A5091133955- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Animal Disease Management and Epidemiology
- Virology and Viral Diseases
- Pneumonia and Respiratory Infections
- Kawasaki Disease and Coronary Complications
- COVID-19 and healthcare impacts
- Mechanical Circulatory Support Devices
- School Health and Nursing Education
- Bacterial Infections and Vaccines
- Liver Disease Diagnosis and Treatment
- Cancer-related cognitive impairment studies
- Vector-Borne Animal Diseases
- Palliative Care and End-of-Life Issues
- HIV, Drug Use, Sexual Risk
- Long-Term Effects of COVID-19
- Animal Behavior and Welfare Studies
- Cardiac Structural Anomalies and Repair
- Hepatitis Viruses Studies and Epidemiology
UK Health Security Agency
2022
Public Health England
2013-2021
Trinity College Dublin
2019
Centre for Immunity, Infection and Evolution
2013
University of Edinburgh
2013
Imperial College London
2013
Università Cattolica del Sacro Cuore
1979
Paediatric Multisystem Inflammatory Syndrome temporally associated with SARS-CoV-2 (PIMS-TS), first identified in April 2020, shares features of both Kawasaki disease (KD) and toxic shock syndrome (TSS). The surveillance describes the epidemiology clinical characteristics PIMS-TS United Kingdom Ireland. Public Health England initiated prospective national through British Surveillance Unit. Paediatricians were contacted monthly to report PIMS-TS, KD TSS cases electronically complete a...
The full reopening of schools in September 2020 was associated with an increase COVID-19 cases and outbreaks educational settings across England.Primary secondary reporting outbreak (≥2 laboratory-confirmed within 14 days) to Public Health England (PHE) between 31 August 18 October were contacted November complete online questionnaire.There 969 school reported PHE, comprising 2% (n = 450) primary 10% 519) England. Of the 369 geographically-representative contacted, 179 completed...
Abstract Background Most individuals with COVID-19 will recover without sequelae, but some develop long- term multi-system impairments. The definition, duration, prevalence and symptoms associated long COVID, however, have not been established. Methods Public Health England (PHE) initiated longitudinal surveillance of clinical non-clinical healthcare workers for monthly blood sampling SARS-CoV-2 antibodies in March 2020. Eight months after enrolment, participants completed an online...
Older children have higher SARS-CoV-2 infection rates than younger children. We investigated infection, seroprevalence and seroconversion in staff students following the full reopening of all secondary schools England.Public Health England (PHE) invited six regions (East West London, Hertfordshire, Derbyshire, Manchester Birmingham) to participate surveillance during 2020/21 academic year. Participants had nasal swabs for RT-PCR blood samples antibodies at beginning (September 2020) end...
A national seroprevalence study was performed to determine the prevalence of Haemophilus influenzae type b (Hib) antibodies in England and Wales 2009, when Hib disease incidence lowest ever recorded. total 2,693 anonymised residual sera from routine diagnostic testing submitted by participating National Health Service hospital laboratories were tested for anti-polyribosyl-ribitol phosphate (PRP) IgG using a fluorescent bead assay. Median anti-PRP concentrations highest toddlers aged 1–4...
Abstract Background Little is known about the views of adolescents returning to secondary school during current COVID-19 pandemic. Methods In September 2020, UK Health Security Agency (UKHSA), formerly as Public England (PHE),recruited staff and students in schools provide nasal swabs, oral fluid blood samples for SARS-CoV-2 infection antibody testing. Students aged 11–18 years five London completed a short questionnaire their perception pandemic, school, risk themselves others control...
When modelling infectious diseases, accurately capturing the pattern of dissemination through space is key to providing optimal recommendations for control. Mathematical models disease spread in livestock, such as foot-and-mouth (FMD), have done this by incorporating a transmission kernel which describes decay rate with increasing Euclidean distance from an infected premises (IP). However, assumes homogenous landscape, and based on between point locations farms. Indeed, underlying spatial...
Abstract Background Antibody waning after SARS-CoV-2 infection may result in reduction long-term immunity following natural and vaccination, is therefore a major public health issue. We undertook prospective serosurveillance large cohort of healthy adults from the start epidemic England. Methods Clinical non-clinical healthcare workers were recruited across three English regions tested monthly March to November 2020 for spike (S) protein nucleoprotein (N) antibodies using five different...
This study aimed to estimate the prevalence of childhood chronic hepatitis B (CHB) infection diagnosed in England using capture-recapture analysis 2 independent data sources and describe clinical epidemiological characteristics, management, complications outcome children with CHB.Pediatric specialists were contacted report all CHB cases aged <16 years complete a standardized questionnaire. Capture-recapture during 2001-2009 was performed CHB.Capture-recapture estimated 448 (prevalence,...
SUMMARY Despite national guidance recommending testing and vaccination of household contacts hepatitis B-infected pregnant women, provision uptake this is sub-optimal. The aim study was to evaluate the use in-home dried blood spot (DBS) increase women as an alternative approach conventional primary-care follow-up. conducted across two London maternity trusts (North Middlesex Newham). All B surface antigen-positive identified through these were eligible for inclusion. intervention DBS...
Background: Many countries re-opened schools after national lockdown but little is known about the risk of SARS-CoV-2 infection and transmission in educational settings. Public Health England conducted six-month prospective surveillance primary across England. Methods: The COVID-19 Surveillance School KIDs (sKIDs) study included two arms: weekly nasal swabs for ≥4 weeks following partial reopening during summer half-term (June to mid-July 2020) blood sampling with throat at beginning end...
The reopening of schools during the COVID-19 pandemic has raised concerns about widespread infection and transmission SARS-CoV-2 in educational settings. In June 2020, Public Health England (PHE) initiated prospective national surveillance primary across (sKIDs). We used this opportunity to assess feasibility agreeability large-scale testing for infections school among staff, parents students.Staff students 131 were asked complete a questionnaire at recruitment provide weekly nasal swabs...
Background: The full reopening of schools in September 2020 was associated with an increase COVID-19 cases and outbreaks educational settings across England.Methods: Primary secondary reporting outbreak (≥2 laboratory-confirmed within 14 days) to Public Health England (PHE) between 31 August 18 October were contacted complete online questionnaire.Interpretation: There 969 primary (n=450) school (n=519) reported PHE, representing 3% 15% England. Of the 369 contacted, 190...
In England, the emergence more transmissible SARS-CoV-2 variant Alpha (B.1.1.7) led to a third national lockdown from December 2020, including restricted attendance at schools. Nurseries, however, remained fully open. COVID-19 outbreaks (≥ 2 laboratory-confirmed cases within 14 days) in nurseries were investigated assess risk of infection and cumulative incidence staff children over three-month period when community infections rates high was spreading rapidly across England.This...
Background: The full reopening of schools in September 2020 was associated with an increase COVID-19 cases and outbreaks educational settings across England. Methods: Primary secondary reporting outbreak (≥2 laboratory-confirmed within 14 days) to Public Health England (PHE) between 31 August 18 October were contacted complete online questionnaire. Interpretation: There 969 primary (n=450) school (n=519) reported PHE, representing 3% 15% Of the 369 contacted, 190...
Background: The COVID-19 pandemic in the UK began late January 2020 and peaked mid-April before declining. Children typically develop only very mild symptoms it remains unclear what role children play spread of COVID-19. aim this study was to report prevalence SARS-CoV-2 antibodies healthy healthcare workers. Methods: Healthy workers, were recruited London during May 2020. Participants had nose throat swabs tested for infection via RT-qPCR blood serums samples immunoglobulin G (IgG)...
Background: Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), first identified in April 2020, shares features of both Kawasaki disease (KD) and toxic shock (TSS). Methods: Public Health England initiated prospective national surveillance PIMS-TS through the British Surveillance Unit. Paediatricians were contacted monthly to report PIMS-TS, KD TSS cases electronically complete a detailed clinical questionnaire. Cases symptom onset between 01 March...
Background: The reopening of schools during the COVID-19 pandemic has raised concerns about widespread infection and transmission SARS-CoV-2 in educational settings. In June 2020, Public Health England (PHE) initiated prospective national surveillance primary across (sKIDs). We used this opportunity to assess feasibility agreeability large-scale testing for infections school among staff, parents students.Methods: Staff students 131 were asked complete a questionnaire at recruitment provide...
Background: The reopening of schools during the COVID-19 pandemic has raised concerns about widespread infection and transmission SARS-CoV-2 in educational settings. In June 2020, Public Health England (PHE) initiated prospective national surveillance primary across (sKIDs). We used this opportunity to assess feasibility agreeability large-scale testing for infections school among staff, parents students.Methods: Staff students 131 were asked complete a questionnaire at recruitment provide...
A recent London study has shown that the use of home delivered dried blood spot (DBS) testing significantly increases screening household contacts (HHCs) hepatitis B (HBV) infected pregnant women, particularly amongst partners. The also identified an unexpectedly high number chronically contacts. This follow up aims to estimate transmission rates among woman and their HHCs by performing sequence analysis on residual serum samples from case DBS Genotype determination across HBsAg region was...