A5059742552- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Bacillus and Francisella bacterial research
- Mosquito-borne diseases and control
- COVID-19 epidemiological studies
- COVID-19 diagnosis using AI
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Dengue and Mosquito Control Research
- Malaria Research and Control
- Insect symbiosis and bacterial influences
- COVID-19 and healthcare impacts
- Viral Infections and Vectors
- Diverse Scientific Research Studies
- interferon and immune responses
- Immune responses and vaccinations
- COVID-19 Impact on Reproduction
- COVID-19 impact on air quality
- Infection Control and Ventilation
Research Institute for Tropical Medicine
2017-2024
Deakin University
2023
The novel coronavirus (COVID-19) is responsible for more fatalities than the SARS coronavirus, despite being in initial stage of a global pandemic. first suspected case Philippines was investigated on January 22, 2020, and 633 cases were reported as March 1. We describe clinical epidemiological aspects two confirmed COVID-19 Philippines, both admitted to national infectious disease referral hospital Manila.Both patients previously healthy Chinese nationals vacation travelling couple during...
Abstract Background Vector control measures are critical for the prevention and reduction of dengue virus (DENV) transmission. Effective vector is reliant not only on knowledge mosquito abundance, but also timely accurate detection mosquito-borne infection. Mosquito-based surveillance programs typically rely pool-based testing, although whether individual-based testing a feasible alternative to this has been widely studied. Applying an approach, we conducted 1-month study DENV in adult Aedes...
The recently emerged novel coronavirus, "severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)," caused a highly contagious disease called coronavirus 2019 (COVID-19). It has severely damaged the world's most developed countries and turned into major threat for low- middle-income countries. Since its emergence in late 2019, medical interventions have been substantial, relied on public health measures collectively known as nonpharmaceutical (NPIs). We aimed to centralize accumulative...
We report the first travel-related case of a possible Mpox-Varicella zoster virus (VZV) co-infection in Philippines, country that is endemic for Varicella but non-endemic Mpox. A 29-year-old Filipino, female, with travel history to Switzerland and no prior VZV infection sought consultation due rashes. She presented multiple papular, pustular, vesicular skin lesions, some umbilication irregular borders, on face, neck, trunk, inguinal area, upper extremities, right leg. also had bilateral...
ABSTRACT Co-infection with multiple SARS-CoV-2 variants, though rare, may have clinical and public health implications, including facilitating variant recombination. Early detection of co-infections is therefore crucial. In this study, we report two probable cases co-infection identified during routine genomic surveillance. Initially suspected as cross-contamination due to the presence private mutations nucleotide mixtures flagged by Nextclade bammix, samples were re-extracted resequenced...
We report a case of 31-year-old Filipino male with travel history to several European countries in July 2022. He developed five non-tender, well-defined, umbilicated pustules erythematous borders on the upper lip, left gluteal area, bilateral knees, and ankle. Skin punch biopsy findings were suggestive viral infection. Mpox infection from Clade II (previously known as West African clade) was confirmed by detecting amplifying G2R_G, G2R_WA C3L gene targets using qPCR. Shotgun metagenomic...
ABSTRACT Whole genome sequencing (WGS) is used extensively in identifying SARS-CoV-2 variants. However, this method requires stringent sample acceptance criteria, long turn-around time (TAT), expensive processing and maintenance costs, highly skilled staff. Although offers comprehensive pathogen insights, a cost-effective tool with faster TAT beneficial detecting variants of concern (VOCs). Here, we single nucleotide polymorphism (SNP) RT-qPCR assay to detect the N501Y mutation banked RNA...
Abstract BACKGROUND Following the detection of first laboratory-confirmed Monkeypox (MPXV) infection in Philippines, guidelines on diagnosis, treatment, and prevention have been strengthened to further help healthcare providers differentiating it properly from other diseases with similar clinical presentation, one which is Varicella zoster (VZV) infection. Interestingly, co-infection has previously reported endemic countries. We then report travel-related case MPXV-VZV a country that for but...
<title>Abstract</title> <italic>Background:</italic> With the World Health Organization’s declaration of 2022 multi-country monkeypox outbreak as a Public Emergency International Concern (PHEIC), we report first confirmed case infection in Filipino with clinical presentation different from classic cases previously reported endemic countries Central and West Africa before outbreak. We describe infection's gross dermatopathological appearances on Southeast Asian brown skin. also discuss...
To validate a method in detecting SARS-CoV-2 via RT-qPCR pregnant and non-pregnant samples other than nasopharyngeal swabs and/or oropharyngeal such as cervical, rectal, amniotic fluid, placental, umbilical cord blood, breastmilk.
Abstract Background: Vector control measures are critical in the prevention and reduction of dengue virus (DENV) transmission. In this context, an effective vector is reliant not only on knowledge mosquito abundance, but also timely accurate detection infection. Mosquito-based surveillance programs typically rely a pool-based testing, although whether individual-based testing could represent feasible alternative largely studied. Applying approach, we conducted one-month DENV adult Aedes...
Abstract Background: Vector control measures are critical in the prevention and reduction of dengue virus (DENV) transmission. In this context, effective vector is reliant not only on knowledge mosquito abundance, but also timely accurate detection infection. Mosquito-based surveillance programs commonly rely pool-based testing, whether individual-based testing could represent a feasible alternative largely studied. Applying an approach, we conducted one-month DENV adult Aedes aegypti...
Abstract Background Dengue virus (DENV) infection continues to be a major public health concern throughout tropical and subtropical regions of the world where Aedes aegypti mosquitoes, its primary vector, dwell. In context DENV transmission, effective control is reliant not only on knowledge mosquito abundance, but also infection. 2015 dengue season, we conducted one-month entomological surveillance adult mosquitoes around households suspected patients in Tarlac City, Philippines assess rate...
Abstract Background With the World Health Organization’s declaration of 2022 multi-country monkeypox outbreak as a Public Emergency International Concern (PHEIC), we report first confirmed case infection in Filipino with clinical presentation different from classic cases previously reported endemic countries Central and West Africa before outbreak. We describe infection's gross dermatopathological appearances on Southeast Asian brown skin. also discuss detailed process quantitative real-time...
<title>Abstract</title> <italic>Background:</italic> With the World Health Organization’s declaration of 2022 multi-country monkeypox outbreak as a Public Emergency International Concern (PHEIC), we report first confirmed case infection in Filipino with clinical presentation different from classic cases previously reported endemic countries Central and West Africa before outbreak. We describe infection's gross dermatopathological appearances on Southeast Asian brown skin. also discuss...