A5022744185- SARS-CoV-2 and COVID-19 Research
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Bacillus and Francisella bacterial research
- SARS-CoV-2 detection and testing
- RNA and protein synthesis mechanisms
- Travel-related health issues
- Antibiotic Resistance in Bacteria
- COVID-19 diagnosis using AI
- Parasite Biology and Host Interactions
- Helminth infection and control
- CRISPR and Genetic Engineering
- Respiratory viral infections research
- Zoonotic diseases and public health
- Pediatric health and respiratory diseases
- Parasitic Infections and Diagnostics
- Mollusks and Parasites Studies
Research Institute for Tropical Medicine
2019-2024
University of the Philippines Los Baños
2016
Abstract The Philippines has a high incidence of tuberculosis disease (TB), with an increasing prevalence multidrug-resistant Mycobacterium (MDR-TB) strains making its control difficult. Although the M . “Manila” ancient lineage 1 strain-type is thought to be prevalent in country, evidence export others, little known about genetic diversity circulating strains. By whole genome sequencing (WGS) 178 isolates from National Drug Resistance Survey, we found majority (143/178; 80.3%) belonged...
In the Philippines, rats and snails abound in agricultural areas as pests source of food for some local people which poses risks parasite transmission to humans such Angiostrongylus cantonensis . This study was conducted determine extent A. infection among collected from rice-farming villages Muñoz, Nueva Ecija. A total 209 rats, 781 freshwater snails, 120 terrestrial were study. Heart lungs snail tissues examined subjected artificial digestion collection. Adult worms identified using SSU...
Abstract The Omicron severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant led to a dramatic global epidemic wave following detection in South Africa November 2021. BA.1 lineage was dominant and responsible for most SARS-CoV-2 outbreaks countries around the world during December 2021–January 2022, while other lineages, including BA.2, accounted minority of isolates. Here, we describe Philippines by analysing genomic data. Our results identify presence both BA.2 lineages 2021,...
Abstract The Philippines is a high-incidence country for tuberculosis, with the increasing prevalence of multi- (MDR-TB) and extensively-drug (XDR-TB) resistant Mycobacterium tuberculosis strains posing difficulties to disease control. Understanding genetic diversity circulating can provide insights into underlying drug resistance mutations transmission dynamics, thereby assisting design diagnostic tools, including those using next generation sequencing (NGS) platforms. By analysing genome...
ABSTRACT Co-infection with multiple SARS-CoV-2 variants, though rare, may have clinical and public health implications, including facilitating variant recombination. Early detection of co-infections is therefore crucial. In this study, we report two probable cases co-infection identified during routine genomic surveillance. Initially suspected as cross-contamination due to the presence private mutations nucleotide mixtures flagged by Nextclade bammix, samples were re-extracted resequenced...
Abstract The Omicron SARS-CoV-2 variant led to a dramatic global epidemic wave following detection in South Africa November, 2021. lineage BA.1 was dominant and responsible for most domestic outbreaks during December 2021-January 2022, whilst other lineages including BA.2 accounted the minority of isolates. Here, we describe Philippines by analysing genomic data. Our results identify presence both 2021, before cases surged January 2022. We infer that only underwent sustained transmission...
Purpose: Out of more than 2400 patients with severe acute respiratory infections who travelled to the Philippines from Middle East since 2013, only two cases were confirmed positive for Respiratory Syndrome Coronavirus (MERS-CoV). Considering that these imported into country, it is important determine pathogen/s causing disease mitigate potential outbreaks may overburden country's health care system. Methods & Materials: Archived upper and lower samples (n = 203) collected 2014 2016 tested...