A5107338544- Transcranial Magnetic Stimulation Studies
- Vestibular and auditory disorders
- Functional Brain Connectivity Studies
- Pain Management and Treatment
- Neurological disorders and treatments
- Motor Control and Adaptation
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Treatment of Major Depression
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury Research
- Muscle activation and electromyography studies
- Stroke Rehabilitation and Recovery
- Spatial Neglect and Hemispheric Dysfunction
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Neuroscience and Neural Engineering
- Sport Psychology and Performance
- Traumatic Brain Injury and Neurovascular Disturbances
- Sleep and Wakefulness Research
- Attention Deficit Hyperactivity Disorder
- Spinal Cord Injury Research
- Psychosomatic Disorders and Their Treatments
- Action Observation and Synchronization
- Conducting polymers and applications
University of Ottawa
2019-2024
Royal Ottawa Mental Health Centre
2019-2024
Université du Québec en Outaouais
2021-2024
Carleton University
2019-2024
University College London
2016-2020
National Hospital for Neurology and Neurosurgery
2016-2020
Sobell House
2016-2019
Centre for Addiction and Mental Health
2019
University of Toronto
2019
Douglas Mental Health University Institute
2017
To perform strictly unilateral movements, the brain relies on a large cortical and subcortical network. This network enables healthy adults to complex unimanual motor tasks without activation of contralateral muscles. However, mirror movements (involuntary in ipsilateral muscles that can accompany intended movement) be seen individuals if task is or fatiguing, childhood, with increasing age. Lateralization movement depends interhemispheric communication between (i.e., dorsal premotor cortex,...
Transcranial magnetic stimulation (TMS) can provide an index of intracortical excitability/inhibition balance. However, the neurochemical substrate these measures remains unclear. Pharmacological studies suggest involvement GABA A and B receptors in TMS protocols aimed at measuring inhibition, but this link inferential. Proton resonance spectroscopy ( 1 H-MRS) permits measurement glutamate + glutamine (Glx) concentrations human brain might help direct empirical assessment relationship...
Changes in neural activity occur the motor cortex before movement, but nature and purpose of this preparatory is unclear. To investigate human (male female) brain noninvasively, we used transcranial magnetic stimulation (TMS) to probe excitability distinct sets excitatory inputs corticospinal neurons during warning period various reaction time tasks. Using two separate methods (H-reflex conditioning directional effects TMS), show that a specific set are suppressed preparation, while another...
Abstract Since the initial demonstration of linear effects stimulation duration and intensity on strength after‐effects associated with transcranial direct current ( tDCS ), few studies have systematically assessed how varying these parameters modulates corticospinal excitability. Therefore, objective this study was to evaluate anodal excitability at two intensities (1 mA, 2 mA) durations (10 min, 20 min), determine value several variables in predicting response. Two groups individuals...
Activity of the primary motor cortex (M1) during action observation is thought to reflect resonance. Here, we conducted three studies using transcranial magnetic stimulation (TMS)-induced motor-evoked potentials (MEPs) first dorsal interosseus muscle (FDI) determine: (i) time course M1 corticospinal excitability a simple finger movement; (ii) specificity modulation in terms type movement and muscle; (iii) relationship between activity measures empathy autistic traits. In study, administered...
It is known that transcranial direct current stimulation (tDCS) can induce polarity-specific shifts in brain excitability of the primary motor cortex (M1) with anodal tDCS enhancing and cathodal reducing cortical excitability. However, less about its impact on specific intracortical inhibitory mechanisms, such as γ-aminobutyric acid B (GABAB)-mediated inhibition. Consequently, aim present study was to assess M1 inhibition healthy individuals. Long-interval (LICI) silent period (CSP)...
Using concurrent transcranial magnetic stimulation (TMS) and electroencephalography (TMS-EEG), this study aims to compare the effect of three intermittent theta-burst (iTBS) doses on cortical activity in left dorsolateral prefrontal (DLPFC) cortex.Fourteen neurotypical participants took part following experimental conditions: 600, 1200 1800 pulses. TMS-EEG recordings were conducted DLPFC pre/post iTBS, including single-pulse TMS short- long-interval intracortical inhibition (SICI, LICI)....
Studies using transcranial magnetic stimulation (TMS) have demonstrated the importance of direction and intensity applied current when primary motor cortex (M1) is targeted. By varying these, it possible to stimulate different subsets neural elements, as by modulation evoked potentials (MEPs) behaviour. The latter involves premotor areas well, among them, presupplementary area (pre–SMA) has recently received significant attention in study inhibition. It that, similar M1, neuronal populations...
OPINION article Front. Neural Circuits, 29 November 2016 Volume 10 - | https://doi.org/10.3389/fncir.2016.00097
Application of transcranial alternating current stimulation (tACS) is thought to modulate ongoing brain oscillations in a frequency-dependent manner. However, recent studies report various and sometimes inconsistent results regarding its capacity induce changes cortical activity beyond the period. Here, thirty healthy volunteers participated randomized, cross-over, sham-controlled, double-blind study using EEG measure offline effects tACS on alpha beta power. Sham high density (1 mA; 10 Hz...
Transcranial direct current stimulation (tDCS) is a neuromodulation technique that has been increasingly used over the past decade in treatment of neurological and psychiatric disorders such as stroke depression. Yet, mechanisms underlying its ability to modulate brain excitability improve clinical symptoms remains poorly understood 33. To help this understanding, proton magnetic resonance spectroscopy (1H-MRS) can be it allows vivo quantification metabolites γ-aminobutyric acid (GABA)...
BackgroundPolarising currents can modulate membrane potentials in animals, affecting the after-effect of theta burst stimulation (TBS) on synaptic strength.ObjectiveWe examined whether a similar phenomenon could also be observed human motor cortex (M1) using transcranial direct current (TDCS) during monophasic intermittent TBS (iTBS).MethodsTDCS was applied posterior-anterior iTBS three different conditions: TDCS (anode 3.5 cm posterior to M1, cathode anterior M1), anterior-posterior...
Purpose: The aim of the present study was to assess, in healthy individuals, impact M1-M1 tDCS on primary motor cortex excitability using transcranial magnetic stimulation and sensorimotor metabolite concentration 1H-MRS. Methods: For both experiments, each participant received thr ee following interventions (20 min tDCS, 1 mA): left-anodal/right-cathodal, left-cathodal/right-anodal, sham. effects were assessed via evoked potentials (experiment 1) concentrations 2) immediately after 12...