- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Lower Extremity Biomechanics and Pathologies
- Diabetic Foot Ulcer Assessment and Management
- Orthopedic Surgery and Rehabilitation
- Drug-Induced Hepatotoxicity and Protection
- Glutathione Transferases and Polymorphisms
- Advanced biosensing and bioanalysis techniques
- Genomics, phytochemicals, and oxidative stress
- Sports injuries and prevention
- Gut microbiota and health
- Balance, Gait, and Falls Prevention
- Infant Nutrition and Health
- Hydrogen's biological and therapeutic effects
- T-cell and B-cell Immunology
- Neonatal Respiratory Health Research
- Biosensors and Analytical Detection
- Pediatric health and respiratory diseases
- Spine and Intervertebral Disc Pathology
- Parasitic infections in humans and animals
- Muscle activation and electromyography studies
- Medical Imaging and Analysis
- Immune Cell Function and Interaction
- Stroke Rehabilitation and Recovery
- Erythrocyte Function and Pathophysiology
Shanghai Sixth People's Hospital
2023-2025
Shanghai Jiao Tong University
2022-2025
Huashan Hospital
2016-2025
Fudan University
2016-2025
Zhejiang University
2024-2025
Ministry of Agriculture and Rural Affairs
2024
Children's Hospital of Capital Institute of Pediatrics
2024
Northwest University
2023-2024
Southwest University of Science and Technology
2024
Civil Aviation Flight University of China
2024
Extracting muscle synergies from surface electromyographic signals (sEMGs) during exercises has been widely applied to evaluate motor control strategies. This study explores the relationship between upper-limb and performance of joystick manipulation tasks. Seventy-seven subjects, divided into three classes according their maneuvering experience, were recruited perform left right reciprocation joystick. Based on motion encoder data, was evaluated by mean error, standard deviation, extreme...
As the largest mucosal surface, gut has built a physical, chemical, microbial, and immune barrier to protect body against pathogen invasion. The disturbance of microbiota aggravates pathogenic bacteria invasion injury. Fecal transplantation (FMT) is promising treatment for microbiome-related disorders, where beneficial strain engraftment significant factor influencing FMT outcomes. aim this research was explore effect on antibiotic-induced microbiome-disordered (AIMD) models infected with...
Hallux valgus (HV) deformity is closely correlated to the hypermobility of first metatarsal-cuneiform joint, but adequate understanding three-dimentional (3D) mobility this joint in normal or HV feet lacking. This study was conducted investigate multiple planes during body weight-bearing conditions for both and patients. A total 10 female volunteers (20 feet) patients participated study. Using a custom-made foot-loading device, computerized tomography (CT) scans each pair were taken under...
Abstract BACKGROUND Herbicide safeners mitigate crop damage without reducing herbicide efficacy. Here, the protective effects of phenoxyacetyl oxazolidine derivatives as potential were evaluated with a view toward injury caused by sulfonylurea nicosulfuron to sensitive maize varieties. RESULTS Growth indices demonstrated that bioactivity compound 9 ( N ‐phenoxyacety‐2‐methyl‐2,4‐diethyl‐1,3‐oxazolidine) was superior R‐28725 and all other compounds tested. Compound induced endogenous...
<title>Abstract</title> Personalized weight-bearing rehabilitation is crucial for orthopedic lower limb postoperative patients with different health backgrounds. However, physical therapists are in significant shortage, and the effectiveness of one-size-fits-all plans varies greatly. Here, using full-chain data from hospitalization to over 1,200 across 25 medical institutions, a comprehensive AI-driven system was proposed as Virtual Physical Therapist (VPT). The achieves automatic...
Background Solanum nigrum is a herbaceous perennial plant, which widely used in traditional medicine systems for its antioxidant, antiulcerogenic, antitumorigenic, and anti-inflammatory characteristics. The purpose of this study was to investigate the protective effects S. against alcoholic liver damage primary hepatocytes mice, using glutathione S-transferase alpha 1 (GSTA1) as an indicator. Methods Primary were obtained by inverse perfusion method improved on Seglen two-step situ. Results...
Nitrofuran (NF) is a class of broad-spectrum antibiotics that are used illegally in animal feeding. NF and its metabolites have proven to pose potential risk human health. To address the current analytical needs quantify low levels foods, sensitive method was developed for simultaneous detection four fish products by an ultraperformance liquid chromatography-diode array detector (UPLC-DAD). With 2-nitrobenzaldehyde (2-NBA) as derivatizing reagent, were hydrolyzed derivatized under assistance...
Naoxintong (NXT), a Chinese Materia Medica standardized product, extracted from 16 various kinds of traditional herbal medicines including Salvia miltiorrhiza, Angelica sinennsis, Astragali Radix, is clinically effective in treating atherosclerosisrelated diseases. Here, we tested the hypothesis that anti-atherosclerosis effects NXT might be mediated by suppressing maturation dendritic cells (DCs) mice model atherosclerosis. LDLR-/- fed high-fat diet were treated with placebo, (0.7g/kg/d,...
Abstract Backgrounds There has long been a consensus that shortening of the first metatarsal during hallux valgus reconstruction could lead to postoperative transfer metatarsalgia. However, appropriate is sometimes beneficial for correcting severe deformities or relieving stiff joints. This study investigate, from biomechanical perspective, whether and how much be allowed. Methods A finite element model human foot simulating push-off phase gait was established. Progressive 2 8 mm at an...
Lisfranc injuries are a disruption of one or more the tarsometatarsal joints and have an estimated incidence 1/55 000 people. However, total number could be underreported, because almost 20% these initially missed. Because relative infrequency injuries, current literature is inconsistent in regard to proper treatment. This article provides review complex including relevant anatomy, diagnosis, treatment, classifications, operative approaches, outcomes complications. Based on existing...
Here, a novel rapid and ultrasensitive aptamer biosensor was designed for target-induced activation of AIE effect followed by the Crispr Cas12a (LbCpf1)-mediated cleavage to achieve dual-signal detection. The prepared DNA building blocks contain target aptamer, ssDNA-Fc, Activator1. In this system, mode divided into two steps. First, when interacts with aptamers, would be disintegrated rapidly, releasing mass Ac1, generating ETTC-dsDNA aggregated produce fluorescence signal effect. Second,...
Ankle joint kinematics is mainly stabilized by the morphology of talar dome and articular surface tibiofibular mortise as well medial lateral ligament complexes. Because this bicondylar geometry talus believed to be crucial for ankle implant design. However, little data exist describing precise anatomy talocrural axis. The aim study document axis using three-dimensional (3D) computed tomographic (CT) modeling. Seventy-one participants enrolled CT scanning 3D model reconstruction. All ankles...
Transmembrane signal transduction is of profound significance in many biological processes. The dimerization cell-surface receptors one prominent mechanism by which signals are transmitted across the membrane and trigger intracellular cascade amplification reactions. Recreating such processes artificial systems has potential applications sensing, drug delivery, bioengineering, providing a new route for deep understanding fundamental However, it remains challenge to design working receptor...
A proper combination of implant materials for Total Ankle Replacement (TAR) may reduce stress at the bearing component and resected surfaces tibia talus, thus avoiding failure or aseptic loosening bone-implant interface.A comprehensive finite element foot model implanted with INBONE II system was created loading second peak ground reaction force simulated. Twelve material combinations including four tibial talar components (Ceramic, CoCrMo, Ti6Al4V, CFR-PEEK) three (CFR-PEEK, PEEK, UHMWPE)...