Lijun Du

ORCID: 0000-0002-4265-944X
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About
Contact & Profiles
Research Areas
  • Ear Surgery and Otitis Media
  • Prenatal Screening and Diagnostics
  • Nasal Surgery and Airway Studies
  • RNA modifications and cancer
  • Chronic Lymphocytic Leukemia Research
  • Immune Cell Function and Interaction
  • Lymphoma Diagnosis and Treatment
  • Microtubule and mitosis dynamics
  • Tracheal and airway disorders
  • Reconstructive Facial Surgery Techniques
  • Ear and Head Tumors
  • Renal and related cancers
  • Genomics and Chromatin Dynamics
  • Ferroptosis and cancer prognosis
  • Genetic Syndromes and Imprinting
  • Circular RNAs in diseases

Southern Medical University
2021-2022

Zhengzhou University
2020

Twelfth Guangzhou City People's Hospital
2020

Shanghai Jiao Tong University
2013

Abstract: Extranodal natural killer (NK)/T-cell lymphoma, nasal type (ENKTL) is a specific subtype of peripheral T cell lymphoma (PTCL) with poor prognosis. To date, there exist no standard therapeutic regimens for relapsed/refractory (R/R) ENKTL. More potent treatment strategies are urgently needed to improve the survival these patients R/R Herein, we present three ENKTL who failed prior therapies (L-asparaginase containing chemotherapy, radiotherapy or biological-cell therapy, etc.)...

10.2147/ott.s262039 article EN OncoTargets and Therapy 2020-07-01

Abstract Background Aneuploidy is the most frequent cause of early-embryo abortion. Any defect in chromosome segregation would fail to satisfy spindle assembly checkpoint (SAC) during mitosis, halting metaphase and causing aneuploidy. The mitotic complex (MCC), comprising MAD1, MAD2, Cdc20, BUBR1 BUB3, plays a vital role SAC activation. Studies have confirmed that overexpression MAD2 can facilitate correct embryo stability. Research also proves miR-125b negatively regulates MAD1 expression...

10.1186/s13039-021-00538-1 article EN cc-by Molecular Cytogenetics 2021-04-26

Objectives: Assess the long‐term outcomes of treating middle ear cholesteatoma with multiple techniques including intact‐canal wall and scute repairing techniques. Methods: One hundred thirteen patients had been treated between 2001 2006. Multiple harvesting bone chips air drill, sculpting autologous grafts, chorda tympani nerve tightening prosthesis, preventing adhesion hyaluronic acid ester membrane, lesion cleaning, reconstruction canal wall, re‐gasification attic and/or mastoid cavity,...

10.1177/0194599814541629a41 article EN Otolaryngology 2014-09-01

Abstract Background: Aneuploid is the most frequent cause of early embryo abortion, and any defect in chromosome segregation would fail to satisfy spindle assembly checkpoint (SAC) during mitosis, which could lead halted metaphase aneuploid occurrence. Mitotic complex(MCC), a complex compound MAD1、MAD2、Cdc20、BUBR1 BUB3, plays an important role SAC activation. Studies have confirmed that overexpression MAD2 BUBR1 can facilitate correct stability. Research identifications also proved miR-125b...

10.21203/rs.3.rs-75451/v1 preprint EN cc-by Research Square (Research Square) 2020-09-17
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