A5041186798- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Politics and Conflicts in Afghanistan, Pakistan, and Middle East
- Indian Economic and Social Development
- Genomics and Phylogenetic Studies
- Protein Structure and Dynamics
- South Asian Studies and Conflicts
- Enzyme Structure and Function
- International Relations and Foreign Policy
- RNA and protein synthesis mechanisms
- Gene expression and cancer classification
- Global Financial Crisis and Policies
- Global Peace and Security Dynamics
- Advanced Graph Theory Research
- International Development and Aid
- Asian Geopolitics and Ethnography
- Machine Learning in Bioinformatics
- Insect symbiosis and bacterial influences
- Microbial Community Ecology and Physiology
- Nuclear Issues and Defense
- Algorithms and Data Compression
- Genetic Associations and Epidemiology
- Bioinformatics and Genomic Networks
- Forensic Entomology and Diptera Studies
- Plant Pathogens and Fungal Diseases
Asian Institute of Medical Sciences
2023
Rajasthan Dental College and Hospital
2022
Research & Development Establishment (Engrs.)
2020
Defence Research and Development Establishment
2020
North-West University
2015-2018
Indian Institute of Technology Ropar
2014-2017
Inter-University Centre for Astronomy and Astrophysics
2017
Central Council for Research in Ayurvedic Science
2017
Dr. Yashwant Singh Parmar University of Horticulture and Forestry
2016
University of British Columbia
2010-2015
House flies (Musca domestica L.) are cosmopolitan, ubiquitous, synanthropic insects that serve as mechanical or biological vectors for various microorganisms. To fully assess the role of house in epidemiology human diseases, it is essential to understand diversity microbiota harbored by natural fly populations. This study aimed identify gut bacteria both culture-dependent and culture-independent approaches. A total 102 bacterial strains were isolated from 65 collected public places including...
Abstract Background Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral particular has proven to be a powerful tool amenable applications. However, it cannot directly applied due time and memory limitations. To address this issue, we modified spectral by adding an information preserving sampling procedure applying post-processing stage. We call entire algorithm SamSPECTRAL. Results tested our on flow...
Monoubiquitination of H2BK123 (H2BK123ub), catalyzed by Rad6/Bre1, is a transient histone modification with roles in transcription and essential for establishing H3K4 H3K79 trimethylations (H3K4me3 H3K79me3). Here, we investigated the chromatin network around H2BK123ub examining its localization co-occurrence dependent marks as well elongation mark H3K36me3 across genome Saccharomyces cerevisiae. In yeast, removed deubiquitinases Ubp8 Ubp10, but their genomic target regions remain to be...
Complex intracellular signaling networks monitor diverse environmental inputs to evoke appropriate and coordinated effector responses. Defective signal transduction underlies many pathologies, including cancer, diabetes, autoimmunity about 400 other human diseases. Therefore, there is high impetus define the composition architecture of cellular communications in humans. The major components are protein kinases phosphatases, which catalyze reversible phosphorylation proteins. Here, we have...
Two Gram-negative-staining, aerobic, non-motile, rod-shaped bacteria, designated strains FFA1 T and FFA3 , belonging to the class Gammaproteobacteria were isolated from gastrointestinal tract of adult flesh flies (Diptera: Sarcophagidae). Phylogenetic analysis 16S rRNA gene sequence data placed these two within genus Ignatzschineria with similarities 98.6 % (FFA1 ) 99.35 (FFA3 larvae L1/68 . The level similarity between was 99 %, 97.15 78.1 based on rRNA, 23S gyrB sequences, respectively....
Abstract Flesh flies of the genus Sarcophaga (Diptera: Sarcophagidae) are carrion‐breeding, necrophagous insects important in medical and veterinary entomology as potential transmitters pathogens to humans animals. Our aim was analyse diversity gut‐associated bacteria wild‐caught larvae adult flesh using culture‐dependent culture‐independent methods. Analysis 16S rRNA gene sequences from cultured isolates clone libraries revealed affiliated Proteobacteria, Actinobacteria, Firmicutes...
If the immune system is an interconnected network, then evolution of archetype that ideal for fighting one pathogen should result in tradeoffs decreasing its ability to fight others. How many archetypes are there system? We infected diverse mice with Plasmodium chabaudi, and identified five distinct responses based on host's position microbial load, activity, host damage space. To better understand nature these archetypes, we developed a mathematical model generalized host-pathogen system....
We have explored a novel turn-on fluorescence detection of sulfur mustard (SM) at "room temperature". The innovative protocol that uses the combination luminol and an ionic liquid in water exhibits SM within seconds. In this simple, fast, low-cost chemosensing method, acts as receptor well signaling element, (1-ethyl-3-methylimidazolium dicyanamide) provides requisite polarizing medium to realize Interestingly, with higher concentration probe (0.56 mM), sensing can be visualized naked eye,...
One challenge in applying bioinformatic tools to clinical or biological data is high number of features that might be provided the learning algorithm without any prior knowledge on which ones should used. In such applications, can drastically exceed training instances often limited by available samples for study. The Lasso one many regularization methods have been developed prevent overfitting and improve prediction performance high-dimensional settings. this paper, we propose a novel...
We have analyzed 7,137 samples from 125 different caste, tribal and religious groups of India 99 three populations Nepal for the length variation in COII/tRNA<sup>Lys</sup> region mtDNA. Samples showing were subjected to detailed phylogenetic analysis based on HVS-I informative coding sequence variation. The overall frequencies 9-bp deletion insertion variants South Asia 1.9 0.6%, respectively. also defined a novel deep-rooting haplogroup M43 identified rare H14 Indian carrying...
Coronavirus disease 2019 (COVID-19) infection in India demonstrated three peaks India, with differences presentation and outcome all the waves. The aim of paper was to assess epidemiological, clinical features outcomes patients COVID-19 presenting at a tertiary care hospital waves Jaipur, India.This retrospective study conducted India. Demographic, were compared confirmed cases admitted during first wave (16-7-2020 31-1-2021), second (16-3-2021 6-5-2021) third (1-1-22 20-2-22) outbreak.There...
A Gram-negative, facultatively anaerobic, rod-shaped, catalase- and oxidase-positive bacterium, motile by means of a single polar flagellum designated strain KJW27(T), was isolated from the marine sediment Karwar jetty, west coast India. The β-haemolytic grew with 0-10 % (w/v) NaCl, at 10-45 °C pH 6.5-10, optimum growth 2 37 7.5. major fatty acids were iso-C₁₅:₀ (22.2 %), C₁₇:₁ω8c (21 summed feature 3 (comprising C₁₆:₁ω7c and/or C₁₆:₁ω6c; 10.2 C₁₆:₀ (7.1 iso-C₁₃:₀ (5.6 %) C₁₇:₀ (4.4 %). DNA...
Vehicle detection has been the critical part of traffic surveillance system for many years. However, vehicle method is still challenging. In this paper, differential morphology closing profile used to extract automatically from image. Along with profile, some addition operation applied as a algorithm get high and quality rate. Result demonstrated that novel an excellent percentage. We also have compared our automated other traditional image processing based methods results indicate proposed...
Abstract The article argues that India does not have a well-defined neighbourhood policy. It makes historical survey of the approaches different Indian leaders to and examines reasons for prevailing negative perceptions about in region. these come because has largely adopted an ad hoc bilateral approach vis-à-vis its neighbours allowed policy be guided by overarching concern security. In recent years, India's changed considerably. However, it needs clearer articulation. suggests must...
We have carried out a polyphasic taxonomic characterization of Bacillus beijingensis DSM 19037(T) and ginsengi 19038(T), which are closely related phylogenetically to Bhargavaea cecembensis LMG 24411(T). All three strains Gram-stain-positive, non-motile, moderately halotolerant non-spore-forming. 16S rRNA gene sequence analyses showed that the constituted coherent cluster, with similarities between 99.7 98.7 %. The percentage similarity on basis amino acid sequences deduced from partial gyrB...
The inverse protein folding problem is that of designing an amino acid sequence which has a particular native fold. This arises in drug design where structure necessary to ensure proper protein-protein interactions. In this paper, we show the 2D HP model Dill it possible solve for broad class structures. These structures can be used closely approximate any given structure. One most important properties good (in design) its stability--the aptitude not fold simultaneously into other We number...
A global temperature rise is being experienced earliest and most intensely in the Arctic region. The changes are worrying but commercial interests equally enticing. witnessing convergence of geophysical, geo-economic geostrategic strange dramatic ways, making it a paradox an antithesis. For India, distant when comes to economic near climate change. As India today reassesses rethinks its role new geopolitical space, becomes important part that reorientation movement towards 'global knowledge...
The Arctic Ocean is melting at an alarming pace. In 2005, the extent of summer-time ice in was lowest last 50 years, and 2007, it 38 per cent lower than average sin...