- COVID-19 epidemiological studies
- COVID-19 and Mental Health
- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Viral gastroenteritis research and epidemiology
- Health disparities and outcomes
- SARS-CoV-2 and COVID-19 Research
- Parvovirus B19 Infection Studies
- Virus-based gene therapy research
- Viral Infections and Outbreaks Research
- COVID-19 Impact on Reproduction
- Data-Driven Disease Surveillance
- Respiratory viral infections research
- Chronic Disease Management Strategies
- Primary Care and Health Outcomes
- Influenza Virus Research Studies
- SARS-CoV-2 detection and testing
- Long-Term Effects of COVID-19
- Climate Change and Health Impacts
- Hepatitis C virus research
- Global Public Health Policies and Epidemiology
- COVID-19 and healthcare impacts
- HIV, Drug Use, Sexual Risk
- Food Security and Health in Diverse Populations
- Clinical Nutrition and Gastroenterology
UK Health Security Agency
2022-2024
Public Health England
2020-2022
London School of Hygiene & Tropical Medicine
2022
Government of the United Kingdom
2020
BackgroundHouseholds appear to be the highest risk setting for COVID-19 transmission. Large household transmission studies in early stages of pandemic Asia reported secondary attack rates ranging from 5 30%.AimWe aimed investigate dynamics and community settings UK.MethodsA prospective case-ascertained study design based on World Health Organization FFX protocol was undertaken UK following detection first case late January 2020. Household contacts cases were followed using enhanced...
England has experienced one of the highest excess in all-cause mortality Europe during current COVID-19 pandemic. As emerged, rapidly increased, starting March 2020. The observed pandemic was higher than excesses noted past 5 years. It concerned all regions and age groups, except 0–14 year olds, but more pronounced London region those aged ≥ 85
Abstract Background Households appear to be the highest risk setting for transmission of COVID-19. Large household studies were reported in early stages pandemic Asia with secondary attack rates ranging from 5–30% but few large scale have been conducted outside Asia. Methods A prospective case ascertained study design based on World Health Organization FFX protocol was undertaken UK following detection first late January 2020. Household contacts cases followed using enhanced surveillance...
An increase in acute severe hepatitis of unknown aetiology previously healthy children the UK March, 2022, triggered global case-finding. We aimed to describe epidemiological investigations cases and their possible causes.We actively surveilled unexplained paediatric (transaminase >500 international units per litre) younger than 16 years presenting since Jan 1, through notifications from paediatricians, microbiologists, liver units; we collected demographic, clinical, exposure information....
Objectives: Following detection of the first virologically-confirmed cases COVID-19 in Great Britain, an enhanced surveillance study was initiated by Public Health England to describe clinical presentation, course disease and identify risk factors for infection few hundred cases. Methods: Information collected on according First Few X WHO protocol. Case-control analyses sensitivity, specificity predictive value symptoms were conducted. Point prevalences underlying health conditions among UK...
To describe the clinical presentation, course of disease and health-care seeking behaviour first few hundred cases coronavirus 2019 (COVID-19) in United Kingdom Great Britain Northern Ireland.
Background A multi-tiered surveillance system based on influenza was adopted in the United Kingdom early stages of coronavirus disease (COVID-19) epidemic to monitor different disease. Mandatory social and physical distancing measures (SPDM) were introduced 23 March 2020 attempt limit transmission. Aim To describe impact SPDM COVID-19 activity as detected through systems. Methods Data from national population surveys, web-based indicators, syndromic surveillance, sentinel swabbing,...
In England, the emergence more transmissible SARS-CoV-2 variant Alpha (B.1.1.7) led to a third national lockdown from December 2020, including restricted attendance at schools. Nurseries, however, remained fully open. COVID-19 outbreaks (≥ 2 laboratory-confirmed cases within 14 days) in nurseries were investigated assess risk of infection and cumulative incidence staff children over three-month period when community infections rates high was spreading rapidly across England.This...
Background: The reopening of schools during the COVID-19 pandemic has raised concern for safety staff and students, their families wider community. We monitored SARS-CoV-2 infection rates in school-aged children compared them with adult before after reopened England. Methods: Public Health England receives daily electronic reports all tests nationally. by school year from July to November 2020 were analysed, including effect a week-long half-term break October national month-long lockdown...
Background: Mandatory social and physical distancing measures (SPDM) were introduced in the UK on 23rd March 2020. A multi-tiered surveillance system based influenza surveillance, was adopted from early stages of COVID-19 Epidemic to monitor different disease. We describe how impact SPDM detected through each these systems may be applied detect increases activity as are eased.Methods: Data national population surveys, web-based indicators, syndromic sentinel swabbing, respiratory outbreaks,...
Abstract Background In England, the emergence more transmissible SARS-CoV-2 variant Alpha (B.1.1.7) led to a third national lockdown from December 2020, including restricted attendance at schools. Nurseries, however, remained fully open. COVID-19 outbreaks (≥ 2 laboratory-confirmed cases within 14 days) in nurseries and assess risk of infection incidence rates staff children over three-month period when community infections were high was spreading rapidly across England. Methods This...