Zongpei Xu

ORCID: 0000-0002-4032-7310
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About
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Research Areas
  • Traditional Chinese Medicine Studies
  • Autophagy in Disease and Therapy
  • Computational Drug Discovery Methods
  • Traditional Chinese Medicine Analysis
  • Genomics, phytochemicals, and oxidative stress
  • Cardiac electrophysiology and arrhythmias
  • Atrial Fibrillation Management and Outcomes
  • Acute Ischemic Stroke Management
  • Cardiac Arrhythmias and Treatments
  • ATP Synthase and ATPases Research
  • Plant-based Medicinal Research
  • Cardiac Fibrosis and Remodeling
  • Phytochemicals and Antioxidant Activities
  • Mitochondrial Function and Pathology
  • Skin Protection and Aging
  • Analytical Methods in Pharmaceuticals

Tianjin University of Traditional Chinese Medicine
2020-2022

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2020

Shenmai injection (SMI) has been used in the treatment of cardiovascular disease (CVD), such as heart failure, myocardial ischemia and coronary disease. It found to have efficacy on doxorubicin (DOX)-induced cardiomyopathy. The aims this study were explore underlying molecular mechanisms SMI CVD by using network pharmacology its protective effect DOX-induced cardiotoxicity vitro vivo experiment based prediction.Network method was reveal relationship between ingredient-target-disease...

10.1186/s12906-020-02905-8 article EN cc-by BMC Complementary Medicine and Therapies 2020-04-15

Myocardial remodeling represents a key factor in chronic heart failure (CHF) development, and is characterized by death of cardiomyocytes. Cardiac function changes may be attributed to inflammation, apoptosis autophagy. This study assessed the effects Qi Dan Li Xin Pill (QD) on function, inflammatory factors, autophagy cardiac CHF rats upon myocardial infarction (MI) induction. Male SD underwent sham procedure or left anterior descending coronary artery (LADCA) ligation, causing MI....

10.1038/s41598-020-63090-9 article EN cc-by Scientific Reports 2020-04-08

The aim of this study is to explore the clinical effects Chinese medicine in treatment stable angina pectoris coronary heart disease. has multitarget, multilevel, and multilink angina, which can significantly improve patients' symptoms. Its mechanism action involves multiple levels such as regulating lipid metabolism, improving platelet function, antioxidant, protecting endothelial function. design was based on data mining analyse dosing pattern modern for number episodes pectoris, duration...

10.1155/2022/3511974 article EN Journal of Healthcare Engineering 2022-02-28
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