A5047131184- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Nail Diseases and Treatments
- Skin Protection and Aging
- Plant Pathogens and Fungal Diseases
- Dermatologic Treatments and Research
- Cutaneous lymphoproliferative disorders research
- Asthma and respiratory diseases
- Fungal Biology and Applications
- Contact Dermatitis and Allergies
- Acne and Rosacea Treatments and Effects
- Allergic Rhinitis and Sensitization
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Laser Applications in Dentistry and Medicine
- melanin and skin pigmentation
- Autoimmune Bullous Skin Diseases
- Drug-Induced Adverse Reactions
- Nonmelanoma Skin Cancer Studies
- Cutaneous Melanoma Detection and Management
- Botulinum Toxin and Related Neurological Disorders
- Genetic and rare skin diseases.
- Urticaria and Related Conditions
- Bee Products Chemical Analysis
- Health Systems, Economic Evaluations, Quality of Life
Konkuk University
2015-2024
Emory Healthcare
2024
Emory University
2024
Incheon St. Mary's Hospital
2024
Catholic University of Korea
2017-2024
Konkuk University Medical Center
2010-2022
Bucheon St. Mary's Hospital
2017
Novartis (United States)
2016
Gwangju University
2013
In-Q-Tel
2013
Background: Seborrheic keratosis (SK) is one of the most common epidermal tumors skin.However, only a few large-scale clinicohistopathological investigations have been conducted on SK or possible correlation between histopathological subtype and location.Objective: The aim this study was to analyze clinical features relatively large number cases diagnosed SK.Methods: Two hundred seventy-one pathology slides skin tissue from patients with clinically 206 biopsy-proven were analyzed.The...
BACKGROUND Botulinum toxin (BTX) has been used cosmetically with good clinical efficacy and tolerable safety. OBJECTIVE This randomized, double-blind, split-face study aimed to investigate the safety of intradermal BTX in patients rosacea. MATERIALS AND METHODS Twenty-four participants were enrolled randomly given injections normal saline both cheeks. Clinician Erythema Assessment (CEA) score, Global Aesthetic Improvement Scale (GAIS) skin hydration, transepidermal water loss (TEWL), melanin...
Abstract With the recent availability of culture‐independent sequencing methods, studies have been conducted to analyse skin micro‐organisms present in patients with atopic dermatitis ( AD ). However, database on fungal communities, “mycobiome,” has relatively restrictive compared bacterial world. We aimed comparatively overall mycobiome between and healthy individuals Korean population. analysed swab samples obtained from antecubital fossae 8 controls. Using method followed by direct DNA...
Abstract Although many epidemiological surveys for patients with psoriasis have been reported based on individual countries or facilities, there has no study encompassing the major region in Asia. The Asian Society Psoriasis (ASP) conducting an across various and regions to elucidate compare epidemiology of psoriasis. A total 1948 cases were analyzed, 938 from Japan, 530 China, 325 Korea, 141 Chinese Taipei, 14 Thailand, all which enrolled between 2020 2022. In total, male–female ratio was...
Psoriasis is a chronic inflammatory skin disease. It assumed that the plaque phenotype of psoriasis associated with T helper (Th) 1 immune response activation, while guttate Th17 response. Previous investigations differences in serum levels cytokines relative to clinical psoriatic have yielded conflicting results. This study compared circulating and LL-37 morphological patients psoriasis. Seventy-four age-matched (32 42 psoriasis) 12 healthy controls were included. A multiplex cytokine assay...
ABSTRACT Previous studies have shown that topical steroid and shampoo containing zinc pyrithione provide clinical benefits for treatment of scalp seborrheic dermatitis. But the efficacy tacrolimus, a newly developed calcineurin inhibitor on dermatitis, is not well investigated yet. We wanted to compare tacrolimus with conventional (zinc betamethasone) dermatitis scalp. Patients were randomly allocated receive betamethasone, or shampoo. Some patients instructed continue treatments 8 weeks...
Plaque-type psoriasis manifests with various morphological phenotypes and different clinical activity over time in the same individual or from one patient to another. Circulating cytokines, especially T-helper (Th) 1- Th17-related, have been suggested reflect inflammatory nature of psoriasis. However, studies regarding cytokine profile according are quite scarce.We sought analyse circulating Th1 Th17 cytokines phenotype investigated correlation between disease severity [Psoriasis Area...
Ultraviolet (UV) irradiation affects the function and complexion of skin by inducing changes in physical properties through formation erythema, proliferation epithelial cells, DNA damage, activation or inactivation various enzymes proteins, free radical formation. In this study, authors intended to observe overall course barrier reflectance induced photodamage, healing reaction time, alteration complexion.The subjects were chosen from 15 healthy Korean men 20-35 age, that fall into category...
Malassezia yeasts are normal flora of the skin found in 75~98% healthy subjects. The accurate identification species is important for determining pathogenesis with regard to various diseases such as folliculitis, seborrheic dermatitis, and atopic dermatitis.This research was conducted determine a more rapid molecular test classification yeasts.We compared accuracy efficacy restriction fragment length polymorphism (RFLP) nested polymerase chain reaction (PCR) yeasts.Although both methods...
Fractional photothermolysis makes thousands of minute areas called microthermal treatment zones on the skin surface and transmits thermal injury to facilitate heat shock protein formation around dermis. Potential side effects include acneiform eruption, herpes simplex virus outbreak, erythema, post-inflammatory hyperpigmentation.To investigate compare changes in Asian patients after two different fractional systems (FPS) a split face.A half-split face study was performed with 10,600 nm...
The yeasts of the genus Malassezia are members normal flora on human skin and they found in 75~80% healthy adults. Since its association with various disorders have been known, there a growing number reports that implicated yeast atopic dermatitis (AD).The aim present study is to isolate species from AD patients by using 26S rDNA (ribosomal Deoxyribonucleic acid) PCR-RFLP investigate relationship between positive culture severity AD.Cultures for were taken scalp, cheek, chest, arm thigh 60...
Background: Although ablative fractional resurfacing is known to be effective against photoaging and acne scars, studies on its efficacy, safety changes in the skin characteristics of Asians are limited.Objective: The aim this study assess efficacy carbon dioxide laser (CO2FL) Koreans treated for wrinkles define during recovery period.Methods: We administered one session CO2FL 10 scar patients 14 with types IV V.The surveillance side effects along measurement biophysical properties was...
Psoriasis is an immune-mediated, chronic inflammatory disease affecting multiple aspects of patients' lives. Its epidemiology varies regionally; however, nationwide epidemiologic data on psoriasis depicting profile Korean patients has not been available to date.
Background: The mid-dermal injection of stabilized hyaluronic acid–based gel nonanimal origin has been shown to be an effective method for skin rejuvenation. previous manual technique, using a prefilled syringe, made it difficult precisely control the into layers and achieve even distribution across area. This single-center, evaluator-blinded, prospective, split-face, randomized controlled trial investigated efficacy safety acid stamp-type electronic multineedle injector. Methods:...
Summary This study concerns a culture research based on the data gathered from Korean subjects to examine distribution of Malassezia yeast. yeast were cultivated out samples scalp, forehead, chest, arm and thigh. restricta was recovered more frequently in teens young adults, while M. globosa predominant species older than 50 years age. The population density significantly higher age group (AG) 21–30 compared with other AGs ( P < 0.05). It also chest thigh key is recognise existence...
Fibroelastolytic papulosis of the neck (FEPN) encompasses a spectrum two disorders that were previously reported as pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) and white fibrous (WFPN). The clinical presentation FEPN is asymptomatic to mildly pruritic whitish-yellow papules may coalesce into cobblestone patterned plaques resemble elasticum (PXE). histology characterized by decrease or loss elastic fibers in dermis this sometimes accompanied minimal nodular increase...
Background: Multiplex polymerase chain reaction (PCR) allows more than two target DNA molecules to be amplified with primers.This method is also useful for detecting various other organisms simultaneously within a single test tube, and the scope of its use has been expanding widely in field clinical microbiology recent years.Objective: To assess value multiplex PCR identification dermatophytes.Methods: Using three speciallydesigned primers which contained ITS1-2, 18S rRNA, 28S rRNA regions,...
Background: The phenotypic heterogeneity of psoriasis could be explained by the alternate activation either T-helper (Th)-1-or Th-17-related cytokines.However, evidence directly supporting this hypothesis is scarce.Objective: To characterize expression Th-1-and cytokines according to morphological phenotype: guttate vs. plaque.Methods: In study, we enrolled 68 patients exhibiting or plaque psoriasis, and 10 healthy controls.To avoid age-related bias, age matching was performed for each...
Seborrheic dermatitis (SD) is a multifactorial disease; Malassezia species play an important role in its pathogenesis. We aimed to determine whether cream containing climbazole/piroctone olamine (C/P cream), antifungal agents with expected efficacy against species, could improve SD symptoms. instructed 24 patients mild-to-moderate apply the C/P and emollient on right left sides of face, respectively, every morning evening for 4 weeks. The casual sebum level (measured Sebumeter®; Courage &...
Background/purpose: The assessment of the sensitivity human skin to ultraviolet (UV) radiation is important in area phototherapy, photodermatoses, photo‐aging, photo‐carcinogenesis, and photo‐protection. Some reports have shown that quantitatively measured color a good indicator for predicting UV Caucasians. In this study, our aim was define correlation between phototype assessed by Fitzpatrick method Asian brown skin. Methods: A total 180 medical students with similar life styles were...