A5034232136- Glass properties and applications
- Clay minerals and soil interactions
- Autophagy in Disease and Therapy
- Zeolite Catalysis and Synthesis
- Bone Metabolism and Diseases
- Building materials and conservation
- Mass Spectrometry Techniques and Applications
- Mitochondrial Function and Pathology
- Oral and gingival health research
- Aquaculture disease management and microbiota
- Cancer, Hypoxia, and Metabolism
- Aquatic Ecosystems and Phytoplankton Dynamics
- Laser Applications in Dentistry and Medicine
- Water Quality Monitoring and Analysis
- Pharmacological Effects and Assays
- Geotechnical and construction materials studies
- Photodynamic Therapy Research Studies
- Electrochemical Analysis and Applications
- Environmental Toxicology and Ecotoxicology
- Mesoporous Materials and Catalysis
- School Choice and Performance
- Gut microbiota and health
- CRISPR and Genetic Engineering
- Spectroscopy and Quantum Chemical Studies
- Global Educational Reforms and Inequalities
Osaka Dental University
2022-2025
Shanghai Ocean University
2024
Ministry of Agriculture and Rural Affairs
2024
Daping Hospital
2023-2024
Army Medical University
2023-2024
Dalian Medical University
2022
Second Affiliated Hospital of Dalian Medical University
2022
Thomas Cole Historic House
2006-2010
University of Pennsylvania
2002
Jilin University
2000
In clinical practice, mini-screws of titanium-6-aluminum-4-vanadium alloy with an extra low interstitial (ELI) grade (Ti-6Al-4V ELI) are widely used as orthodontic anchorages. However, in treatment, Ti-6Al-4V mini-screw failure because peri-implantitis is a major challenge. To prevent damage caused by peri-implantitis, we developed novel disc/screw coated poly(lactide-co-glycolide) incorporating fisetin, naturally occurring flavonoid anti-inflammatory and antiosteoclastogenic/osteogenic...
Abstract Human gingival fibroblasts (HGnFs) maintain periodontal tissue homeostasis through active proliferation and migration. Clinically, it is considered that the wound-healing ability of maintained even in environments with insufficient supply nutrients, such as glucose, immediately after surgery. However, effects glucose-deficient on HGnFs remain unclear. This study aimed to investigate low-glucose environment homeostasis. We evaluated wound healing by examining cell migration collagen...
Gingival tissue experiences an environment of nutrient shortage, such as low glucose conditions, after periodontal surgery. Our previous studies found that this condition inhibits normal gingival cell functions. However, the mechanism by which glucose-deficient causes cellular damage to human fibroblasts (HGnFs) remains unclear. This study aimed investigate biological effects ROS induction on HGnFs under conditions. levels and anti-ROS ability different concentrations were evaluated...
Clenbuterol (CBL) is a potent beta(2)-adrenoceptor agonist used for the management of respiratory disorders in horse. The detection and quantification CBL can pose problem due to its potency, relatively low dose administered horse, slow clearance plasma concentrations. Thus, sensitive method confirmation racehorses required study distribution elimination. A fast was developed presence equine plasma, urine tissue samples. involved liquid-liquid extraction (LLE), separation by liquid...
Abstract Endometrial cancer (EC) is one of the most common cancers among women, while incidence EC rising. Many studies have found that Kinesin family member 15 (KIF15) highly expressed in a series cancers, but role KIF15 unclear. We detected expression level microarray tissues by immunohistochemical staining (IHC), and analyzed correlation between pathological characteristics patients. After inhibit cells with lentivirus, cell proliferation apoptosis were respectively CCK8 assay, flow...
Intracellular nutrient metabolism, particularly the metabolism of essential amino acids (EAAs), is crucial for cellular functions, including energy production and redox homeostasis. An EAA deficiency can lead to dysfunction oxidative stress. This study explores mechanisms underlying responses starvation, focusing on ROS-induced DNA damage apoptosis. MC3T3-E1 cells were subjected various assays conducted assess cell proliferation, survival, damage, The antioxidant N-acetylcysteine (NAC) was...
Periodontitis is an inflammatory lesion in the periodontal tissue. The behavior of human ligament stem cells (hPDLSCs), which play important role tissue regeneration, restricted by influence mediators. Photobiomodulation therapy exerts anti-inflammatory effects. purpose this study was to investigate effects light-emitting diode (LED) irradiation on responses hPDLSCs. light source a red LED (peak wavelength: 650 nm), and total absolute irradiance 400 mW/cm2. response hPDLSCs induced tumor...
Hypoxic pulmonary hypertension (HPH) is a progressive cardiopulmonary system disease characterized by vascular remodeling. Its occurrence and progression are closely related to oxidative stress. Lycopene, extracted from red vegetables fruits, exhibits particularly high antioxidant capacity that beneficial for cardiovascular diseases. Nevertheless, the role mechanism of lycopene in HPH remain unknown. Here, we found reversed elevated right ventricular systolic pressure (RVSP), hypertrophy,...
Determination of the genomic copy number Cre transgene is critical for establishment transgenic animal models. We demonstrate a real-time quantitative polymerase chain reaction (RT-qPCR) based method determination improved (iCre), which was tested in mouse model CYP19A1-iCre. The standards were derived from tandem repeats iCre fragments constructed by new application megaprimer PCR. Two rounds PCR used to obtain specific fragments, subsequently cloned into pUCm-T vectors. After IL-2...
糖尿病は歯周病の主要なリスクファクターの一つで，Periodontal Medicineに関する全身疾患の一つである。糖尿病の状態を模倣するとき，過栄養すなわち高濃度のグルコース環境を使用することが多い。しかし最近は高齢化に伴う低栄養が問題になることが多いが，低栄養が硬組織再生に及ぼす影響は不明である。本研究ではグルコース欠乏状態におけるマウス骨芽細胞における硬組織分化に及ぼす影響について検討した。