Abstract Uncrossable lesions are those that cannot be crossed with a balloon after successful guidewire crossing. These challenging and commonly encountered in tortuous calcified arteries as well chronic total occlusions. They the second most common barrier to PCI CTO intervention inability cross segment guidewire. Procedures involving uncrossable during routine utilise longer procedural times, radiation dose contrast volumes lower likelihood of success. In this article, we describe...

A middle-aged man with no previous cardiac history was admitted to the hospital being treated for thigh cellulitis, during his stay he developed palpitations and tachycardia which on initial ECG showed atrial flutter a 2:1 AV block evidence of an accessory pathway. He subsequently given nodal blocking agents in form beta-blockers (bisoprolol) slow heart rate down; unfortunately, this led hemodynamic instability due 1:1 conduction down This case report demonstrates importance recognising...

Aims:There are limited data on aspirin (ASA) desensitization for patients with coronary disease. We present our experience a rapid nurse-led oral regimen in sensitivity undergoing angiography. Methods:This single-center retrospective observational study includes history of ASA angiography intent to perform percutaneous intervention (PCI). Results:Between January 2012 and 2017, 24 stable disease (7 cases) or acute syndromes (non-ST-segment myocardial infarction [NSTEMI; 8 cases], STEMI [9...

Abstract Objectives We assessed the impact of diabetes mellitus (DM) on mortality after percutaneous coronary intervention (PCI) for left main stem (LMS) disease. Second, we compared outcomes between non‐insulin treated (NITDM) and insulin (ITDM) in different clinical settings. Background There is a paucity “real world” data diabetic patients undergoing LMS PCI. Methods undertook retrospective analysis consecutive unprotected PCI at 2 high volume tertiary centers. Diabetic status setting...

The role of balloon aortic valvuloplasty (BAV) in the era transcatheter valve replacement remains a topic debate. We sought to study safety and feasibility combined BAV percutaneous coronary intervention (BAV-PCI).

Cardiac troponins have emerged over recent years as the "gold standard" serum biochemical marker for diagnosis and management patients with acute myocardial infarction (MI). The relationship between old (creatine kinase; CK) new (troponin T; TT) markers of injury were examined in this study 392 consecutive admitted to a district hospital an MI. Significant correlation TT peak CK levels seen (R = 0.58, p<0.0001) all types A significant was also according type MI (Q wave or non-Q MI) level....

Objectives: To compare the long term outcomes between minimally invasive mitral valve repair (MiMVR) and conventional surgery. Current retrospective comparisons techniques frequently report echocardiographical (echo) early after surgery rarely them later. Methods: Patients were selected for MiMVR by surgical multi-disciplinary meeting from June 2008-March 2013. included had at least two transthoracic post-operative echocardiograms. Echocardiographic parameters including left ventricular size...

The uptake of CTO-PCI and the use hybrid approach have increased widely; this has resulted in a new set complications, some which are unusual, particularly with retrograde approach. We present case rare complication septal collateral perforation resulting formation hematoma that fortunately on occasion did not result any significant clinical deterioration, was managed conservatively successful outcome. However, other occasions, outcome can be more serious.

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Canine inflammatory bowel disease (IBD) is a progressive with poorly characterized etiology. We sought to gain insight into the metabolic disturbances preceding and co‐incident canine IBD by comparing plasma metabolome clinical indices of dogs (n =30) prior subsequent diagnosis histopathological assessment intestinal tissue collected endoscopy. Archived samples were generated from annual health screens adventitious health‐related collections curated according status their donors. Metabolomic...

Abstract Objectives To study the relationship between diabetes mellitus (DM) and left ventricular (LV) function on outcomes following percutaneous coronary intervention (PCI). Background DM is a growing public health challenge worldwide significant risk factor for cardiovascular disease heart failure. Methods All PCI procedures performed 2006 2013 with LV diabetic status recorded in BCIS‐NICOR database were included. Demographic, procedural, clinical data collected. Multivariable logistic...

The PRAMI and CvLPRIT trials support preventive percutaneous coronary intervention (PCI) for multivessel disease found during ST-segment elevation myocardial infarction (STEMI). We assess our real-world experience of the management identified primary PCI (PPCI) in a large UK regional centre.All STEMI patients who underwent culprit-only PPCI study period (August 2011 to August 2013) were retrospectively assessed eligibility each trial. two resulting groups designated as 'observational'...

Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications Network Open Cardiology Dermatology Health Forum Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) JN Learning / CMESubscribeJobsInstitutions LibrariansReprints Permissions Terms Use Privacy...

<h3>Background</h3> NICE guideline CG95 for investigating chest pain of new onset (http://www.nice.org.uk/guidance/cg95) recommends calculating the Pryor risk score to determine significant coronary artery disease (CAD). Significant CAD is defined as a lesion &gt;70% in major epicardial or &gt;50% left main stem (box 1 guideline). Patients with calculated 61–90% should be investigated using invasive angiography. <h3>Aim</h3> This study evaluates how use has altered pickup rate on...

<h3>Introduction</h3> The RCTs, PRAMI¹ and CVLPRIT,² have suggested that preventative PCI for multi-vessel disease identified during PPCI improves outcomes with higher rates of cardiovascular events in the culprit-only cohorts. <h3>Methods</h3> 1143 consecutive STEMIs at our centre from August 2011–2013 were retrospectively assessed eligibility to one or both trials. 343 patients would been suitable PRAMI 196 CVLPRIT; termed ‘observational’ Outcomes determined clinic...

<h3>Introduction</h3> The VISION study demonstrated an association between 30-day mortality after surgery and raised post-operative troponin levels.¹ Subsequently, diagnostic criteria for ‘ischaemic’ MINS were established excluding non-ischaemic aetiology.² We evaluated our initial experiences with monitoring, to look in-depth at patients who suffer events. <h3>Methods</h3> Pre- high-sensitive troponins checked on all elective emergency surgical over 45 years of age...

<h3>Introduction</h3> Despite advances in surgical and anaesthetic techniques, non-cardiac surgery still has a significant mortality. We hypothesised that pre-operative troponin levels might predict post-operative <h3>Methods</h3> Patients undergoing elective urgent/emergency excluding minor procedures were retrospectively assessed for known vascular disease (defined by diagnostic imaging or previous intervention rather than clinical assessment) risk factors including hypertension, treatment...