- Health and Lifestyle Studies
- Obesity, Physical Activity, Diet
- Clinical Nutrition and Gastroenterology
- Child Nutrition and Water Access
- Nutrition and Health in Aging
- Genetics and Neurodevelopmental Disorders
- Child Nutrition and Feeding Issues
- Carcinogens and Genotoxicity Assessment
- Cerebral Palsy and Movement Disorders
- Sepsis Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Curcumin's Biomedical Applications
- Nutritional Studies and Diet
- Infant Nutrition and Health
- Liver Disease Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Neonatal and Maternal Infections
- Heart Rate Variability and Autonomic Control
- Hemophilia Treatment and Research
- Parkinson's Disease Mechanisms and Treatments
- Hepatitis C virus research
- Voice and Speech Disorders
- Toxoplasma gondii Research Studies
- Childhood Cancer Survivors' Quality of Life
- Global Public Health Policies and Epidemiology
Universidad de Guadalajara
2009-2019
Centro de Epilepsia y Neurocirugía Funcional
2014
Hospital Civil de Guadalajara
2011
Abstract Background Cervical cancer is the second most common in women worldwide. NK and cytotoxic T cells play an important role elimination of virus-infected tumor through NKG2D activating receptors, which can promote lysis target by binding to major histocompatibility complex class I-related chain A (MICA) proteins. Increased serum levels MICA have been found patients with epithelial tumors. The aim this study was compare soluble (sMICA) NKG2D-expressing blood samples from cervical or...
Objective . To evaluate the effects of ezetimibe/simvastatin (EZE/SIMV) and rosuvastatin (ROSUV) on oxidative stress (OS) markers in patients with diabetic polyneuropathy (DPN). Methods We performed a randomized, double-blind, placebo-controlled phase III clinical trial adult Type 2 Diabetes Mellitus (T2DM) DPN, as evaluated by composite scores nerve conduction studies (NCS). Seventy-four subjects T2DM were allocated 1 : to placebo, EZE/SIMV 10/20 mg, or ROSUV 20 mg for 16 weeks. All...
Diabetic neuropathy affects 50%-66% of patients with diabetes mellitus. Oxidative stress generates nerve dysfunction by causing segmental demyelinization and axonal degeneration. Antioxidants are considered to be the only etiologic management for diabetic polyneuropathy, statins such as rosuvastatin increase nitric oxide bioavailability reduce lipid peroxidation. The aim this study was evaluate antioxidant effect in polyneuropathy.We conducted a randomized, double-blind, placebo-controlled...
ABSTRACT Objectives: To compare the anthropometric indicators based on weight and height with arm measurements to predict nutritional status liver function tests (LFTs) in children chronic disease (CLD). Patients Methods: A cross‐sectional study a referral pediatric hospital enrolled 79 CLD (mean age 72.6 ± 61.8 months, 54% female). An independent variable of LFT was used determine outcome status. Anthropometric versus age, height, head circumference were analyzed Pearson correlation,...
Hemophilia A (HA) is one of the most common inherited bleeding disorders caused by FVIII gene mutations. Inversion intron 22 (inv22) originates 50% cases severe HA and a major risk factor for inhibitor development. 1 (inv1) has been reported to occur in 2-3% patients. We studied both inversions determine their frequencies Mexican patients with compare these data other populations. The inv22 was evaluated as development 44 from 31 families detection 94 65 detect inv1. used subcycling...
Abstract Lung cancer is a malignant disease with increasing mortality rates. Cytokines play role in normal cell growth regulation and differentiation are also implicated disease. Among these cytokines, Transforming Growth Factor β type 1 (TGF‐β1) acts as tumor promoter cells. Several clinical studies have found high levels of TGF‐β1 various types. The aim this study was to establish cut‐off point complementary diagnostic tool lung detection. Therefore, 72 clinically well‐characterized...
To demonstrate that a nutritional support intervention, via naso-enteral tube-feeding or gastrostomy, has significant impact on the status and body composition in severely malnourished children with cerebral palsy spastic quadriplegia.Thirteen patients moderate/severe malnutrition quadriplegia who were fed gastrostomy included cohort study. Anthropometric measurements estimated by bioelectric impedance analysis obtained. ANOVA Wilcoxon tests used.During four weeks of recovery, an average...
Procalcitonin and C-reactive-protein are inflammatory markers for sepsis. The authors evaluated their sensitivity specificity in pediatric patients with cancer febrile neutropenia.Serum procalcitonin were evaluated. Patients (n = 54) divided into 2 groups, severe infection 18) or without documented 36).Procalcitonin C-reactive protein significantly higher the high-risk group. displayed 72.2% 80.5% specificity. had a of 77.7% 77.2%.Procalcitonin is an accurate predictor bacterial neutropenic...
The aim of this work was to establish a potential correlation between specific polymorphisms and presence hepatic fibrosis in Mexican patients with established liver (ELF). Second, necroinflammatory index improvement correlated Pirfenidone (PFD) treatment response the same polymorphisms.We analyzed TGF-beta codon 25, single basepair guanine insertion-deletion polymorphism (4G/5G) for PAI-1 angiotensin AT-6 nucleotide located -6 promoter region. Twenty infected either hepatitis C virus (HCV)...
To analyze the total energy expenditure (TEE) and resting (REE) in children with cerebral palsy (CP) moderate or severe malnutrition during nutritional recovery. In an intervention study, thirteen subjects CP (10 females 3 males a mean age of 9y11m ± 2y3m), level V Gross Motor Function Classification System were included. Eight fed by nasogastric tube five gastrostomy. They compared 57 healthy participants (31 26 8y7m 10m). Anthropometric measurements, body composition bioelectrical...
CYP1A1 is a gene involved in the high aryl hydrocarbon hydroxylase -inducible phenotype, which genetically-determined variation among individuals that has been associated with lung cancer risk. More specifically, *2B and *4 polymorphisms have susceptibility to cigarette smokers.DNA was obtained from blood samples we studied by PCR-RFLP distribution of (n=248) (n=222) healthy controls 222 patients Mexican population.Comparisons between groups showed an increased risk for *2B/*2B (18%; OR 7.6;...
Background/Aim The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) TGFB1 (rs1800471), AT (rs3789679), MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) histological grading necroinflammation, staging hepatic fibrosis, liver function in Mexican patients with advanced fibrosis due chronic hepatitis C virus infection. Methods AT, MMP-1, MMP-3, gene were analyzed by polymerase chain reaction real time, whereas polymorphism detected...