Liana Dehelean

ORCID: 0000-0003-1160-8575
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About
Contact & Profiles
Research Areas
  • Schizophrenia research and treatment
  • Tryptophan and brain disorders
  • Bipolar Disorder and Treatment
  • Mental Health and Psychiatry
  • Treatment of Major Depression
  • Medication Adherence and Compliance
  • Cardiovascular Syncope and Autonomic Disorders
  • Cardiac electrophysiology and arrhythmias
  • Healthcare professionals’ stress and burnout
  • Obsessive-Compulsive Spectrum Disorders
  • Mental Health Research Topics
  • COVID-19 and Mental Health
  • Cardiovascular Function and Risk Factors
  • Child and Adolescent Psychosocial and Emotional Development
  • Medical Education and Admissions
  • Neurological disorders and treatments
  • Cardiac Health and Mental Health
  • Psychosomatic Disorders and Their Treatments
  • Robotic Mechanisms and Dynamics
  • Electroconvulsive Therapy Studies
  • Thermodynamic and Exergetic Analyses of Power and Cooling Systems
  • Toxoplasma gondii Research Studies
  • Personality Disorders and Psychopathology
  • Analog and Mixed-Signal Circuit Design
  • Personality Traits and Psychology

Victor Babeș University of Medicine and Pharmacy Timișoara
2013-2024

Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara
2008-2024

Cognitive Research (United States)
2021

Polytechnic University of Timişoara
2010-2019

University of Medicine and Pharmacy of Craiova
2016-2019

Spitalul Clinic de Recuperare
2016

Institute e-Austria Timisoara
2012

West University of Timişoara
2008

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces a significant inflammatory response that are amplified by persistent stress. pathophysiology of mental illnesses is explored in terms processes. Thus, anxious, depressed, or psychotic episodes may occur as result metabolic and immunological imbalances, direct their effect on the central nervous system, side COVID-19 medication protocols. As such, primary objective this research to establish if psychological...

10.3390/ijerph19116501 article EN International Journal of Environmental Research and Public Health 2022-05-26

Antipsychotic medication, stress, gender, and age are factors that influence prolactin levels in patients with psychosis. The aim of the study was to investigate level response antipsychotic treatment acute patients, taking into account total duration psychosis.The conducted on 170 schizophrenia spectrum disorders bipolar disorder. Subjects were divided three subgroups according psychosis (less than 5 years, between 10 years more disorder duration). initial under measured, while severity...

10.1371/journal.pone.0228648 article EN cc-by PLoS ONE 2020-02-04

This study aimed to assess the serum levels of intracellular adhesion molecule (sICAM-1), and vascular cell (sVCAM-1), in first psychotic episode schizophrenia (SZ) patients, before after six months antipsychotic treatment.The included 50 patients with a hospitalization for SZ healthy control subjects that were patient-matched regarding age, gender, body mass index smoking status. The evaluation presence cardiovascular risk factors, measurements systolic diastolic blood pressure, index,...

10.2147/ndt.s240349 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2020-02-01

Rational use of medications and monitoring prescriptions in elderly patients is important to decrease the number duration hospitalizations, emergency medical consultations, mortality, as well costs.To identify potentially inappropriate (PIMs) potential prescription omissions (PPOs), determine their prevalence based on Screening Tool Older Persons' Prescriptions (STOPP) v2 criteria Alert doctors Right Treatment (START) for aged >65 years.This cross-sectional study was conducted two rural...

10.2147/cia.s233270 article EN cc-by-nc Clinical Interventions in Aging 2020-03-01

Abstract Background and Hypothesis Meta-analyses have shown that the majority of patients with schizophrenia who not improved after 2 weeks treatment an antipsychotic drug are unlikely to fully respond later. We hypothesized switching another a different receptor binding profile is effective strategy in such situation. Study Design In total, 327 inpatients acute exacerbation were randomized double-blind either olanzapine (5–20 mg/day) or amisulpride (200–800 mg/day). Those had reached at...

10.1093/schbul/sbac068 article EN Schizophrenia Bulletin 2022-07-20

The COVID-19 pandemic has determined an extraordinary challenge to healthcare systems worldwide. circumstances, characterized by elevated stress levels, prolonged working hours, new medical procedures, media attention, and high population expectations, have created extremely stressful situation for professionals. This period offered a unique opportunity examine the system responses of practitioners stress. research aimed identify work-related factors that significantly impact mental health...

10.2147/jmdh.s424563 article EN cc-by-nc Journal of Multidisciplinary Healthcare 2023-08-01

Schizophrenia is one of the most disabling psychiatric diseases. The Brief Psychiatric Rating Scale Extended (BRSE) used to evaluate severity symptoms. Long-acting injectable (LAI) antipsychotics are commonly and preferred over oral antipsychotic medications. A two-center-based cross-sectional study was performed on 130 patients diagnosed with schizophrenia or schizoaffective disorder based International Classification Diseases 10 criteria. We studied relation between development...

10.3390/jpm14080814 article EN Journal of Personalized Medicine 2024-07-31

The nature of this profession requires the development adequate defensive and coping styles. Also to have chosen for your career might mean some particularities in these areas. evaluation defense style mechanisms residents psychiatry that conduct clinical work. A descriptive study was developed determine evaluate styles psychiatry. DSQ-60 COPE scales were applied on a 31 willing resident from approximate 50 total center which conducted. most frequent found evaluated group are:...

10.1016/j.sbspro.2015.04.440 article EN Procedia - Social and Behavioral Sciences 2015-06-01

Purpose: This research article assesses the cardiovascular impact of long-term injectable antipsychotic therapy on patients diagnosed with schizophrenia spectrum disorders. In our study, we attempted to quantify potential causes damage, assess parameters, and correlate them time elapsed from onset psychosis until initiation therapy, as well duration long-acting finally, compare two most utilized (LAI) medications (olanzapine vs risperidone). Patients methods: cross-sectional study recruited...

10.2147/ndt.s186892 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2019-01-01

Introduction Toxoplasma gondii infection has been recently associated with schizophrenia and other psychiatric disorders. Aim The aim of the present study was to evaluate prevalence T. antibodies among acute patients from Western Romania. Methods This included 214 consecutive admitted at clinic, Country Clinical Emergency Hospital in Timisoara, Romania, between 30.06.2011 12.01.2012. laboratory investigations were performed these hospitalized patients, including serologic tests for IgG IgM...

10.1016/j.eurpsy.2017.01.1613 article EN European Psychiatry 2017-04-01

Caudate nucleus (CN) is a specialized part of the dorsal striatum each brain hemisphere involved in numerous cognitive processes. dysfunctions are associated with Alzheimer's, Parkinson's and Huntington's disease, autism, even schizophrenia. Most studies upon CN related diseases were conducted using neuroimaging techniques, which, some instances have reached contradictory conclusions. This state-of-the-art technique triggered development methods able to provide information at molecular...

10.1080/07328303.2019.1669632 article EN Journal of Carbohydrate Chemistry 2019-09-25

Treatment resistance requires higher doses and polypharmacy, thus increasing the risk of side effects drug interactions.The objectives study were to identify factors predicting medication choice, dose adjustments augmentation.The included patients treated with long acting injectable (LAI) antipsychotics distributed into three samples: low, middle high dosage groups (LDG/MDG/HDG).We analysed socio-demographics clinical data (age at disorder onset, total duration psychosis, pre-LAI LAI...

10.31925/farmacia.2020.1.6 article RO FARMACIA 2020-02-25

Literature shows that patients taking antipsychotic medication risk developing metabolic complications.The study aims to compare the presence of syndrome (MS) and its components in outpatients treated with long acting injectable (LAI) olanzapine risperidone.A double-center was performed on psychosis, which were divided into two samples: one another risperidone.The following data analyzed: age, gender, severity psychiatric symptoms, blood pressure, waist circumference, fasting glucose, lipid...

10.4183/aeb.2019.342 article EN Acta Endocrinologica (Bucharest) 2019-01-01

Targeting of the phenomena which arises when electric current is passing through human body leads to definition some equivalent circuits. The parameters segment skin were studied. For this, an original measuring device was conceived and built using a digital control unit based on PIC16F870 microcontroller.

10.1109/isetc.2012.6408146 article EN 2012-11-01

Pharmacogenetic markers are current targets for the personalized treatment of psychosis. Limited data exist on COMT and NRG1 polymorphisms in relation to risperidone treatment. This study focuses impact rs4680 (rs35753505, rs3924999) schizophrenia spectrum disorders (SSDs). included 103 subjects with SSD treated monotherapy. rs4680, rs35753505, rs3924999 were analyzed by RT-PCR. Participants evaluated via Positive Negative Syndrome Scale (PANSS) after six weeks. Socio-demographic clinical...

10.3390/biom14070777 article EN cc-by Biomolecules 2024-06-29

This cross-sectional analysis aimed to assess the quality of life (QoL) among hospitalized patients with alcohol use disorder (AUD) in Romania, utilizing WHOQOL survey. Conducted from January December 2023 Psychiatry Clinic "Pius Brinzeu" Emergency Clinical Hospital Timisoara, this study engaged 70 participants, adhering ethical standards outlined Declaration Helsinki. Employing WHOQOL-BREF instrument, research hypothesized that AUD would show significantly lower QoL scores across its...

10.3390/diseases12070158 article EN cc-by Diseases 2024-07-16

The manipulators, used to handling products or devices in industrial departments, needs be self-balanced order compensate the different weight of load its position workspace. known technical solution for self-balancing with counterweight, springs and actuators can substituted through a band mechanism. paper proposed new conco-balancer manipulator mechanism presents synthesis approach. non-circular profile permits variation compensated moment easy manipulated by operator.

10.4028/www.scientific.net/ssp.166-167.259 article EN Diffusion and defect data, solid state data. Part B, Solid state phenomena/Solid state phenomena 2010-09-01

The aim of this study was to develop a method for identification and quantification diazepam its major metabolite, desmethyldiazepam in plasma samples psychiatric patients. Liquid - liquid extraction (LLE) procedure applied order simplify the pre-analytical phase, followed by gas chromatography � mass spectrometry (GC-MS) detection flame ionization (GC-FID) quantitation.

10.37358/rc.17.3.5495 article EN Revista de Chimie 2017-04-15
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