- Diabetes Treatment and Management
- COVID-19 Clinical Research Studies
- Pancreatitis Pathology and Treatment
- Metabolism, Diabetes, and Cancer
- Dermatologic Treatments and Research
- Herpesvirus Infections and Treatments
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Diet, Metabolism, and Disease
- Neuroblastoma Research and Treatments
- Myasthenia Gravis and Thymoma
- Drug Transport and Resistance Mechanisms
- Intestinal Malrotation and Obstruction Disorders
- SARS-CoV-2 and COVID-19 Research
- Sexual Differentiation and Disorders
- Peptidase Inhibition and Analysis
- Sperm and Testicular Function
- Lipoproteins and Cardiovascular Health
- Chronic Disease Management Strategies
- Infectious Encephalopathies and Encephalitis
- Artificial Intelligence in Healthcare
- Medication Adherence and Compliance
- Lipid metabolism and disorders
- Adrenal Hormones and Disorders
- Virus-based gene therapy research
University of Split
2021-2024
University Hospital Centre Zagreb
2020-2022
The recently emerged novel coronavirus, "severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)," caused a highly contagious disease called coronavirus 2019 (COVID-19). It has severely damaged the world's most developed countries and turned into major threat for low- middle-income countries. Since its emergence in late 2019, medical interventions have been substantial, relied on public health measures collectively known as nonpharmaceutical (NPIs). We aimed to centralize accumulative...
Background and Objectives: Scrotal swelling or hydrocele is a rare complication of acute pancreatitis described in the literature. We present case penoscrotal caused by first attack interstitial edematous alcohol-induced young male patient. Case report: A 22-year-old man was admitted to emergency unit due diarrhea vomiting since morning which followed severe abdominal pain. Urgent multislice CT scan showed steatosis, pancreatic peripancreatic fluid collection (interstitial pancreatitis)....
Objective: The research of basic knowledge about DM was carried out in order to determine the quality care for patients with diabetes. Respondents and Methods: conducted among 194 nurses/technicians University Hospital Split. A survey questionnaire (Table 1) used as a instrument, which consisted general data factors affecting DM, examination DM. 9 questions lasted 20 minutes, presence examiner, without any literature or mobile phones. Results: To question most common cause death diabetes,...
Sodium-glucose cotransporter-2 (SGLT2) inhibitors are a group of drugs that staple in diabetes treatment. Its representatives dapagliflozin and empagliflozin oftentimes used combination with other antidiabetic such as metformin. In this manuscript, we examine the interactions mixtures metformin water, varying concentration to better reflect drug ratios prescribed therapy. We found both SGLT2 have tendency hydrogen bond water rather than metformin, more bonds formed simultaneously lifetime...
Metformin is considered as the go-to drug in treatment of diabetes. However, it either prescribed lower doses or not at all to patients with kidney problems. To find a potential explanation for this practice, we employed atomistic-level computer simulations simulate transport metformin through multidrug and toxin extrusion 1 (MATE1), protein known play key role expulsion into urine. Herein, examine hydrogen bonding between MATE1 one more molecules. The simulation results indicate that...
Hypertriglyceridemia is a known but underestimated cause of acute pancreatitis. Although the connection between pancreatitis and type I, IV, V hyperlipoproteinemia has been described, using Fredrickson’s classification, IIb associated only reported in few more rare cases. That why we present female patient with recurrent hyperlipidaemic hyperlipidaemia.
Diabetes is a chronic, progressive metabolic disease that has now reached pandemic proportions. It’s estimated 10.5% of the world’s population diabetes, making it global challenge requires attention and innovative strategies from healthcare systems worldwide. While macrovascular complications remain leading cause death in diabetes patients, this study provides detailed description dermatological changes these individuals, with particular emphasis on severity diabetic foot conditions. Within...
Varicella is a highly contagious infectious disease that can cause various complications. One of them, epididymo-orchitis, rare and poorly described in literature, thus remains seldom thought of, under-diagnosed, treated. In this report we present the case 13-year-old boy initially examined by an infectologist pediatric surgeon under diagnosis scrotal bacterial superinfection during varicella infection. Wrongly treated with antibiotics, he was then endocrinologist, diagnosed...
Insulin resistance (IR) represents one of the key regulatory mechanisms in development non - alcoholic fatty liver disease. It is a common hepatocyte injury hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM). Higher plasma platelet-derived growth factor A (PDGF- A) concentration associated with increased hepatic steatosis fibrosis T2DM. PDGFs are regulators connective tissue formation potent mitogens for stellate cells. We investigated whether there an association between...
Syndrome of inappropriate antidiuretic hormone (SIADH) secretion is an endocrinological disorder which occurs when there evidence continued (ADH) in the absence appropriate osmotic volume stimulus. Most commonly it caused by different types cancer or medications (eg. diuretics, antidepressants, antipsychotics...). Secondary adrenal insufficiency insufficient adrenocorticotropic (ACTH) and cortisol production. In hypocortisolism, inhibitory mechanism on ADH vanishes causing increased leading...