A5100343497- Vascular Procedures and Complications
- Advanced Breast Cancer Therapies
- Lung Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Gallbladder and Bile Duct Disorders
- Biliary and Gastrointestinal Fistulas
- Gastric Cancer Management and Outcomes
- Radiation Dose and Imaging
- Cardiac tumors and thrombi
- Pulmonary Hypertension Research and Treatments
- CAR-T cell therapy research
- Cerebrovascular and Carotid Artery Diseases
- Pediatric Hepatobiliary Diseases and Treatments
- Orthopaedic implants and arthroplasty
- Metastasis and carcinoma case studies
- Cancer Treatment and Pharmacology
- Coronary Interventions and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Treatments and Studies
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Immunotherapy and Immune Responses
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Congenital Diaphragmatic Hernia Studies
The Seventh Affiliated Hospital of Sun Yat-sen University
2025
Sun Yat-sen University
2025
Anshan Hospital
2022-2023
First Affiliated Hospital of Nanchang University
2022
Nanchang University
2022
Capital Medical University
2022
Hainan Branch of People's Liberation Army General Hospital
2019
Chinese People's Liberation Army
2019
Peking University Third Hospital
2018
Peking University
2018
Multiple studies have demonstrated that the abundance and functionality of γδ T cells are favorable prognostic indicators for prolonged survival in cancer patients. However, association between immunophenotype circulating therapeutic response NSCLC patients undergoing chemotherapy or targeted therapy remains unclear. Patients with EGFR wild-type (EGFR-WT) mutant (EGFR-Mut) non-small cell lung (NSCLC), diagnosed January 2020 2024, were included this study. Clinicopathological characteristics,...
Current therapies for HER2-positive breast cancer have limited efficacy in patients with triple-positive (TPBC). We conduct a multi-center single-arm phase 2 trial to test the and safety of an oral neoadjuvant therapy pyrotinib, letrozole dalpiciclib (a CDK4/6 inhibitor) treatment-naïve, stage II-III TPBC Karnofsky score ≥70 (NCT04486911). The primary endpoint is proportion pathological complete response (pCR) axilla. secondary endpoints include residual burden (RCB)-0 or RCB-I, objective...
128 Background: Advanced gastric cancer (AGC) is a major problem particularly in Asian countries. The treatment options are limited after standard first line chemotherapy. This phase I/II study aimed to evaluate the tolerability, pharmacokinetics and preliminary efficacy of fruquintinib, selective oral VEGFR inhibitor, combined with paclitaxel as second-line therapy Chinese patients AGC. Methods: open arm trial (NCT02415023) consisted dose finding expansion stages. In stage, 3 levels...
The feasibility and clinical application of single-hole video-assisted thoracoscope in pulmonary peripheral tumors was examined. From March, 2011 to 2015, we retrospectively analyzed the data obtained from 32 patients with tumor that received thoracoscopic surgery. We completed surgery via a 1.5-cm incision on seventh or eighth rib midaxillary line as observation hole, 4.0-5.0-cm lateral margin pectoralis major fourth fifth operation hole. All had tumor-reductive under successfully. None...
To compare patency between suspended over length biliary stents (SOBSs; made from nasobiliary tube) and conventional plastic (CPBSs).We retrospectively analyzed 61 patients with extrahepatic stricture who underwent SOBS placement (intrahepatic bile duct) 74 CPBS placement. Stent complications were compared.The group was slightly older contained more females than the but other baseline characteristics similar. Malignant obstruction accounted for 57.4% (SOBS group) 45.9% (CPBS of cases....
In order to analyze the feasibility of pulmonary lobectomy for non-small cell lung cancer (NSCLC) in early period after percutaneous coronary intervention (PCI), current study was designed compare perioperative characteristics and prognostic performance patients with within 3 months or later PCI.This enrolled 349 simultaneously NSCLC stenosis. There were 198 151 PCI, respectively.Age all 62 [53-75] years. no difference demographic characteristics, medical histories, locations stent numbers...
e12603 Background: Our previous MUKDEN 01 study showed a promising total pathological complete response (tpCR) rate of 30.4% with neoadjuvant pyrotinib plus dalpiciclib (cyclin dependent kinase 4/6 inhibitor) and letrozole in patients triple-positive breast cancer (TPBC), but the efficacy still needs improvement. This pilot explored safety adding trastuzumab to this regimen TPBC. Methods: Patients received five 28-day cycles (320 mg once daily), (125 daily on days 1-21) (2.5 six 21-day (8...
588 Background: Despite the use of multiple lines targeted therapy has revolutionized treatment for HER2-positive breast cancer, these methods still have limited efficacy triple-positive cancer (TPBC), which calls persistent exploration optimized strategy. This MUKDEN-01 prospective trial aimed to evaluate oral, chemo-sparing neoadjuvant with pyrotinib, letrozole and dalpiciclib, also meet need convenience under COVID-19 pandemic, patients TPBC. Methods: The MUKDEN 01 was an...
Distal transradial approach (dTRA) is safe and effective for coronary angiography PCI. However, its impact on radiation exposure in the catheterization laboratory has not been characterized. We performed a systematic review meta-analysis of scientific literature by searching PubMed, Embase, Cochrane Library databases with relevant terms until October 13, 2022. Randomized controlled trials (RCTs) comparing dTRA traditional radial (TRA) were selected. The primary outcome was (fluoroscopy time,...
Background: In order to analyze the feasibility of pulmonary lobectomy for non-small cell lung cancer (NSCLC) in early period after percutaneous coronary intervention (PCI), current study was designed compare perioperative characteristics and prognostic performance patients with within 3 months or later PCI. Methods: This enrolled 349 simultaneously NSCLC stenosis. There were 198 151 PCI, respectively. Results: Age all 62 [53–75] years. no difference demographic characteristics, medical...