A5062293987- Data-Driven Disease Surveillance
- COVID-19 epidemiological studies
- Influenza Virus Research Studies
- COVID-19 Digital Contact Tracing
- Viral Infections and Outbreaks Research
- Antibiotic Use and Resistance
- Climate Change and Health Impacts
- Travel-related health issues
- Urinary Tract Infections Management
- SARS-CoV-2 and COVID-19 Research
- Biomedical Text Mining and Ontologies
- Bacillus and Francisella bacterial research
- COVID-19 Clinical Research Studies
- Antibiotic Resistance in Bacteria
- COVID-19 and Mental Health
- Global Public Health Policies and Epidemiology
- Bacterial Identification and Susceptibility Testing
- Poxvirus research and outbreaks
- Text and Document Classification Technologies
- Public Health Policies and Education
- Syphilis Diagnosis and Treatment
- Asthma and respiratory diseases
- COVID-19 Pandemic Impacts
- Disaster Response and Management
- Viral gastroenteritis research and epidemiology
UK Health Security Agency
2021-2025
Public Health England
2013-2022
King's College London
2022
Government of the United Kingdom
2021
National Institute for Health Research
2017-2019
Philips (United Kingdom)
2016
Health Protection Agency
2013
Public Health Agency
2011
Environment Agency
2008
Between 7 and 25 May, 86 monkeypox cases were confirmed in the United Kingdom (UK). Only one case is known to have travelled a virus (MPXV) endemic country. Seventy-nine with information male 66 reported being gay, bisexual, or other men who sex men. This first sustained MPXV transmission UK, human-to-human through close contacts, including sexual networks. Improving ascertainment onward-transmission preventive measures are ongoing.
After community transmission of monkeypox virus was identified in Europe, interviews 45 case-patients from England indicated international sexual networks gay and bisexual men since April 2022. Interventions targeting sex-on-premises venues, geospatial dating applications, health services are likely to be critical for outbreak control.
SUMMARY Since April 2015, whole genome sequencing (WGS) has been the routine test for Salmonella identification, surveillance and outbreak investigation at national reference laboratory in England Wales. In May an of Enteritidis cases was detected using WGS data investigated. UK were interviewed to obtain a food history links between suppliers mapped produce chain network chicken eggs. The association phylogeny explored comparison approach. Food environmental samples taken from premises...
BackgroundHouseholds appear to be the highest risk setting for COVID-19 transmission. Large household transmission studies in early stages of pandemic Asia reported secondary attack rates ranging from 5 30%.AimWe aimed investigate dynamics and community settings UK.MethodsA prospective case-ascertained study design based on World Health Organization FFX protocol was undertaken UK following detection first case late January 2020. Household contacts cases were followed using enhanced...
The COVID-19 pandemic is exerting major pressures on society, health and social care services science. Understanding the progression current impact of fundamental to planning, management mitigation future population. Surveillance core function any public system, a multi-component surveillance system for essential understand burden across different strata Many countries bodies utilise 'syndromic surveillance' (using real-time, often non-specific symptom/preliminary diagnosis information...
Abstract Background Households appear to be the highest risk setting for transmission of COVID-19. Large household studies were reported in early stages pandemic Asia with secondary attack rates ranging from 5–30% but few large scale have been conducted outside Asia. Methods A prospective case ascertained study design based on World Health Organization FFX protocol was undertaken UK following detection first late January 2020. Household contacts cases followed using enhanced surveillance...
In the summer of 2009, an outbreak verocytotoxigenic Escherichia coli O157 (VTEC O157) was identified in visitors to a large petting farm South East England. The peak attack rate 6/1000 visitors, and highest those aged <2 years (16/1000). We conducted case-control study with associated microbiological investigations, on human, animal environmental samples. 93 cases; 65 primary, 13 secondary 15 asymptomatic. Cases were more likely have visited specific barn, stayed for prolonged periods be...
Abstract Objectives To retrospectively analyse routine susceptibility testing data to describe antimicrobial non-susceptibility trends in isolates of Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa from urine samples a population 5.6 million people over 4 year period. Methods De-duplicated laboratory submitted the AmSurv surveillance system West Midlands region England results submissions Antimicrobial Resistance Healthcare Associated Infections Reference Unit were...
We investigate the use of Twitter data to deliver signals for syndromic surveillance in order assess its ability augment existing efforts and give a better understanding symptomatic people who do not seek healthcare advice directly. focus on specific syndrome-asthma/difficulty breathing. outline collection using streaming API as well analysis pre-processing collected data. Even with keyword-based collection, many tweets are be relevant because they represent chatter, or talk awareness...
<sec> <title>BACKGROUND</title> Syndromic surveillance now forms an integral part of the for a wide range hazards in many countries. Establishing syndromic systems can be difficult due to different sources data which used, cost pressures, importance security and technologies. </sec> <title>OBJECTIVE</title> We describe major points development UK Health Security Agency (UKHSA) English real-time service over its first two decades (1998 2018) key wider themes we believe are important ensuring...
Objectives: Following detection of the first virologically-confirmed cases COVID-19 in Great Britain, an enhanced surveillance study was initiated by Public Health England to describe clinical presentation, course disease and identify risk factors for infection few hundred cases. Methods: Information collected on according First Few X WHO protocol. Case-control analyses sensitivity, specificity predictive value symptoms were conducted. Point prevalences underlying health conditions among UK...
When an outbreak of a novel pathogen occurs, some the most pressing questions from public-health point view relate to its transmissibility, and probabilities different clinical outcomes following infection, allow informed response. Estimates these quantities are often based on household data due high potential for transmission in this setting, but typically rich spectrum individual-level (from uninfected serious illness) simplified binary (infected or not). We address added benefit retaining...
In Taiwan, around 1,500 cases of dengue fever are reported annually and incidence has been increasing over time. A national web-based Notifiable Diseases Surveillance System (NDSS) in operation since 1997 to monitor trends support case outbreak management. We present the findings an evaluation NDSS ascertain extent which surveillance objectives being achieved.We extracted data on all laboratory-confirmed during 1 January 2010 31 December 2012 assess describe key system attributes based...
Syndromic surveillance aims to provide early warning and real time estimates of the extent incidents; reassurance about lack impact mass gatherings. We describe a novel public health risk assessment process ensure those leading response 2012 Olympic Games were alerted unusual activity that was potential importance, not inundated with multiple statistical 'alarms'. Statistical alarms assessed identify which needed result in 'alerts' as reliably possible. There no previously developed method...
To describe the clinical presentation, course of disease and health-care seeking behaviour first few hundred cases coronavirus 2019 (COVID-19) in United Kingdom Great Britain Northern Ireland.
Introduction In preparation for the London 2012 Olympic Games, existing syndromic surveillance systems operating in England were expanded to include daily general practitioner (GP) out-of-hours (OOH) contacts and emergency department (ED) attendances at sentinel sites (the GP OOH ED systems: GPOOHS EDSSS). Hypothesis/Problem The further development of time Games provided a unique opportunity investigate impact large mass-gathering event on public health services as monitored near real-time...
Abstract Background It is not yet fully understood to what extent in-flight transmission contributed the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This study aimed determine occurrence and SARS-CoV-2 assess factors associated with risk inform future control strategies. Methods Retrospective cohort using data obtained from contact tracing international flights arriving in England between 02/08/2021–15/10/2021. Transmission was estimated by calculating secondary...
There is a marked variation in both antibiotic prescribing practice and urine sampling rates for diagnostic microbiology across general practices England. To help understand factors driving this variation, we undertook survey 2012/13 to determine protocols formularies used by practitioners (GPs) managing urinary tract infections (UTIs) the West Midlands region of Cross-sectional all eligible England undertaken November 2012. GPs were invited complete an online questionnaire gather...