Lower extremity musculoskeletal computational models play an important role in predicting joint forces and muscle activation simultaneously are valuable for investigating functional outcomes of the implants. However, current total knee replacement rarely consider bearing surface geometry implant. Therefore, these lack detailed information about contact loading motion which factors evaluating clinical performances. This study extended a rigid multi-body dynamics simulation lower model to...

Mal-rotation of the components in total knee arthorplasty (TKA) is a major cause postoperative complications, with an increased propensity for implant loosening or wear leading to revision. A musculoskeletal multi-body dynamics model was used perform parametric study effects rotational mal-alignments TKA on loading under simulated walking gait. The contact forces were found be more sensitive variations varus-valgus rotation both tibial and femoral internal-external component TKA....

Flatfoot is linked to secondary lower limb joint problems, such as patellofemoral pain. This study aimed investigate the influence of medial posting insoles on mechanics extremity in adults with flatfoot. Gait analysis was performed fifteen young flatfoot under two conditions: walking shoes and foot orthoses (WSFO), (WS) random order. The data collected by a vicon system were used drive musculoskeletal model estimate hip, patellofemoral, ankle, lateral tibiofemoral contact forces. forces...

Understanding the coordination between pelvis and lower limbs in individuals with hemiplegic gait is crucial for deciphering their walking patterns. While studies have focused on limb kinematics stroke patients, research pelvis-lower remains limited. This study aims to assess patients using statistical parametric mapping (SPM) smartphonebased markerless motion capture. Seventeen twenty healthy were recruited collect locomotion data dual smartphone videos. For comparison, time-series of...

Compared with total knee arthroplasty, unicondylar replacement has the advantage of preserving tissue structure and motor function to greatest extent. Pre-clinical in-vitro test is an important tool evaluate safety effectiveness prostheses, it also a key focus product registration process. Through collection, comparison, analysis current regulations, technical standards, guidelines, related research literature, this paper expounds on relevant methods for pre-clinical in-vitrotesting...

Prosthesis loosening is the leading cause of postoperative revision in unicompartmental knee arthroplasty (UKA). The deviation medial and lateral translational installation prosthesis during surgery a common clinical phenomenon an important factor increasing risk loosening. This study established UKA finite element model bone-prosthesis fixation interface micromotion prediction model. predicted contact force joint motion from patient-specific lower extremity musculoskeletal multibody...

Conventional cannulated screws are commonly used for internal fixation in the treatment of vertical femoral neck fractures. However, noticeably high rates undesirable outcomes such as nonunion, malunion, avascular necrosis, and failure still troubled patients surgeons. It is urgent to develop new improve above clinical problems. The purpose this study was design a novel magnesium-titanium hybrid screw further evaluate its biomechanical performance A designed, conventional titanium also...

Musculoskeletal lower limb models are widely used to predict the resultant contact force in hip joint as a non-invasive alternative instrumented implants. Previous musculoskeletal based on rigid body assumptions treated an ideal sphere with only three rotational degrees of freedom. An model that considered force-dependent kinematics additional translational freedom was developed and validated this study by comparing it previous experimental measurement. A 32-mm femoral head against...

Detailed knowledge of the in vivo loading and kinematics knee joint is essential to understand its normal functions aetiology osteoarthritis. Computer models provide a viable non-invasive solution for estimating during different physiological activities. However, tibiofemoral patellofemoral joints gait cycle were not typically investigated concurrently previous computational simulations. In this study, natural architecture was incorporated into lower extremity musculoskeletal multibody...

Abstract Implant loosening and bearing surface wear remain the most common failure problems of total ankle arthroplasty (TAA). One main factors leading to these is nonphysiologic design articular surfaces. The goals this study were reveal effects anatomical medial‐lateral borders height differences, coronal sagittal radii on joint kinematics, contact mechanics, implant‐bone micromotion in TAA. A previously developed validated musculoskeletal (MSK) multibody dynamics (MBD) modeling method TAA...

Tibiofemoral contact forces in total knee replacement have been measured at the medial and lateral sites respectively using an instrumented prosthesis, predicted from musculoskeletal multibody dynamics models with a reasonable accuracy. However, it is uncommon that are applied separately to replace axial load according ISO standard majority of current finite element analyses. In this study, we quantified different effects applying loads versus traditional application on mechanics wear...

The two-dimensional (2D) superlattice obtained by self-assembly of gold nanoparticle (NPs) at the air–liquid interface shows a wide range potential applications in catalysis, sensing, electronic storage, and molecular recognition. However, dynamic assembly process NPs is still unclear. In this study, grafted with thiol-terminated polystyrene homopolymers (AuNPs@PS) were used as unit, 2D AuNPs@PS was prepared spreading evaporating toluene suspension air/diethylene glycol interface. effects...