A5100603406- Caching and Content Delivery
- Dermatologic Treatments and Research
- Web Data Mining and Analysis
- Autophagy in Disease and Therapy
- Signaling Pathways in Disease
- Higher Education and Teaching Methods
- Biochemical and Structural Characterization
- Technology and Security Systems
- Advanced Computational Techniques and Applications
- Immune Response and Inflammation
- Cloud Computing and Resource Management
- Data Mining Algorithms and Applications
- Wound Healing and Treatments
- Acupuncture Treatment Research Studies
- Peer-to-Peer Network Technologies
- Data Management and Algorithms
- Inflammatory Bowel Disease
- Alzheimer's disease research and treatments
- Algorithms and Data Compression
- Power Systems and Technologies
- Peptidase Inhibition and Analysis
- Antibiotic Use and Resistance
- RNA Research and Splicing
- Advanced Text Analysis Techniques
- Laser Applications in Dentistry and Medicine
State Key Laboratory of Food Science and Technology
2024
Nanchang University
2024
Tobacco Research Institute
2023-2024
Anhui University of Traditional Chinese Medicine
2024
Hexi University
2011-2023
China Pharmaceutical University
2021-2022
Xiangya Hospital Central South University
2022
Central South University
2022
Peking University
2009-2022
Southern Medical University
2022
the Xiangya Hospital circuit training (X-CircuiT), was developed to reverse pre-frailty in Chinese older adults and determine potential mechanisms through which is reversed.this randomised controlled trial performed at Hospital, Changsha, China from September 2020 May 2021. Forty-eight pre-frail were enrolled. Participants randomly assigned (1:1) X-CircuiT (46 min/session, three supervised sessions/week for 3 months a community health centre) or control (1-time advice on physical activity...
Abstract It is widely accepted that lysosomes are essential for cell homeostasis, and autophagy plays an important role in tumor development. Here, we found FV-429, a synthetic flavonoid compound, inhibited flux, promoted autophagosomes accumulation, lysosomal degradation T-cell malignancies. These effects were likely to be achieved by dysregulation. The destructive of FV-429 on resulted blockage lysosome-associated membrane fusion, permeabilization (LMP), cathepsin-mediated...
Data surveillance and policy interventions can optimize antibiotic use, but few studies have focused on the changes in use after a strict stewardship was implemented China 2012.Based Center for Antibacterial Surveillance, data were collected from general hospitals two provinces of China. Using indicators (e.g. percentage proportion costs) recommended by WHO, this study aimed to identify trends patterns systemic (Anatomical Therapeutic Chemical code J01) 2012-16 explore inappropriate use.This...
Background: Host defense peptides (HDPs) have emerged as a novel therapeutic paradigm for wound management; however, their clinical applications remain challenge owing to poor pharmacological properties and lack of suitable pharmaceutical formulations. Nanodefensin (ND), nanoengineered human α-defensin 5 (HD5), has shown improved relative the parent compound. In this study, we engineered nanodefensin-encased hydrogel (NDEFgel), investigated effects NDEFgel on healing, elucidated underlying...
Background Changes in intestinal flora and barrier patients with preclinical diagnosed rheumatoid arthritis (RA) suggest that play an important role the induction persistence of RA. Huangqin Qingre Chubi Capsule (HQC) is a clinically effective herbal formula for treatment RA, but its therapeutic mechanism has not been fully clarified. Materials methods In this study, real-time qPCR (RT-qPCR), 16SrRNA sequencing, Western blot (WB), immunofluorescence other were used to investigate whether HQC...
After implementing the 2011 national antimicrobial stewardship campaign, few studies focused on evaluating its effect in China's primary care facilities.We randomly selected 11 community health centers Shenzhen, China, and collected all outpatient prescriptions of these from 2010 to 2015. To evaluate impact local interventions antibiotic prescribing, we used a segmented regression model interrupted time series analyze 7 outcomes (ie, percentage with antibiotics, percentages broad-spectrum...
Big data makes cloud computing more and popular in various fields. Video resources are very useful important to education, security monitoring, so on. However, issues of their huge volumes, complex types, inefficient processing performance, weak security, long times for loading pose challenges video resource management. The Hadoop Distributed File System (HDFS) is an open-source framework, which can provide cloud-based platforms presents opportunity solving these problems. This paper...
As the infrastructure of cloud computing, virtualization security problem has become more severe since requirement different virtual machines (VMs) may conflict with others in could computing platform. Based on mandatory access control mechanism, a new mulitlevel model V-MLR is proposed, which not only provided secure communication mechanism for machine monitor (VMM) and VMs, but also updated borrowed information VMM synchronously when it was changed VMs. Case study application Xen showed...
In client-side segmented cache based P2P VOD system, statically cached video files in peers' disks can efficiently improve data acquisition rate. However, since disk space a single peer is very limited, it becomes key problem to design reasonable strategies for replacing those segments. We start at studying the three system models, and analyze necessity of utilizing storage mechanism, then focus on discussing comparing five segment replacement client side: FIFO, LRU, LRF, EDF, LSSF. These...
Abstract BACKGROUND The fruit body of medicinal fungus, Sanghuang ( Inonotus baumii ), is a source diverse metabolites with health‐promoting efficacy through varying mechanisms. low efficiency production and failure to discover valuable have severely limited more extensive applications. RESULTS A novel compound was discovered identified as (6,6′‐bis(( E )‐3,4‐dihydroxystyryl)‐4,4′‐dihydroxy‐2 H ,2′ ‐[3,3′‐bipyran]‐2,2′‐dione (named Phelligridin LA, PLA). exhibited antioxidant activity...