A5079598950- Transcranial Magnetic Stimulation Studies
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Advanced MRI Techniques and Applications
- Muscle activation and electromyography studies
- Advanced Neuroimaging Techniques and Applications
- Neurological disorders and treatments
- Neurobiology of Language and Bilingualism
- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Spinal Cord Injury Research
- Stroke Rehabilitation and Recovery
- Vestibular and auditory disorders
- Phonetics and Phonology Research
- Neuroscience and Neural Engineering
- Intraoperative Neuromonitoring and Anesthetic Effects
- Hemispheric Asymmetry in Neuroscience
- Traumatic Brain Injury Research
- Visual perception and processing mechanisms
- Pain Management and Treatment
- Photoreceptor and optogenetics research
- Voice and Speech Disorders
- Meningioma and schwannoma management
- Attention Deficit Hyperactivity Disorder
- Epilepsy research and treatment
Aalto University
2019-2025
University of Helsinki
2013-2025
Helsinki University Hospital
2014-2025
Weizmann Institute of Science
2023
University of Padua
2022
Centre for Addiction and Mental Health
2018-2021
Imaging Center
2008-2021
University of Toronto
2018-2019
Hospital District of Helsinki and Uusimaa
2008-2013
Finnish Brain Research and Rehabilitation Center Neuron
2007-2008
Abstract Navigated transcranial magnetic stimulation combined with electroencephalography (nTMS‐EEG), allows noninvasive studies of cortical excitability and connectivity in humans. We investigated the reproducibility nTMS‐EEG seven healthy subjects by repeating left motor prefrontal a 1‐week interval. TMS was applied at three intensities: 90, 100, 110% subjects' threshold (MT). The TMS‐compatible neuronavigation system guaranteed precise repositioning coil. responses were recorded...
BACKGROUND: Navigated transcranial magnetic stimulation (nTMS) is increasingly used in presurgical brain mapping. Preoperative nTMS results correlate well with direct cortical (DCS) data the identification of primary motor cortex. Repetitive can also be for mapping speech-sensitive areas. OBJECTIVE: The current cohort study compares safety and effectiveness preoperative DCS during awake surgery language areas patients left-sided cerebral lesions. METHODS: Twenty tumors or close to eloquent...
Transcranial magnetic stimulation (TMS) is widely used in brain research and treatment of various dysfunctions. However, the optimal way to target administer TMS therapies, for example, where which electric field direction stimuli should be given, yet determined.To develop an automated closed-loop system adjusting parameters (in this work, stimulus orientation) online based on TMS-evoked activity measured with electroencephalography (EEG).We developed TMS-EEG set-up. In set-up, are...
Translational network neuroscience aims to integrate advanced neuroimaging and data analysis techniques into clinical practice better understand treat neurological disorders. Despite the promise of technologies such as functional MRI diffusion combined with tools, field faces several challenges that hinder its swift translation. We have identified nine key roadblocks impede this process: (a) theoretical basic science foundations; (b) construction, interpretation, validation; (c) access,...
Neuromodulation is based on the principle that brain stimulation produces plastic changes in cerebral circuitry. Given intersubject structural and functional variability, neuromodulation has a personalized effect brain. Moreover, because of dominance interhemispheric differences same individual, characterization specific circuitries involved currently not feasible. This notion extremely important for treatments applied neuropsychiatry. Specifically, efficacy critically dependent anatomical...
Hyperactivity in the subgenual cingulate cortex (SGC) is associated with major depressive disorder (MDD) and anticorrelated activity dorsolateral prefrontal (DLPFC). This association was found to be predictive of responsiveness repetitive transcranial magnetic stimulation (rTMS) treatment. Such findings suggest that DLPFC-SGC connectivity important for understanding both therapeutic mechanism rTMS patients MDD underlying pathophysiology MDD.To evaluate SGC hyperactivity before after...
Transcranial magnetic stimulation (TMS) has been used to induce speech disturbances and affect performance during different naming tasks. Lately, repetitive navigated TMS (nTMS) for non-invasive mapping of cortical speech-related areas. Different tasks may give information that can be useful presurgical evaluation. We studied the sensitivity object action nTMS compared distributions sites where produced errors. Eight healthy subjects named pictures objects actions delivered semi-random...
New neuromodulation technologies, such as transcranial magnetic stimulation (TMS), are promising tools for neurorehabilitation, aphasia therapy included. Combined with behavioral techniques, in particular treatment-efficient Intensive Language-Action Therapy (ILAT, previously CIAT or CILT), TMS could substantially amplify the beneficial effect of alone (Thiel et al., 2013; Martin 2014; Mendoza 2016; Kapoor, 2017). In this randomized study 17 subjects post-stroke chronic stage, we studied...
Using concurrent transcranial magnetic stimulation (TMS) and electroencephalography (TMS-EEG), this study aims to compare the effect of three intermittent theta-burst (iTBS) doses on cortical activity in left dorsolateral prefrontal (DLPFC) cortex.Fourteen neurotypical participants took part following experimental conditions: 600, 1200 1800 pulses. TMS-EEG recordings were conducted DLPFC pre/post iTBS, including single-pulse TMS short- long-interval intracortical inhibition (SICI, LICI)....
A large proportion of spinal cord injuries (SCI) are incomplete. Even in clinically complete injuries, silent non-functional connections can be present. Therapeutic approaches that strengthen transmission weak neural to improve motor performance needed. Our aim was determine whether long-term delivery paired associative stimulation (PAS, a combination transcranial magnetic [TMS] with peripheral nerve [PNS]) enhance output the hands patients chronic traumatic tetraplegia, and compare this...
Central poststroke pain (CPSP), a neuropathic condition, is difficult to treat. Repetitive transcranial magnetic stimulation (rTMS) targeted the primary motor cortex (M1) can alleviate but not all patients respond. We aimed assess promising alternative rTMS target, secondary somatosensory (S2), for CPSP treatment.This prospective, randomized, double-blind, Sham-controlled three-arm crossover trial assessed navigated (nrTMS) M1 and S2 (10 sessions, 5050 pulses per session at 10 Hz)....
Background: The combination of transcranial magnetic stimulation (TMS) with electroencephalography (EEG) allows for non-invasive investigation cortical response and connectivity in human cortex. This study aimed to examine the amplitudes latencies each TMS-evoked potential (TEP) component induced by single-pulse TMS (spTMS) left motor (M1) dorsolateral prefrontal cortex (DLPFC) among healthy young participants (YNG), older (OLD), patients schizophrenia (SCZ). Methods: We compared...
Transcranial magnetic stimulation (TMS) stimulates the brain by electromagnetic induction. The outcome depends on multiple parameters such as induced electric-field pattern (in particular, location of peak field and its orientation), intensity timing. However, it is not clear how TMS-evoked responses are affected all parameters. This study elucidates dependency electroencephalography (EEG) orientation stimulating electric field. To achieve this, we analysed a dataset from six subjects who...