A5102803801- Traditional Chinese Medicine Studies
- Alzheimer's disease research and treatments
- Neurological Disease Mechanisms and Treatments
- Medicinal Plants and Neuroprotection
- Cholinesterase and Neurodegenerative Diseases
- Ginkgo biloba and Cashew Applications
- Dementia and Cognitive Impairment Research
- Pharmacological Effects of Natural Compounds
- Medicinal Plants and Bioactive Compounds
- Neurological Disorders and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Complementary and Alternative Medicine Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Lipid metabolism and disorders
- Healthcare and Venom Research
- Medical Research and Treatments
- Traditional Chinese Medicine Analysis
- Neurogenesis and neuroplasticity mechanisms
- Natural product bioactivities and synthesis
- 14-3-3 protein interactions
- E-commerce and Technology Innovations
- Educational Reforms and Innovations
- Neurological diseases and metabolism
- Chronic Kidney Disease and Diabetes
- Advanced Glycation End Products research
Hebei University of Chinese Medicine
2025
First Affiliated Hospital of Hebei Medical University
2025
Affiliated Hospital of Hebei University
2024-2025
Chengdu University of Information Technology
2025
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2013-2024
Beijing University of Chinese Medicine
2003-2024
Hubei University of Chinese Medicine
2007
Hope University
2005
University of Manchester
2003-2005
Salford Royal Hospital
2005
Background The systemic immunity-inflammation index(SII) is a new indicator of composite inflammatory response. Inflammatory response an important pathological process in stroke. Therefore, this study sought to investigate the association between SII and Methods We collected data on participants with stroke from 2015–2020 cycle National Health Nutrition Examination Survey (NHANES) for cross-sectional investigation. Multivariate linear regression models were used test Fitted smoothing curves...
ABSTRACT Cerebral ischaemia–reperfusion injury (CIRI), resulting from thrombolytic therapy for ischaemic stroke, presents a considerable challenge during postoperative recovery. Formononetin (FMN) has shown promise in the prevention and treatment of neurological diseases. However, its specific mechanism ameliorating CIRI remains uncertain. Initially, we established rat model to evaluate FMN's therapeutic potential by assessing function, infarct area pathological changes. Subsequently,...
The development of automatic driving, unmanned aerial vehicle detection and virtual reality cannot be separated from the research 3D point cloud. Existing studies either lack local shape capture spatial feature description cloud, resulting in poor accuracy cloud classification network, or pursue fine complex extractors, sacrificing extraction time memory overhead to extract progress, but results show that effect is not significantly improved. Therefore, this paper proposes a Point method...
Genetic variations represent major risk factors for Alzheimer's disease (AD). While familial early onset AD is associated with mutations in the amyloid precursor protein and presenilin genes, only e4 allele of apolipoprotein E (APOE) gene has so far been established as a genetic factor late sporadic AD. It suggested that C-->T (224Ala-->Val) transition within exon 2 cathepsin D (CTSD) might The objective this study was to investigate whether possession CTSD T increases developing AD,...
Abstract Introduction This randomized, double‐blind trial aimed to test effect of a Chinese herbal medicine, Qinggongshoutao (QGST) pill, on the cognition and progression amnestic mild cognitive impairment (aMCI). Methods Patients with aMCI were randomly assigned receive QGST, Ginkgo biloba extract, or placebo for 52 weeks. The primary outcome measures possible probable Alzheimer's disease (AD) change in Disease Assessment Scale–cognitive subscale scores; secondary included assessments...
Abstract Developing a clinical practice guideline (CPG) for integrating traditional Chinese medicine (TCM) and Western (WM) requires the accurate identification, collation, integration of all available evidence on TCM WM in comprehensive, meaningful, resource‐efficient manner. This entails framing appropriate questions, retrieving synthesizing from multiple resources, providing concise complete recommendations specific diseases. However, some existing CPGs lack deep organic integration. As...
Abstract
Background . Syndromes are defined by traditional Chinese medicine as consisting of different pattern elements. Few scales have been designed for differentiating elements dementia and shown major flaws. Thus, a new element scale (PES) was developed. This study aimed to evaluate the utility PES in patients. Methods A total 171 patients were enrolled, their ascertained, first clinicians using PES, then compared with results two experts be used standard criterion independently. Reliability...
Nuclear factor erythroid 2 (NF-E2)-related (Nrf2) is a key transcription in the antioxidant response and associated with various chronic diseases. The aim of this study was to explore action esculetin, natural dihydroxy coumarin, on attenuating middle cerebral artery occlusion (MCAO) reperfusion, whether its effect dependent Nrf2 activation, as well nuclear factor-kappa B (NF-κB) inhibition. Two doses esculetin (20 40 mg/kg) were tested rats MCAO reperfusion. Neurological deficiency,...
GEPT capsule is a patent prescription developed by our team. This combination of five active components extracted from herbs widely studied for its potential effects on memory and cognition in laboratories. To date, adequately powered clinical trials testing the effect mild cognitive impairment are lacking. The aim reported trial was to investigate efficacy amnestic (aMCI). 24 week, double-blind, parallel, randomized controlled capsules 7.5g daily versus donepezil 5mg daily, which conducted...