A5071226035- PARP inhibition in cancer therapy
- RNA Interference and Gene Delivery
- Neuroendocrine Tumor Research Advances
- Acute Lymphoblastic Leukemia research
- Neurosurgical Procedures and Complications
- Cancer Cells and Metastasis
- Esophageal Cancer Research and Treatment
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Air Quality and Health Impacts
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- Spinal Hematomas and Complications
- Psoriasis: Treatment and Pathogenesis
- Global Educational Reforms and Inequalities
- Neutropenia and Cancer Infections
- Carcinogens and Genotoxicity Assessment
- Body Image and Dysmorphia Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Cancer, Stress, Anesthesia, and Immune Response
- Burn Injury Management and Outcomes
- Heat shock proteins research
- Economic and Environmental Valuation
- Facial Rejuvenation and Surgery Techniques
Zhejiang Cancer Hospital
2015-2023
Chinese Academy of Sciences
2023
Baoshan College
2023
Philips (United States)
2021
Tianjin Centers for Disease Control and Prevention
2019
Tongji University
2019
Optum (United States)
2015-2017
Long Island Association
2017
Soochow University
2012-2015
Shanghai Ninth People's Hospital
2009-2013
Radiotherapy is an important procedure for the treatment of inoperable non-small cell lung cancer (NSCLC). However, recent evidence has shown that irradiation can promote invasion and metastasis several types cancer, underlying mechanisms are not fully understood. This study aimed to investigate molecular mechanism by which radiation enhances invasiveness NSCLC cells. We found after irradiation, hypoxia-inducible factor 1α (HIF-1α) was increased translocated into nucleus, where it bound...
Abstract Background Radiation-induced skin injury remains a serious concern during radiotherapy. Cu/Zn-superoxide dismutase (Cu/Zn-SOD, SOD 1 ) is conserved enzyme for scavenging superoxide radical in cells. Because of the integrity cell membranes, exogenous molecule not able to be incorporated into cells, which limited application natural . The aim this study was evaluate protective role HIV-TAT protein transduction domain mediated (TAT-SOD against ionizing radiation. Methods recombinant...
Objective: We assessed the risk of liver injuries following low doses N,N-dimethylformamide (DMF) below threshold limit values (20 mg/m3) among leather industry workers and comparison groups. Methods: A cohort 429 from a factory 466 non-exposed subjects in China were followed for 4 years. Poisson regression piece-wise linear used to examine relationship between DMF injury. Results: Workers exposed cumulative dose significantly more likely than develop nonlinear injury was observed, 7.30...
Increasing occurrence of posterior reversible encephalopathy syndrome has been reported in children with acute lymphoblastic leukemia. However, the etiology is not clear. To study possible pathogenetic mechanisms and treatment this complication, we 11 cases pediatric leukemia who developed after induction chemotherapy. After appropriate treatment, clinical symptoms most disappeared even though chemotherapy continued. During 1-year follow-up, no recurrence was observed. Although imaging...
Objective: The zygomatic body and arch are usually prominent in Asians; therefore, malar reduction is one of the most popular procedures for aesthetic facial contouring. purpose this study was to establish a new option malarplasty analyze merits demerits conventional operative techniques, thus searched more effective reliable surgical procedures. Methods: Records 570 patients who underwent our center from 1988 2008 were reviewed study. Several introduced techniques used until an alternative...
This study aimed to determine the potential predisposing factors for development of febrile seizures among children with upper respiratory tract infection in eastern Chinese region. Participants were individuals aged 6 months and years (n = 189) who diagnosed seizure, complicated infection, 174 age-matched had without as controls. The viral antigens including influenza A B, parainfluenza, adenovirus, syncytial virus detected from nasopharyngeal aspirates. incidence was much higher patients...
The tetraspanin CD63 has been described to have critical roles in multiple biological processes, including tumorigenesis and metastasis several types of cancer. However, its role esophageal carcinoma (EC) not reported. In the current study, immunohistochemistry was used investigate expression 106 cancer samples, 49 adjacent esophagus tissues 17 normal mucosa tissues. results revealed that overexpression observed samples negatively correlated with tumor stage lymph node metastasis. To further...
This study aimed to investigate the aggressive behavior of triple‑negative breast cancer (TNBC) cells that had survived ionizing radiation and explore potential targets TNBC combination treatment. Consistent with previous literature, Axl was highly expressed in closely associated degree malignancy based on immunohistochemical staining. Using a gradient irradiation method, radiation‑resistant mouse cell line 4T‑1/IRR established. It found expression upregulated cells. After by X‑ray,...
Emerging contaminants in landfill leachate are causing environmental concerns due to their adverse impacts on the aquatic environment. The most popular biological process is mostly first stage combination with additional physical-chemical process. Current post-treatments limited by high operating costs, low treatment efficiencies, or sensitive conditions. Poly-aluminium(III)-magnesium(II)-sulfate (PMAS brief) used remove color and organic compounds secondary effluent of leachate. More than...
To observe the efficacy and toxicities of combined nimotuzumab with chemoradiotherapy as first-line treatment to advanced esophageal squamous cell carcinoma (ESCC).The clinical data 43 patients local or metastatic ESCC treated in our hospital were included this retrospective study. The overall response, adverse events, survival (OS), progressive-free (PFS) analyzed.At 1 month after treatment, objective response rate (complete [CR] + partial [PR]) was 65.12%, disease control (CR PR stable...
Radiation-induced reactive oxygen species (ROS) can damage DNA and most other biological macromolecules in skin radiation-induced injury is a serious concern for radiation therapy.Skin possesses an extremely efficient antioxidant system, which conferred by two systems: enzymes small molecules that scavenge ROS donating electrons.Amphibian multifunctional organ, protects against dangers of various oxidative stresses.Recently, peptide called RP-1 was isolated from the secretions Rana pleurade,...
Abstract Objective To compare the effectiveness of different radiotherapy techniques – tomotherapy (TOMO) and intensity‐modulated radiation therapy (IMRT) for patients with esophageal carcinoma on basis dosimetric analysis. Methods The target areas organs at risk in 10 were underlined transmitted to Raystation TOMO planning systems. homogeneity index (HI) conformal (CI) values, dose distributions compared dose–volume histograms parameters. Results median HI gross volume by (HI = 0.0575)...
Circulating tumor DNA (ctDNA) is a kind of cell-free which comes from cells and effectively reflects the molecular characteristics tumors, providing us novel method to explore its clinical therapeutic value in advanced lung cancer.A total 36 patients with non-small cell cancer (NSCLC) were enrolled this study, including 28 cases adenocarcinoma 8 squamous carcinoma. Next-generation sequencing based ctDNA detection, tissue (tDNA) corresponding survival analysis, retrospective statistics...
Management of postoperative surgical site infection (SSI) is a huge challenge to orthopedic surgeons, and significantly impacts patients their families due long treatment cycles associated discomfort experiences.A 68-year-old woman without medical history any comorbidities, diabetes, hypertension, allergies, or tuberculosis, was admitted our hospital complaining right knee pain following fall. X-ray CT scans revealed closed patella fracture. The patient underwent open reduction internal...
Abstract As the amount of municipal garbage has grown rapidly, hidden perils environment have become increasingly outstanding and needed to be resolved. This paper selects Yangpu District Shanghai as research object, quantify positive influence classification recycling. After dry wet method in source is obtained, per ton can impacts amounts 256.97 Yuan. Although concept new prospect broad, there are still many challenges current classification. Therefore, this tries put forward some...