A5101656371- interferon and immune responses
- Cytokine Signaling Pathways and Interactions
- Immune Cell Function and Interaction
- Health and Wellbeing Research
- Healthcare and Venom Research
- Immune cells in cancer
- Dental Health and Care Utilization
- Pectus Deformity Diagnosis and Treatment
- Medical Research and Treatments
- Head and Neck Anomalies
- Ocular Diseases and Behçet’s Syndrome
- Facial Nerve Paralysis Treatment and Research
- Diverse Approaches in Healthcare and Education Studies
- Nutrition, Health and Food Behavior
- Healthcare Education and Workforce Issues
- Leprosy Research and Treatment
- Multiple and Secondary Primary Cancers
- Acupuncture Treatment Research Studies
- Hepatitis Viruses Studies and Epidemiology
- Ergonomics and Musculoskeletal Disorders
- NF-κB Signaling Pathways
- Patient Dignity and Privacy
- Heparin-Induced Thrombocytopenia and Thrombosis
- Lymphoma Diagnosis and Treatment
- Cancer-related Molecular Pathways
GL PharmTech (South Korea)
2024
Kyungpook National University Hospital
2018
Jeonbuk National University
2011-2017
Catholic University of Korea
2015
Seoul National University
2011
Chungnam National University
2009
Dankook University Hospital
2006
Relatively little is known about thrombotic adverse events (AEs) of emicizumab in postmarketing real-world settings, particularly comparison with factor VIII (FVIII) products. A recent European study reported a potentially greater risk compared FVIII
Allogeneic natural killer (NK) cell therapy is a potential therapeutic approach for variety of solid tumors.We established an expansion method large-scale production highly purified and functionally active NK cells, as well freezing medium the expanded cells.In present study, we assessed effect cryopreservation on cells in regards to viability, phenotype, anti-tumor activity.NK were enormously (about 15,000-fold expansion) with high viability purity by stimulating CD3 + T cell-depleted...
The cell-cycle regulator Cks1 has recently been implicated in Skp2-mediated ubiquitination of the tumor suppressor protein p27. In this article, we report that exerts a Skp2-independent regulation NF-κB promotes interleukin-8 (IL-8) expression, which is critical to hepatocellular carcinoma (HCC) growth. was upregulated frequently human HCC tissues and cell lines. knockdown cells elevated p27 levels decreased tumorigenicity manner also associated with strong downregulation IL-8 expression....
Activation of cell surface CD30 by immobilized anti-CD30 monoclonal antibodies (mAb) induces strong apoptosis in human eosinophils. This mAb-induced eosinophil is inhibited the addition inhibitors p38, ERK1/2 mitogen-activated protein kinases, and phosphatidylinositol 3-kinase. However, there little data investigating role Bcl-2 caspases induced mAb. We sought to determine whether mAb via caspase pathways.Peripheral blood was drawn from 37 healthy volunteers. The expression on eosinophils...
본 연구는 중학생을 대상으로 학생들의 주관적인 구강건강상태에 따라 구강건강증진행위에 어떠한 영향을 미치는지를 조사하여 향후 청소년의 구강건강프로그램 개발에 기초자료로 사용하고자 2011년 3월 7일부터 2주간 중학생 1,100을 연구를 실시하였다. 먼저 주관적 대해 살펴보면 학년에 따라서는 2학년이 36.2%로 자신의 치아가 건강하다는 응답이 높게 나타났으며, 학교에서 점심식사 후 이를 닦는 정도가 높을 수록 나타났으며(p<0.05), 건강하다고 응답한 집단은 치과에 가는 시기는 정기적으로 1년에 1~2번 간다가 타 집단보다 더 나타났고, 치과 방문 목적 또한 구강검사를 위해 방문이 나타났다(p<0.001). 따라서 학생들에게 지속적인 구강보건교육을 실시하여 학생들이 구강건강에 관심을 가질 동기부여의 기회를 제공해 주고, 대한 긍정적 태도가 가지게 함으로써 지식과 인식도를 높이고자 한다. This study was carried out in order to be used as...
A new staging system for multiple myeloma (MM) has utilized serum concentrations of beta2-microglobulin (Sbeta2M) and albumin as important prognostic factors survival. Since Sbeta2M is an indicator glomerular filtration rate, we compared the values 24-hr urinary creatinine clearance (Ccr) in patients with MM. We retrospectively reviewed records 170 MM from January 1996 to November 2003 whose Ccr was available at time diagnosis. found that pretreatment inversely related (Spearman's...
Moebius syndrome is a rare, congenital neurological disease involving facial paralysis and limitation of eye movements. It results from maldevelopment the sixth seventh cranial nerves. Dental features this include micrognathia, microstomia, tongue deformity, cleft palate, hypoplasia teeth, missing teeth. A 7-year-old female with was referred local dental clinic for caries treatment. She presented microstomia. Oral findings included multiple enamel hypoplasia, deformity. treatments including...
Objectives This study evaluated the relationship between oral hygiene and health status radiation-induced mucositis among patients with head neck cancer over an 8-week period. Methods We recruited 40 scheduled to receive radiation therapy (RT), 25 were included in study. Before commencing RT, a dentist examined for plaque, determined gingival index pocket depth. A dental hygienist assessed once weekly, 8 weeks, during RT. Results The mean patient age was 60.96 (±8.47) years, 21 (87.5%) male....
Objective: This retrospective propensity score–matched cohort study aimed to examine the frequency of acromioplasty among patients with shoulder disorders receiving and not acupuncture, based on Korea National Health Insurance Service-National Sample Cohort (NHIS-NSC) data. Methods: We included cases high-frequency disorders—adhesive capsulitis, rotator cuff syndrome, impingement sprain strain joint—stratified from NHIS-NSC database between 2002 2013; were classified into two groups a...
Adverse drug reactions (ADRs) affecting cardiovascular system might be underestimated and underreported in clinicalpractice. Most common culprit drugs are anthracyclines, antipsychotics cyclooxygenase (COX)-2 inhibitors. Anthracyclinesmay induce myocardial damage with oxidative stress, which is mostly irreversible. Type I ADRs commonly encountered inantipsychotic use. Attention should paid to the risk of sudden cardiac death related some antipsychotics. COX inhibitorspharmacologically have...
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