- Academic Writing and Publishing
- Acute Ischemic Stroke Management
- Health Sciences Research and Education
- Cerebrovascular and Carotid Artery Diseases
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Innovations in Medical Education
- Cerebrovascular and genetic disorders
- Palliative Care and End-of-Life Issues
- Nursing Education, Practice, and Leadership
- Family and Patient Care in Intensive Care Units
- Nuclear Receptors and Signaling
- Conferences and Exhibitions Management
- Intracranial Aneurysms: Treatment and Complications
- Medical Coding and Health Information
- Ethics in Clinical Research
- Disability Rights and Representation
- Blood donation and transfusion practices
- Intensive Care Unit Cognitive Disorders
- Interprofessional Education and Collaboration
- Family Support in Illness
- Genetic Associations and Epidemiology
- Communication in Education and Healthcare
- Intracerebral and Subarachnoid Hemorrhage Research
- Optics and Image Analysis
University of Salford
1992-2014
Salford Royal NHS Foundation Trust
2013
University of Manchester
2002-2007
Wythenshawe Hospital
2006-2007
Manchester University
2002
To compare the occurrence of spontaneous cerebral emboli and venous to arterial circulation shunts in patients with Alzheimer's disease or vascular dementia controls without dementia.Cross sectional case-control study.Secondary care old age psychiatry services, Manchester.170 (85 disease, 85 dementia) 150 sex matched controls. Patients on anticoagulant treatment, severe dementia, marked cognitive impairment were excluded.Frequencies detection during one hour monitoring middle arteries...
The age distribution of the &#917;4 allelic form apolipoprotein E gene <i>(APOE)</i> was investigated in 630 patients with Alzheimer’s disease (AD) onset ranging from 35 to 90 years. Overall, mean at <i>APOE</i> allele bearers significantly later than that nonbearers. However, when stratified into early AD (EOAD) and late (LOAD) groups, EOAD cases bearing those without allele, whereas LOAD earlier allele. When analysed by decade, it observed 37% total number...
The aim of the study was to investigate whether possession epsilon4 allelic form apolipoprotein E (APOE) gene increases risk developing vascular dementia (VaD).APOE allele and genotype frequencies were determined by PCR in 89 patients with possible probable VaD compared those 97 Alzheimer's disease (AD) similar age onset ethnic background, 766 control subjects drawn from same geographical region.The APOE frequency all AD significantly higher (p < 0.001) than that subjects. However, also...
Genetic variations represent major risk factors for Alzheimer's disease (AD). While familial early onset AD is associated with mutations in the amyloid precursor protein and presenilin genes, only e4 allele of apolipoprotein E (APOE) gene has so far been established as a genetic factor late sporadic AD. It suggested that C-->T (224Ala-->Val) transition within exon 2 cathepsin D (CTSD) might The objective this study was to investigate whether possession CTSD T increases developing AD,...
Nowadays, the advancements of wearable consumer devices have become a predominant role in healthcare gadgets.There is always demand to obtain robust recognition heterogeneous human activities complicated IoT environments.The knowledge attained using these models will be then combined with applications.In this way, paper proposed novel deep learning framework recognize multimodal sensor data.The composed four phases: employing dataset and processing, implementation model, performance...
OBJECTIVES: To examine the association between angiotensin‐converting enzyme (ACE) deletion/insertion (D/I) polymorphism and white matter hyperintensities (WMHs) in patients with dementia. DESIGN: Observational pilot study adjustment for potential confounders using analysis of covariance. SETTING: Secondary care old‐age psychiatry services greater Manchester, United Kingdom. PARTICIPANTS: Ninety‐seven dementia: 49 Alzheimer's disease (AD, National Institute Neurological Communicative...
Abstract Background Asymptomatic spontaneous cerebral emboli (SCE) are common in dementia and associated with cognitive decline dementia. The significance of their presence older people is unknown. Method We included 96 participants (mean (SD) age 76.8 (6.7) years, 46% female) who were the control group a case‐control study to evaluate SCE Cognitive functioning was assessed prospectively over 2.5 using MMSE CAMCOG. Results mean score 28.7 (1.4) at baseline an average drop 0.79 (0.91) per...
Receiving a letter confirming acceptance for you to present poster at conference can evoke mixed emotions. Joy, panic, fear and dread are among the many possible emotions this is not exclusive first time presenters. Developing an effective presentation skill that learn provide rewarding way your work in manner less intimidating than oral (Shelledy, 2004). The key successful meticulous, timely, well informed preparation. This article outlines ten steps help guide through process maximize success.
The vascular depression hypothesis and our recent findings of increased frequency spontaneous cerebral emboli in dementia suggest that such may be involved the causation depressive symptoms dementia.To evaluate association between Alzheimer's disease dementia.In a cohort 142 patients with (72 70 dementia), clinically relevant was examined using multiple logistic regression analyses.Spontaneous were significantly more frequent (66 v. 37%, P=0.03). After adjustment for age, gender, Mini-Mental...
Delivering an oral presentation at a conference can be demanding yet exhilarating experience. It create variety of emotions such as excitement, joy and achievement--but for many the overriding are those anxiety, fear dread. A certain amount nervousness enhance your performance but how you avoid pre-presentation nerves developing into full-blown anxiety fear. The key to successful is meticulous preparation practise. This article guides through ten steps help maximize success enjoyment.
Background: Cognitive Muscular TherapyTM (CMT) is an integrated behavioural intervention developed for knee osteoarthritis.CMT teaches patients to reconceptualise the condition, integrates muscle biofeedback and aims reduce overactivity, both in response pain during daily activities.This nested qualitative study explored patient physiotherapist perspectives experiences of CMT.Methods: Five physiotherapists were trained follow a well-defined protocol then delivered CMT at least two with...
The White Paper, Equity and Excellence:liberating the NHS (DH, 2010) emphasises promotion conduct of research as a core role. updated Constitution(DH, 2013) outlines its commitment to innovation also improve current future health social care population.Furthermore, England (2013) in guidance, Everyone Counts: planning for patients 2014/15 2018/19, identified one essential elements successful sustainable economy recommending evaluation be embedded across whole patient pathway.The 6 Cs were...
Nurses spend a great deal of time and effort in constructing variety assignments dissertations as part courses, both at undergraduate postgraduate levels. It is not uncommon to read comments from lecturers such ‘this requires only minimal work be published’. might assumed that many would therefore go on appear print; however it questionable just how them ever do materialize journals. The reality this transition can challenging process. This highlighted when search the literature for use...
There is an increasing expectation that nurses, whether they work in clinical practice management, education or research, will publish. At the same time there remains a mystique about best way to go this. This article provides simple commentary suggesting ten steps help you publish professional journal.
There is an increasing importance being placed on the dissemination of research and other high quality evidence. This article first in a series three that will assist you ensuring your work presented best light at conference choice. In this we guide through ten steps need to take ensure submit possible abstract scientific committee. We also process selection.