-nc Therapeutics and Clinical Risk Management 2017-08-01

This study aimed to assess the serum levels of intracellular adhesion molecule (sICAM-1), and vascular cell (sVCAM-1), in first psychotic episode schizophrenia (SZ) patients, before after six months antipsychotic treatment.The included 50 patients with a hospitalization for SZ healthy control subjects that were patient-matched regarding age, gender, body mass index smoking status. The evaluation presence cardiovascular risk factors, measurements systolic diastolic blood pressure, index,...

10.2147/ndt.s240349 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2020-02-01

Speckle tracking-echocardiography (STE) is a novel non-invasive imaging tool capable of quantifying myocardial deformation, and thus holds promise in detecting early subclinical injury. This study aimed to evaluate the correlation STE with traditional biomarkers predicting anthracycline-induced cardiotoxicity context varying dosages treatment protocols pediatric hemato-oncology patients. We conducted retrospective involving patients undergoing anthracycline-based chemotherapy. A total 99...

10.3390/children10091479 article EN cc-by Children 2023-08-30

The role of chronic inflammation in the initiation and progression carcinogenesis has been well-established previous studies, particularly stages malignant conversion, invasion, metastasis. This study aimed to explore potential correlation between levels cytokines serum bronchoalveolar lavage fluid (BALF) by comparing their patients with lung cancer those benign diseases. measured concentration IFN-γ, TNF-α, IL-1β, IL-2, IL-4, IL-6, IL-10, IL-12p70, venous blood BALF a total 33 Significant...

10.3390/jpm13060998 article EN Journal of Personalized Medicine 2023-06-14

Background: Heart failure with preserved ejection fraction (HFpEF) is more frequent in the elderly and associated important economic implications because of repetitive prolonged hospitalizations, due to both cardiovascular noncardiovascular causes. Purpose: To identify causes, as well clinical biological markers, that could be used predictors hospital readmissions HFpEF patients aged ≥65 years. Patients methods: Consecutive eligible hospitalized for a first heart (HF) episode were...

10.2147/cia.s83750 article EN cc-by-nc Clinical Interventions in Aging 2015-06-01

Lung cancer is a leading cause of cancer-related mortality worldwide. Identifying novel diagnostic and prognostic biomarkers essential for improving patient outcomes. This study aimed to investigate the predictive role cytokines from bronchoalveolar lavage fluid (BALF) in lung diagnosis prognosis. A prospective was conducted on 33 patients with suspected cancer, divided into inflammatory non-inflammatory BALF groups. Inflammatory markers were assessed, their association risk analyzed using...

10.3390/jpm13060968 article EN Journal of Personalized Medicine 2023-06-08

: Patients aged 80 years and above are at increased risk for severe COVID-19 outcomes. This study aimed to evaluate the prognostic utility of derived neutrophil-to-lymphocyte ratio (dNLR), aspartate-aminotransferase-to-lymphocyte index (ALRI), aspartate-aminotransferase-to-platelet (APRI), systemic immune inflammation (SII) in predicting disease, intensive care unit (ICU) admission, mortality among patients older.

10.3390/healthcare12232429 article EN Healthcare 2024-12-03

Background and Objectives: Pulmonary resections are critical interventions for treating various lung pathologies, both benign malignant. Understanding the impact of these surgeries on patients’ Quality Life (QoL) is essential optimizing care. This study aims to compare Health-Related (HRQoL) psychological well-being in patients who underwent pulmonary versus malignant etiologies. Methods: A cross-sectional was conducted involving 117 resection between January 2022 June 2023. Participants...

10.3390/healthcare13010006 article EN Healthcare 2024-12-24

Lung cancer screening is critical for early detection and management, particularly through the use of computed tomography (CT). This study aims to compare Imaging Reporting Data System (Lung-RADS) Version 2022 with British Thoracic Society (BTS) guidelines in classifying solid pulmonary nodules detected at lung CT examinations. retrospective included 224 patients who underwent between 2016 had a reported nodule. A fellowship-trained thoracic radiologist reviewed images, characterizing by...

10.3390/life15010014 article EN cc-by Life 2024-12-27

Pediatric hemato-oncology patients undergoing anthracycline therapy are at risk of cardiotoxicity, with disease type and treatment intensity potentially affecting cardiac function. Novel echocardiographic measures like speckle tracking echocardiography (STE), global longitudinal strain (GLS), the myocardial performance index (MPI) may predict early changes in function not detected by traditional methods. This study aimed to assess impact cancer protocol on these parameters their potential...

10.3390/diagnostics13172830 article EN cc-by Diagnostics 2023-08-31

Left ventricular (LV) free wall rupture is a potentially lethal mechanical complication after myocardial infarction (MI). Pericardial adhesions or slow extracardiac leak and pericardial inflammation may result in contained cardiac rupture. LV pseudoaneurysm relatively uncommon clinical entity. It occur MI, but also as of infective endocarditis, surgery, trauma. Patients developing MI present angina pectoris signs congestive heart failure (HF) often are asymptomatic. Surgery the treatment...

10.1111/j.1540-8175.2008.00759.x article EN Echocardiography 2008-10-08
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